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超声剪切波弹性成像在肝脏疾病中的应用进展

郑荣琴 金洁玚

郑荣琴, 金洁玚. 超声剪切波弹性成像在肝脏疾病中的应用进展[J]. 器官移植, 2017, 8(4): 260-266. doi: 10.3969/j.issn.1674-7445.2017.04.002
引用本文: 郑荣琴, 金洁玚. 超声剪切波弹性成像在肝脏疾病中的应用进展[J]. 器官移植, 2017, 8(4): 260-266. doi: 10.3969/j.issn.1674-7445.2017.04.002

超声剪切波弹性成像在肝脏疾病中的应用进展

doi: 10.3969/j.issn.1674-7445.2017.04.002
基金项目: 

国家自然科学基金 81371554

详细信息
    作者简介:

    郑荣琴, 教授, 主任医师, 博士研究生导师。现任中山大学附属第三医院超声科主任, 中山大学超声诊断与介入超声研究所副所长。兼任中国医学影像技术研究会腹部超声专业委员会主任委员、广东省医学会超声医学分会副主任委员、中国医学影像技术研究会超声分会副主任委员、中华超声医学分会委员、中国超声医师学会委员、中国超声医学工程学会介入超声专业委员会常务委员、中国医学装备协会超声装备分会常务委员、中华医学会超声医学分会介入诊疗超声组委员、中国医师协会超声医师分会介入超声专业委员会委员。兼任《器官移植》、《Liver Research》、《中华医学超声杂志(电子版)》、《中国医学影像技术》、《中国临床医学影像杂志》、《影像诊断与介入放射学杂志》、《临床超声医学杂志》编委, 《中华超声影像学杂志》特邀编委。主要从事超声诊断及介入性超声治疗工作, 特别是在超声造影新技术的临床应用、肝移植超声、肝脏纤维化超声评价、肝胆肿瘤早期诊断、超声引导肝癌射频消融等腹部超声及介入超声领域进行了深入的研究, 积累了丰富的经验。近年来在国内外专业杂志上发表学术论文310余篇, 其中SCI论文60余篇。先后主持国家自然科学基金课题、教育部及广东省科研课题14项。主编学术专著2部, 副主编及参与编写学术专著18部。申请国家发明专利10项。以第一完成人获得广东省科学技术奖二等奖、三等奖各1项, 以主要参与者获得广东省科学技术奖一等奖3项、教育部科学技术进步推广类一、二等奖各1项、广州市科学技术奖三等奖1项

    通讯作者:

    郑荣琴, Email:zhengrq@mail.sysu.edu.cn

  • 中图分类号: R617, R445.1

  • 摘要: 超声剪切波弹性成像以其无创、简便、快捷、易于掌握、可定量评估肝脏硬度等优势, 成为评估肝脏弥漫性疾病患者的肝纤维化程度、指导慢性肝病患者的治疗、预后以及随访监测的重要方法。本文就超声剪切波弹性成像的技术原理及其在肝脏的临床应用进展进行介绍。

     

  • 表  1  肝纤维化不同分期(Metavir)的TE诊断阈值

    Table  1.   Diagnostic value of TE in different stages of liver fibrosis (Metavir)

    肝病分类 TE诊断阈值(kPa) 参考文献
    F≥1 F≥2 F≥3 F=4
    慢性乙肝 6.7 7.0~8.5 8.2~8.9 11.0~14.0 [25-26]
    慢性丙肝 4.5 7.0~8.5 8.0~10.1 11.0~15.0 [18, 24, 26]
    非酒精性脂肪性肝病 5.5~7.0 6.2~11.0 8.0~12.5 9.5~16.1 [21-22, 26]
    酒精性肝病     11.6 22.7 [19]
    原发性硬化性胆管炎 7.4 8.6 09.6 14.4 [20]
    原发性胆汁性肝硬化 7.1 8.8 10.7 16.9 [23]
    下载: 导出CSV

    表  2  肝纤维化不同分期(Metavir)的2D SWE诊断阈值

    Table  2.   Diagnostic value of 2D SWE in different stages of liver fibrosis (Metavir)

    肝病分类 TE诊断阈值(kPa) 参考文献
    F≥1 F≥2 F≥3 F=4
    慢性乙肝 6.5 7.1~7.6 7.9~9.2 10.1~11.7 [25, 35]
    慢性丙肝   7.0~7.1 8.7 10.4~15.0 [18, 38]
    非酒精性脂肪性肝病   6.3~8.7 8.3~10.7 10.5~14.4 [21]
    儿童肝脏疾病 7.9 12.1 17.6 23.5 [39]
    下载: 导出CSV
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  • 收稿日期:  2017-04-28
  • 网络出版日期:  2021-01-19
  • 刊出日期:  2017-07-15

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