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肺移植治疗囊性纤维化1例并文献复习

陈奥 练巧燕 徐鑫 韦兵 刘梦杨 彭桂林 张建恒 何建行 巨春蓉

陈奥, 练巧燕, 徐鑫, 等. 肺移植治疗囊性纤维化1例并文献复习[J]. 器官移植, 2020, 11(3): 391-394,423. doi: 10.3969/j.issn.1674-7445.2020.03.012
引用本文: 陈奥, 练巧燕, 徐鑫, 等. 肺移植治疗囊性纤维化1例并文献复习[J]. 器官移植, 2020, 11(3): 391-394,423. doi: 10.3969/j.issn.1674-7445.2020.03.012
Chen Ao, Lian Qiaoyan, Xu Xin, et al. Lung transplantation for cystic fibrosis: a case report and literature review[J]. ORGAN TRANSPLANTATION, 2020, 11(3): 391-394,423. doi: 10.3969/j.issn.1674-7445.2020.03.012
Citation: Chen Ao, Lian Qiaoyan, Xu Xin, et al. Lung transplantation for cystic fibrosis: a case report and literature review[J]. ORGAN TRANSPLANTATION, 2020, 11(3): 391-394,423. doi: 10.3969/j.issn.1674-7445.2020.03.012

肺移植治疗囊性纤维化1例并文献复习

doi: 10.3969/j.issn.1674-7445.2020.03.012
基金项目: 

广东省自然科学基金 2018A030313107

详细信息
    作者简介:

    陈奥,女,硕士研究生,研究方向为肺移植术后并发症,Email:1131343416@qq.com

    通讯作者:

    巨春蓉,女,主任医师,教授,硕士研究生导师,研究方向为终末期肺疾病肺移植术前评估与术后并发症诊治,E-mail:juchunrong@126.com

  • 中图分类号: R617, R563

Lung transplantation for cystic fibrosis: a case report and literature review

More Information
  • 摘要:   目的   探讨肺移植治疗囊性纤维化(CF)的疗效和预后。   方法   回顾性分析行同种异体双肺移植术治疗1例终末期CF受者的临床资料,对CF受者的临床特点、诊断方法及治疗策略进行总结。   结果   本例受者幼年发病,反复咳嗽、咳浓痰30年,肺部反复感染合并急性加重、慢性鼻窦炎及极重度营养不良,肺移植术前因呼吸肌无力难以脱离有创呼吸机,长期入住重症监护室(ICU)。影像学检查提示双肺多发囊柱状支气管扩张伴感染,经汗液测试和基因检测进一步确诊为CF。该受者2017年8月17日接受双肺移植术后经过康复治疗,肺功能逐渐恢复正常,康复后至投稿日已2年余,享有与同龄健康人同等的生活质量。   结论   肺移植术作为终末期CF的有效治疗手段,不仅能挽救患者生命,而且还能显著提高患者的生活质量。

     

  • 图  1  肺移植受者手术前后的胸部CT表现

    注:A、C图示术前肺窗;B、D图示术后2年肺窗。

    Figure  1.  Chest CT manifestations of the lung transplant recipient before and after surgery

    图  2  CF的诊断流程图

    (资料来源:参考文献 [7])

    Figure  2.  Diagnostic flow chart of CF

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出版历程
  • 网络出版日期:  2021-01-19
  • 刊出日期:  2020-05-15

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