Citation: | Sun Shengkun, Yang Shujun, Wei Hao, et al. Application of xenotransplantation in clinical practice[J]. ORGAN TRANSPLANTATION, 2024, 15(2): 200-206. doi: 10.3969/j.issn.1674-7445.2023234 |
[1] |
许艺红, 肖义军. 猪作为人类器官移植供体的研究进展[J]. 生物学通报, 2022, 57(11): 1-4. DOI: 10.3969/j.issn.0006-3193.2022.11.001.
XU YH, XIAO YJ. Research progress on pigs as human organ transplant donors[J]. Bull Biol, 2022, 57(11): 1-4. DOI: 10.3969/j.issn.0006-3193.2022.11.001.
|
[2] |
窦科峰, 张玄. 临床异种器官移植十大问题的思考[J]. 器官移植, 2022, 13(4): 411-416. DOI: 10.3969/j.issn.1674-7445.2022.04.001.
DOU KF, ZHANG X. Reflection on 10 problems of clinical xenotransplantation[J]. Organ Transplant, 2022, 13(4): 411-416. DOI: 10.3969/j.issn.1674-7445.2022.04.001.
|
[3] |
Um medicine faculty-scientists and clinicians perform second historic transplant of pig heart into patient with end-stage cardiovascular disease[EB/OL]. [2023-11-01].https://www.umms.org/ummc/news/2023/um-medicine-clinicians-perform-second-historic-transplant-of-pig-heart-into-patient.
|
[4] |
In memoriam: xenotransplant patient lawrence faucette[EB/OL]. [2023-11-01]. https://www.umms.org/ummc/news/2023/announcing-the-passing-of-lawrence-faucette.
|
[5] |
Two-month study of pig kidney xenotransplantation gives new hope to the future of the organ supply[EB/OL]. [2023-11-01]. https://nyulangone.org/news/two-month-study-pig-kidney-xenotransplantation-gives-new-hope-future-organ-supply.
|
[6] |
MOAZAMI N, STERN JM, KHALIL K, et al. Pig-to-human heart xenotransplantation in two recently deceased human recipients[J]. Nat Med, 2023, 29(8): 1989-1997. DOI: 10.1038/s41591-023-02471-9.
|
[7] |
Porcine kidney xenotransplantation in patients with end-stage kidney disease[EB/OL]. [2023-11-01]. https://clinicaltrials.gov/study/NCT05340426?term=Porcine%20Kidney%20Xenotransplantation%20in%20Patients%20With%20End-Stage%20Kidney%20Disease&rank=1.
|
[8] |
HAWTHORNE WJ. World first pig-to-human cardiac xenotransplantation[J]. Xenotransplantation, 2022, 29(1): e12733. DOI: 10.1111/xen.12733.
|
[9] |
MOHIUDDIN MM, SINGH AK, SCOBIE L, et al. Graft dysfunction in compassionate use of genetically engineered pig-to-human cardiac xenotransplantation: a case report[J]. Lancet, 2023, 402(10399): 397-410. DOI: 10.1016/S0140-6736(23)00775-4.
|
[10] |
GRIFFITH BP, GOERLICH CE, SINGH AK, et al. Genetically modified porcine-to-human cardiac xenotransplantation[J]. N Engl J Med, 2022, 387(1): 35-44. DOI: 10.1056/NEJMoa2201422.
|
[11] |
PORRETT PM, ORANDI BJ, KUMAR V, et al. First clinical-grade porcine kidney xenotransplant using a human decedent model[J]. Am J Transplant, 2022, 22(4): 1037-1053. DOI: 10.1111/ajt.16930.
|
[12] |
MONTGOMERY RA, STERN JM, LONZE BE, et al. Results of two cases of pig-to-human kidney xenotransplantation[J]. N Engl J Med, 2022, 386(20): 1889-1898. DOI: 10.1056/NEJMoa2120238.
|
[13] |
LOUPY A, GOUTAUDIER V, GIARRAPUTO A, et al. Immune response after pig-to-human kidney xenotransplantation: a multimodal phenotyping study[J]. Lancet, 2023, 402(10408): 1158-1169. DOI: 10.1016/S0140-6736(23)01349-1.
