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常温机械灌注技术在离断肢体保存中的作用研究进展

贾志博, 管延军, 宋翔宇, 等. 常温机械灌注技术在离断肢体保存中的作用研究进展[J]. 器官移植. doi: 10.3969/j.issn.1674-7445.2024062
引用本文: 贾志博, 管延军, 宋翔宇, 等. 常温机械灌注技术在离断肢体保存中的作用研究进展[J]. 器官移植. doi: 10.3969/j.issn.1674-7445.2024062
Jia Zhibo, Guan Yanjun, Song Xiangyu, et al. Research progress on the role of normothermic machine perfusion in the preservation of severed limbs[J]. ORGAN TRANSPLANTATION. doi: 10.3969/j.issn.1674-7445.2024062
Citation: Jia Zhibo, Guan Yanjun, Song Xiangyu, et al. Research progress on the role of normothermic machine perfusion in the preservation of severed limbs[J]. ORGAN TRANSPLANTATION. doi: 10.3969/j.issn.1674-7445.2024062

常温机械灌注技术在离断肢体保存中的作用研究进展

doi: 10.3969/j.issn.1674-7445.2024062
基金项目: 国家重点研发计划(2019YFA0110704);解放军总医院青年自主创新科学基金项目(22QNFC014)
详细信息
    作者简介:
    通讯作者:

    彭江(ORCID 0000 0003 4662 9288),主任医师,教授,博士研究生导师,研究方向为股骨头坏死保髋治疗、关节软骨损伤修复、周围神经损伤修复、离断肢体保存及骨科康复治疗,Email:pengjiang301@126.com

  • 中图分类号: R617, R658

Research progress on the role of normothermic machine perfusion in the preservation of severed limbs

More Information
  • 摘要: 肢体离断伤在临床工作中较为常见,对离断肢体实施安全有效的保护是肢体再植成功的关键。常温机械灌注技术已经在器官移植领域取得很大突破,可长时间维持器官和组织的活性功能,延长其保存时间,在大动物模型以及临床应用中得到了很好的验证。同时这项技术有望为离断肢体的保存和功能恢复提供新的参考。因此,本文就静态冷保存在离断肢体保存中存在的问题、机械灌注的发展历程、离断肢体常温机械灌注的临床应用现状以及有待解决问题进行综述,并展望其发展方向和临床应用前景,以期推动该技术在临床广泛应用。

     

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  • 收稿日期:  2024-04-20
  • 网络出版日期:  2024-07-08

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