谈宜斌, 金学兰, 李源, 等. 肾移植受者术后医院感染流行病学单中心分析[J]. 器官移植, 2019, 10(4): 429-433. DOI: 10.3969/j.issn.1674-7445.2019.04.013
引用本文: 谈宜斌, 金学兰, 李源, 等. 肾移植受者术后医院感染流行病学单中心分析[J]. 器官移植, 2019, 10(4): 429-433. DOI: 10.3969/j.issn.1674-7445.2019.04.013
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Tan Yibin, Jin Xuelan, Li Yuan, et al. Epidemiology of nosocomial infection in recipients after renal transplantation: a single-center analysis[J]. ORGAN TRANSPLANTATION, 2019, 10(4): 429-433. DOI: 10.3969/j.issn.1674-7445.2019.04.013
Citation: Tan Yibin, Jin Xuelan, Li Yuan, et al. Epidemiology of nosocomial infection in recipients after renal transplantation: a single-center analysis[J]. ORGAN TRANSPLANTATION, 2019, 10(4): 429-433. DOI: 10.3969/j.issn.1674-7445.2019.04.013
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肾移植受者术后医院感染流行病学单中心分析

Epidemiology of nosocomial infection in recipients after renal transplantation: a single-center analysis

    摘要
  • 摘要:
      目的  探讨肾移植受者术后医院感染流行病学特点及其防控措施。
      方法  2014年1月至2017年12月对456例肾移植受者进行监测，分析肾移植术后医院感染情况，包括基本情况、感染部位、感染病原体类型。
      结果  456例肾移植受者中，发生医院感染78例（17.1%），术后感染时间为9（3~21）d。感染部位主要为下呼吸道、泌尿系统和血流感染。感染病原体类型包括葡萄球菌13株、屎肠球菌6株、真菌6株、嗜麦芽窄食单胞菌4株、鲍曼不动杆菌4株、铜绿假单胞菌4株、表皮葡萄球菌4株、肺炎克雷伯菌1株、大肠埃希菌1株、其他阴性菌9株。其中多重耐药菌感染11例（14%），死亡4例。
      结论  肾移植受者术后医院感染发生率较高、术后发病早、多重耐药菌感染常见且病死率高，应充分做好术前准备、积极预防术后下呼吸道感染、规范实施多重耐药菌防治措施。

     

    Abstract:
      Objective  To investigate the epidemiological characteristics of renal transplantation recipients, effective prevention and control measures.
      Methods  A total of 456 renal transplant recipients were monitored from January 2014 to December 2017. Postoperative infection including baseline data, infection site and infectious pathogen type was analyzed.
      Results  Among 456 renal transplant recipients, 78 cases (17.1%) developed nosocomial infection. Postoperative infection time was 9(3-21) d. Infection sites mainly included the lower respiratory tract, urinary system and blood infection. Infection pathogens consisted of Staphylococci (n=13), Enterococcus faecium (n=6), fungi (n=6), Stenotrophomonas maltophilia (n=4), Acinetobacter baumannii (n=4), Pseudomonas aeruginosa (n=4), Staphylococcus epidermidis (n=4), Klebsiella pneumoniae (n=1), Escherichia coli (n=1) and other negative bacteria (n=9). Among them, 11 cases (14%) were infected with multi-drug resistant bacteria, and 4 cases died.
      Conclusions  In renal transplant recipients, the incidence of nosocomial infection is relatively high, with early postoperative onset, common multiple drug-resistant bacterial infection and high mortality. Preoperative preparations should be fully implemented, postoperative lower respiratory tract infection should be actively prevented and prevention and treatment measures for multidrug-resistant bacteria should be standardized.

     

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