Application status and prospect of organ from hepatitis C donor in solid organ transplantation

Qin Zhiwen; Zhang Wu

doi:10.3969/j.issn.1674-7445.2023207

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Qin Zhiwen, Zhang Wu. Application status and prospect of organ from hepatitis C donor in solid organ transplantation[J]. ORGAN TRANSPLANTATION. doi: 10.3969/j.issn.1674-7445.2023207

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Qin Zhiwen, Zhang Wu. Application status and prospect of organ from hepatitis C donor in solid organ transplantation[J]. ORGAN TRANSPLANTATION. doi: 10.3969/j.issn.1674-7445.2023207

Citation:

Qin Zhiwen, Zhang Wu. Application status and prospect of organ from hepatitis C donor in solid organ transplantation[J]. ORGAN TRANSPLANTATION. doi: 10.3969/j.issn.1674-7445.2023207

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Application status and prospect of organ from hepatitis C donor in solid organ transplantation

doi: 10.3969/j.issn.1674-7445.2023207

Qin Zhiwen,
Zhang Wu^,

Zhejiang Chinese Medical University, Hangzhou 310000, China

More Information

Corresponding author: Zhang Wu, Email: wu.zhang@shulan.com
Received Date: 2023-12-16
Available Online: 2024-03-07

Abstract

Abstract

As a marginal organ donor, organs from hepatitis C donors have been applied in solid organ transplantation. While effectively alleviating the shortage of organs, it also faces certain challenges, such as the spread of hepatitis C virus (HCV). With the emergence and application of direct antiviral drugs, the cure of hepatitis C has gradually become a reality, laying the foundation for hepatitis C patients to become organ transplant donors. At present, with adjuvant treatment using antiviral drugs, certain efficacy has been achieved in solid organ transplantation from hepatitis C donors. In this article, research progress in kidney, heart, lung and liver transplantation from hepatitis C donors, the application of hepatitis C donors in solid organ transplantation and the safety and effectiveness of antiviral drugs were reviewed, and the feasibility of hepatitis C donors in solid organ transplantation was evaluated, aiming to provide reference for expanding the donor pool of organ transplantation and shortening the waiting time for organ transplantation in patients with end-stage diseases.
- Hepatitis C,
- Hepatitis C virus,
- Marginal donor,
- Solid organ transplantation,
- Direct-acting antiviral agent,
- Sustained virological response,
- Viremia,
- Donor shortage

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References(52)

References

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Application status and prospect of organ from hepatitis C donor in solid organ transplantation

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Application status and prospect of organ from hepatitis C donor in solid organ transplantation

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