Volume 6 Issue 3
May  2015
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Li Zhibin, Zhang Geng, Liu Kepu, et al. Clinical diagnosis and treatment of chronic diarrhea after renal transplantation[J]. ORGAN TRANSPLANTATION, 2015, 6(3): 184-189. doi: 10.3969/j.issn.1674-7445.2015.03.011
Citation: Li Zhibin, Zhang Geng, Liu Kepu, et al. Clinical diagnosis and treatment of chronic diarrhea after renal transplantation[J]. ORGAN TRANSPLANTATION, 2015, 6(3): 184-189. doi: 10.3969/j.issn.1674-7445.2015.03.011
shu

Clinical diagnosis and treatment of chronic diarrhea after renal transplantation

doi: 10.3969/j.issn.1674-7445.2015.03.011

  • Department of Urology, Xijing Hospital, the Fourth Military Medical University, Xi'an 710032, China

More Information
  • Corresponding author: Yuan Jianlin, Email: jianliny@fmmu.edu.cn
  • Received Date: 2015-02-10
    Available Online: 2021-01-19
  • Publish Date: 2015-05-15
    Abstract
  •   Objective  To investigate the diagnosis and treatment regimen for patients with chronic diarrhea after renal transplantation.   Methods  The clinical data of 353 patients with chronic diarrhea who underwent renal allograft transplantation at Department of Urology of Xijing Hospital from January 2007 to June 2014 with regular follow-up were analyzed retrospectively. The occurrence of chronic diarrhea after renal transplantation was observed, including incidence, time of occurrence, course of disease and complications. The changes in general conditions and auxiliary examination indexes (body mass index, anemia and other auxiliary examination indexes), treatment and prognosis of the patients with chronic diarrhea were recorded.   Results  Fifteen cases (4.2%)of 353 renal transplant recipients had chronic diarrhea. The time of symptomatic and etiological treatment was (15±7) d. Two patients died during diarrhea (died from gastrointestinal hemorrhage and sudden death caused by severe hypokalemia respectively) and other patients were recovered. Among the 13 patients, 5 cases had good prognosis, 2 cases died(both died from pulmonary infection), 5 cases suffered from renal allograft dysfunction and 1 case suffered from renal allograft insufficiency during the follow-up.   Conclusions  The etiology of chronic diarrhea after renal transplantation is complex and the patients should receive symptomatic and etiological treatment. The patients with chronic diarrhea after renal transplantation combined with severe complications have poor prognosis.

     

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