|
[14] |
GAO M, ZHANG J, WANG R, et al. Pig-to-human xenotransplantation: moving toward organ customization[J]. Precis Clin Med, 2023, 6(2): pbad013. DOI: 10.1093/pcmedi/pbad013.
|
[15] |
SINGH AK, CHAN JL, SEAVEY CN, et al. CD4+CD25HiFoxP3+ regulatory T cells in long-term cardiac xenotransplantation[J]. Xenotransplantation, 2018, 25(2): e12379. DOI: 10.1111/xen.12379.
|
[16] |
ANAND RP, LAYER JV, HEJA D, et al. Design and testing of a humanized porcine donor for xenotransplantation[J]. Nature, 2023, 622(7982): 393-401. DOI: 10.1038/s41586-023-06594-4.
|
[17] |
DENNER J, LÄNGIN M, REICHART B, et al. Impact of porcine cytomegalovirus on long-term orthotopic cardiac xenotransplant survival[J]. Sci Rep, 2020, 10(1): 17531. DOI: 10.1038/s41598-020-73150-9.
|
[18] |
NIU D, WEI HJ, LIN L, et al. Inactivation of porcine endogenous retrovirus in pigs using CRISPR-Cas9[J]. Science, 2017, 357(6357): 1303-1307. DOI: 10.1126/science.aan4187.
|
[19] |
LÄNGIN M, MAYR T, REICHART B, et al. Consistent success in life-supporting porcine cardiac xenotransplantation[J]. Nature, 2018, 564(7736): 430-433. DOI: 10.1038/s41586-018-0765-z.
|
[20] |
BIKHET M, IWASE H, YAMAMOTO T, et al. What therapeutic regimen will be optimal for initial clinical trials of pig organ transplantation?[J]. Transplantation, 2021, 105(6): 1143-1155. DOI: 10.1097/TP.0000000000003622.
|
[21] |
HANSEN-ESTRUCH C, COOPER DKC, JUDD E. Physiological aspects of pig kidney xenotransplantation and implications for management following transplantation[J]. Xenotransplantation, 2022, 29(3): e12743. DOI: 10.1111/xen.12743.
|
[22] |
HINRICHS A, RIEDEL EO, KLYMIUK N, et al. Growth hormone receptor knockout to reduce the size of donor pigs for preclinical xenotransplantation studies[J]. Xenotransplantation, 2021, 28(2): e12664. DOI: 10.1111/xen.12664.
|
[23] |
ADAMS A, CENDALES LC, COOPER DKC, et al. American Society of Transplant Surgeons-American Society of Transplantation report of FDA meeting on regulatory expectations for xenotransplantation products[J]. Am J Transplant, 2023, 23(9): 1290-1299. DOI: 10.1016/j.ajt.2023.05.010.
|
[24] |
IWASE H, HARA H, EZZELARAB M, et al. Immunological and physiological observations in baboons with life-supporting genetically engineered pig kidney grafts[J]. Xenotransplantation, 2017, 24(2): e12293. DOI: 10.1111/xen.12293.
|
[25] |
COOPER DKC, HARA H, IWASE H, et al. Pig kidney xenotransplantation: progress toward clinical trials[J]. Clin Transplant, 2021, 35(1): e14139. DOI: 10.1111/ctr.14139.
|
[26] |
IWASE H, YAMAMOTO T, COOPER DKC. Episodes of hypovolemia/dehydration in baboons with pig kidney transplants: a new syndrome of clinical importance?[J]. Xenotransplantation, 2019, 26(2): e12472. DOI: 10.1111/xen.12472.
|
[27] |
ADAMS AB, KIM SC, MARTENS GR, et al. Xenoantigen deletion and chemical immunosuppression can prolong renal xenograft survival[J]. Ann Surg, 2018, 268(4): 564-573. DOI: 10.1097/SLA.0000000000002977.
