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摘要: 互噬作用是指细胞通过直接接触发生的部分细胞膜片段或细胞浆内容交换的过程,是存在于细胞间的一种相互作用机制。免疫细胞可通过互噬作用获得对方细胞的部分特性,通过互噬作用产生的新细胞在移植免疫耐受的诱导中可能起到重要作用。本文就细胞互噬作用研究的起源和发展、细胞互噬作用的机制及免疫细胞互噬作用的生物学意义进行综述。Abstract: Trogocytosis is a process of exchanging part of the membrane fragment or cytoplasmic content of cells through direct contact, and it's an interaction mechanism that exists between cells. Immune cell can obtain some characteristics of other cells through trogocytosis, and the new cells generated through trogocytosis may play an important role in the induction of graft immune tolerance. In this article, the origin and development of research on cell trogocytosis, mechanism of cell trogocytosis and biological significance of trogocytosis of immune cell were reviewed.
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Key words:
- Trogocytosis /
- Immune cell /
- Immune regulation /
- Phagocytosis /
- Antigen presentation /
- Transplantation immunity /
- Tumor immunity /
- Cell killer
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