重视供肝机械灌注研究，推动肝移植高质量发展

欧阳青; 谭晓宇; 霍枫

doi:10.3969/j.issn.1674-7445.2021.01.001

重视供肝机械灌注研究，推动肝移植高质量发展

doi: 10.3969/j.issn.1674-7445.2021.01.001

510010 广州，中国人民解放军南部战区总医院肝胆外科暨肝移植中心

基金项目:

国家自然科学基金青年项目 81800556

军队实验动物专项科研项目 SYDW（2017）12

详细信息

作者简介:
欧阳青，男，1985年生，博士，主治医师，研究方向为肝移植、器官捐献与维护，Email：kanshine@163.com

霍枫，主任医师、教授，中国人民解放军南部战区总医院普通外科首席专家、第10届中国医师奖获得者。目前担任国家人体器官捐献与移植委员会委员、全军肝胆外科专业委员会副主任委员、中国医师协会器官移植医师分会常务委员、广东省器官捐献与移植质控中心副主任、广东省医学会肝胆胰外科学分会前任主任委员、中央军委保健会诊专家。率先在国内成立了器官获取组织，开展并发表体外膜肺氧合维护供者器官的流程与规范及中国公民逝世后器官捐献的流程与规范。在机械灌注保存供者器官相关研究领域进行了大量研究，积极参与并推动了我国器官移植的改革

通讯作者:
霍枫，Email：gzhuofeng@163.com

中图分类号: R617
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出版历程
- 收稿日期: 2020-11-02
- 网络出版日期: 2021-01-19
- 刊出日期: 2021-01-19

Attaching importance to mechanical perfusion of donor liver and promoting high-quality development of liver transplantation

Department of Hepatobiliary Surgery, Liver Transplantation Center, General Hospital of Southern Theater of Chinese People's Liberation Army, Guangzhou 510010, China

More Information

Corresponding author: Huo Feng, Email: gzhuofeng@163.com

摘要

摘要: 随着器官捐献数量不断增加和扩大标准供者（ECD）供肝定义不断拓展，供肝质量必然成为影响肝移植高质量发展的突出问题，也是相关领域的研究重点。最大限度解决器官短缺和推动器官移植高质量发展是我国器官捐献与移植事业发展的方向。近年来，利用机械灌注（MP）对供肝进行灌注、保存、评估及修复，已成为当前国际上提高肝移植质量的研究热点。本文针对国内外ECD供肝的不同应用情况，结合国际上MP研究进展和本中心有关研究经验，探讨整合器官保护技术建设器官重症监护室（ICU）的可行性，拟在推动我国器官移植高质量发展同时，进一步丰富器官捐献与移植“中国模式”的技术内涵。
- 机械灌注 /
- 器官移植 /
- 肝移植 /
- 重症监护室（ICU） /
- 扩大标准供者（ECD） /
- 器官捐献 /
- 器官保护 /
- 体外膜肺氧合
Abstract: With the increasing quantity of organ donors and the continual expansion of the definition of extended criteria donor (ECD) livers, the quality of donor liver has become a prominent issue affecting the high-quality development of liver transplantation, which is also the study focus in related fields. Resolving the shortage of organs to the maximal extent and promoting the high-quality development of organ transplantation lead the development direction of organ donation and transplantation in China. In recent years, the application of mechanical perfusion (MP) for the perfusion, preservation, evaluation and repair of donor liver has become a hot topic to improve the quality of liver transplantation within the international community. In this article, according to different conditions of the application of ECD livers in liver transplantation at home and abroad in combination with the research progress on MP in the international community and relevant research experience of our center, the feasibility of establishing an organ intensive care unit (ICU) with integrated organ protection techniques was discussed, aiming to promote the high-quality development of organ transplantation in China and further expand the technical connotation of the "Chinese model" of organ donation and transplantation.
- Mechanical perfusion /
- Organ transplantation /
- Liver transplantation /
- Intensive care unit (ICU) /
- Extended criteria donor (ECD) /
- Organ donation /
- Organ protection /
- Extracorporeal membrane oxygenation

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参考文献(30)

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