|
[28] |
GOLDSTONE AB, BACHA EA, SYKES M. On cardiac xenotransplantation and the role of xenogeneic tolerance[J]. J Thorac Cardiovasc Surg, 2023, 166(3): 968-972. DOI: 10.1016/j.jtcvs.2022.11.036.
|
[29] |
MOHIUDDIN MM, GOERLICH CE, SINGH AK, et al. Progressive genetic modifications of porcine cardiac xenografts extend survival to 9 months[J]. Xenotransplantation, 2022, 29(3): e12744. DOI: 10.1111/xen.12744.
|
[30] |
YAMAMOTO T, LADOWSKI JM, BIKHET M, et al. Efficacy of ATG and rituximab in capuchin monkeys (a new world monkey)-an in vitro study relevant to xenotransplantation[J]. Xenotransplantation, 2020, 27(6): e12627. DOI: 10.1111/xen.12627.
|
[31] |
YAMAMOTO T, HARA H, FOOTE J, et al. Life-supporting kidney xenotransplantation from genetically engineered pigs in baboons: a comparison of two immunosuppressive regimens[J]. Transplantation, 2019, 103(10): 2090-2104. DOI: 10.1097/TP.000000000000 2796.
|
[32] |
BÜHLER L, AWWAD M, BASKER M, et al. High-dose porcine hematopoietic cell transplantation combined with CD40 ligand blockade in baboons prevents an induced anti-pig humoral response[J]. Transplantation, 2000, 69(11): 2296-2304. DOI: 10.1097/00007890-200006150-00013.
|
[33] |
TUCK N. Animals in moral limbo: how literary pigs may help lab-generated ones[J]. Animals (Basel), 2020, 10(4): 629. DOI: 10.3390/ani10040629.
|
[34] |
EL MASRI J, AFYOUNI A, GHAZI M, et al. Current state of clinical trials on xenograft[J]. Xenotransplantation, 2023, 30(3): e12801. DOI: 10.1111/xen.12801.
|
[35] |
For physicians: how to request single patient expanded access (“compassionate use”) [EB/OL]. [2023-11-01]https://www.fda.gov/drugs/investigational-new-drug-ind-application/physicians-how-request-single-patient-expanded-access-compassionate-use.
|
[36] |
SADE RM, MUKHERJEE R. Ethical issues in xenotransplantation: the first pig-to-human heart transplant[J]. Ann Thorac Surg, 2022, 113(3): 712-714. DOI: 10.1016/j.athoracsur.2022.01.006.
|
[37] |
SPILLMAN MA, SADE RM. Clinical trials of xenotransplantation: waiver of the right to withdraw from a clinical trial should be required[J]. J Law Med Ethics, 2007, 35(2): 265-272. DOI: 10.1111/j.1748-720X.2007.00135.x.
|
[38] |
杨树军,卫浩,彭江,等. 中国公众对异种肾移植接受度的预测模型构建及验证 [J]. 器官移植, 2024,15(1):102-111. DOI: 10.3969/j.issn.1674-7445.2023164.
YANG SJ, WEI H, PENG J, et al. Construction and validation of a prediction model for public acceptance of kidney xenotransplantation in China[J]. Organ Transplant, 2024,15(1):102-111. DOI: 10.3969/j.issn.1674-7445.2023164.
|
[39] |
DAS S, KOYANO-NAKAGAWA N, GAFNI O, et al. Generation of human endothelium in pig embryos deficient in ETV2[J]. Nat Biotechnol, 2020, 38(3): 297-302. DOI: 10.1038/s41587-019-0373-y.
|
[40] |
WANG J, XIE W, LI N, et al. Generation of a humanized mesonephros in pigs from induced pluripotent stem cells via embryo complementation[J]. Cell Stem Cell, 2023, 30(9): 1235-1245. DOI: 10.1016/j.stem.2023.08.003.
|
[41] |
COOPER DKC, HARA H. "You cannot stay in the laboratory forever"*: taking pig kidney xenotransplantation from the laboratory to the clinic[J]. EBioMedicine, 2021, 71: 103562. DOI: 10.1016/j.ebiom.2021.103562.
|