Research progress on anatomic vascular reconstruction in rat models of orthotopic liver transplantation

Wu Weikang; Li Xiao; Wang Xudan; Ding Rui; Tao Kaishan

doi:10.3969/j.issn.1674-7445.2024037

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Wu Weikang, Li Xiao, Wang Xudan, et al. Research progress on anatomic vascular reconstruction in rat models of orthotopic liver transplantation[J]. ORGAN TRANSPLANTATION. doi: 10.3969/j.issn.1674-7445.2024037

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Research progress on anatomic vascular reconstruction in rat models of orthotopic liver transplantation

doi: 10.3969/j.issn.1674-7445.2024037

Department of Hepatobiliary-pancreatic-splenic Surgery, Xijing Hospital of Air Force Medical University, Xi’an 710032, China

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Corresponding author: Tao Kaishan, Email: taokaishan0686@163.com
Received Date: 2024-02-01
Available Online: 2024-03-07

Abstract

Abstract

Establishment of rat models of liver transplantation provides an ideal animal model for resolving the problems of postoperative complications and perioperative treatment of liver transplantation. With in-depth study of the establishment of rat models of liver transplantation, classic "two-cuff" technique has been gradually employed. However, poor surgical field, vascular torsion, biliary tract injury and long anhepatic phase remain unresolved in the process of liver transplantation using traditional techniques. At present, the rat models of liver transplantation at home and abroad are modified mainly from the reconstruction of four vital anatomic structures including the suprahepatic inferior vena cava, portal vein, infrahepatic inferior vena cava and bile duct. Therefore, the latest progress in the reconstruction of the suprahepatic inferior vena cava, portal vein, infrahepatic inferior vena cava and bile duct was reviewed, aiming to provide reference for the establishment of rat models of liver transplantation and promote further development of liver transplantation techniques.
- Orthotopic liver transplantation,
- Rat,
- Vascular anastomosis,
- Magnetic ring anastomosis,
- Suprahepatic inferior vena cava,
- Portal vein,
- Infrahepatic inferior vena cava,
- Bile duct

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References(40)

References

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Research progress on anatomic vascular reconstruction in rat models of orthotopic liver transplantation

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Research progress on anatomic vascular reconstruction in rat models of orthotopic liver transplantation

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