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摘要: 长链非编码核糖核酸(lncRNA)是长度大于200个核苷酸的非编码RNA,它具有广泛的组织表达谱。研究发现,lncRNA在许多生物学活动中都发挥重要作用,它的异常表达与个体发育和疾病之间存在联系。移植后免疫排斥反应是目前移植工作中最困扰研究者的问题之一,近些年来lncRNA与免疫系统各组成部分之间的相关性逐渐有文献报道,但目前对移植免疫与lncRNA之间的关系研究甚少。本文就近年来lncRNA在免疫系统,特别是移植免疫中的研究进展作一简述,为移植免疫相关研究提供参考。
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关键词:
- 长链非编码核糖核酸(lncRNA) /
- 微小核糖核酸(miRNA) /
- 信使核糖核酸(mRNA) /
- 器官移植 /
- 移植免疫 /
- 固有免疫 /
- 适应性免疫 /
- 自身免疫性疾病
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