Research progress in liver transplantation for colorectal liver metastasis

Huang Zhongjing; Wu Ziyi; Ai Junhua

doi:10.3969/j.issn.1674-7445.2023188

Volume 15 Issue 2

Mar. 2024

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Huang Zhongjing, Wu Ziyi, Ai Junhua. Research progress in liver transplantation for colorectal liver metastasis[J]. ORGAN TRANSPLANTATION, 2024, 15(2): 185-190. doi: 10.3969/j.issn.1674-7445.2023188

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Huang Zhongjing, Wu Ziyi, Ai Junhua. Research progress in liver transplantation for colorectal liver metastasis[J]. ORGAN TRANSPLANTATION, 2024, 15(2): 185-190. doi: 10.3969/j.issn.1674-7445.2023188

Citation:

Huang Zhongjing, Wu Ziyi, Ai Junhua. Research progress in liver transplantation for colorectal liver metastasis[J]. ORGAN TRANSPLANTATION, 2024, 15(2): 185-190. doi: 10.3969/j.issn.1674-7445.2023188

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Research progress in liver transplantation for colorectal liver metastasis

doi: 10.3969/j.issn.1674-7445.2023188

Department of General Surgery, the First Affiliated Hospital of Nanchang University, Nanchang 330006, China

Funds: TENG F, SONG SH, FU ZR. Minutes of seminar on 2023 multi-center cooperation project of liver transplantation for metastatic liver cancer in China[J]. Organ Transplant, 2023, 14(4): 619-622. DOI:10.3969/j.issn.1674-7445.2023.04.021.

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Corresponding author: Ai Junhua, Email: aijh0001@163.com
Received Date: 2023-10-29
Accepted Date: 2024-01-02

Available Online: 2024-01-15

Publish Date: 2024-03-15

Abstract

Abstract

Colorectal cancer is one of the common malignant tumors in China. Studies have shown that more than 50% of patients with colorectal cancer will experience metastasis. After systematic treatment, patients with resectable colorectal cancer could obtain favorable 5-year survival rate. However, patients with unresectable colorectal liver metastasis constantly obtain poor prognosis. In spite of the development of medical treatment, patients with unresectable colorectal liver metastasis can be treated by multiple approaches, such as interventional therapy combined with targeted therapy and immunotherapy, clinical efficacy is relatively low. Hence, clinicians divert extensive attention to liver transplantation. Liver transplantation, as an emerging treatment in recent years, is expected to improve clinical prognosis of patients with unresectable colorectal liver metastasis. In this article, research progress in liver transplantation for patients with unresectable colorectal liver metastasis was reviewed, mainly including the historical overview, recent results, prognostic factors, adaptation criteria, relationship with systemic treatment, liver source shortage and donor allocation, aiming to provide reference for liver transplantation for patients with colorectal liver metastasis.
- Unresectable colorectal cancer,
- Liver metastasis,
- Liver transplantation,
- Molecular marker,
- Shortage of donor,
- Donor allocation,
- Liver transplantation criteria,
- Invasive biological behavior

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References(40)

References

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Research progress in liver transplantation for colorectal liver metastasis

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