Abstract: Organ donation and transplantation in China have developed rapidly, ranking second in the world in terms of both donation and transplantation volume. However, both the quantity and quality of organ transplants remain to be further improved to satisfy the demands of the vast number of recipients awaiting transplantation. Artificial intelligence (AI) facilitates the integration, analysis, and application of multi-source clinical big data. It is capable of assisting in expanding the pool of available donor organs and enhancing graft quality, thereby providing a novel technological foundation for alleviating the imbalance between the supply and demand of transplant organs. To standardize the auxiliary application of AI throughout the entire process of organ donation and transplantation in China, a team of multidisciplinary experts were convened to formulate the Chinese Expert Consensus on AI-Assisted Clinical Decision-Making in Organ Transplantation. By establishing unified requirements for data and models, this consensus forms a technical framework covering clinical scenarios across the entire workflow of organ donation and transplantation, including donor assessment and maintenance, organ matching, organ preservation and transport, transplant surgery, and post-transplant recipient management. Furthermore, it clarifies ethical and regulatory constraints as well as the boundaries of responsibility subjects. The aim is to further enhance the standardization and safety of AI-assisted organ donation and transplantation, ultimately promoting the high-quality development of this field in China.