Citation: | Peng Xuan, Ni Haiqiang, Gu Shiqi, et al. Down-regulation of XBP1s alleviates the senescence of renal tubular epithelial cells induced by hypoxia/reoxygenation through Sirt3/SOD2/mtROS signaling pathway[J]. ORGAN TRANSPLANTATION, 2024, 15(1): 46-54. doi: 10.3969/j.issn.1674-7445.2023186 |
[1] |
PONTICELLI C, REGGIANI F, MORONI G. Delayed graft function in kidney transplant: risk factors, consequences and prevention strategies[J]. J Pers Med, 2022, 12(10): 1557. DOI: 10.3390/jpm12101557.
|
[2] |
GRANATA S, VOTRICO V, SPADACCINO F, et al. Oxidative stress and ischemia/reperfusion injury in kidney transplantation: focus on ferroptosis, mitophagy and new antioxidants[J]. Antioxidants (Basel), 2022, 11(4): 769. DOI: 10.3390/antiox11040769.
|
[3] |
李晓凤, 张国欣, 杨开银, 等. 核因子E2相关因子2在肾缺血-再灌注损伤中的作用[J]. 器官移植, 2023, 14(5): 656-661. DOI: 10.3969/j.issn.1674-7445.2023124.
LI XF, ZHANG GX, YANG KY, et al. Effect of nuclear factor E2-related factor 2 on renal ischemia-reperfusion injury[J]. Organ Transplant, 2023, 14(5): 656-661. DOI: 10.3969/j.issn.1674-7445.2023124.
|
[4] |
CHEN C, ZHENG M, HOU H, et al. Cellular senescence in ischemia/reperfusion injury[J]. Cell Death Discov, 2022, 8(1): 420. DOI: 10.1038/s41420-022-01205-z.
|
[5] |
DOCHERTY MH, O'SULLIVAN ED, BONVENTRE JV, et al. Cellular senescence in the kidney[J]. J Am Soc Nephrol, 2019, 30(5): 726-736. DOI: 10.1681/ASN.2018121251.
|
[6] |
郑博文, 刘华亭, 范晓阳, 等. 肾小管上皮细胞损伤促进肾纤维化的研究进展[J]. 中国医药科学, 2023, 13(7): 54-57. DOI: 10.3969/j.issn.2095-0616.2023.07.015.
ZHENG BW, LIU HT, FAN XY, et al. Research progress of renal tubular epithelial cells injury in promoting renal fibrosis[J]. China Med Pharm, 2023, 13(7): 54-57. DOI: 10.3969/j.issn.2095-0616.2023.07.015.
|
[7] |
YAN M, SHU S, GUO C, et al. Endoplasmic reticulum stress in ischemic and nephrotoxic acute kidney injury[J]. Ann Med, 2018, 50(5): 381-390. DOI: 10.1080/07853890.2018.1489142.
|
[8] |
王立堃, 李桃, 徐芬芬. 未折叠蛋白响应的激活机制[J]. 生物化学与生物物理进展, 2023, 50(5): 877-891. DOI: 10.16476/j.pibb.2023.0137.
WANG LK, LI T, XU FF, et al. The mechanism of the unfolded protein response activation[J]. Prog Biochem Biophys, 2023, 50(5): 877-891. DOI: 10.16476/j.pibb.2023.0137.
|
[9] |
CHEN Y, BRANDIZZI F. IRE1: ER stress sensor and cell fate executor[J]. Trends Cell Biol, 2013, 23(11): 547-555. DOI: 10.1016/j.tcb.2013.06.005.
|
[10] |
PARK SM, KANG TI, SO JS. Roles of XBP1s in transcriptional regulation of target genes[J]. Biomedicines, 2021, 9(7): 791. DOI: 10.3390/biomedicines9070791.
|
[11] |
NI H, OU Z, WANG Y, et al. XBP1 modulates endoplasmic reticulum and mitochondria crosstalk via regulating NLRP3 in renal ischemia/reperfusion injury[J]. Cell Death Discov, 2023, 9(1): 69. DOI: 10.1038/s41420-023-01360-x.
|
[12] |
GAO J, FENG Z, WANG X, et al. Sirt3/SOD2 maintains osteoblast differentiation and bone formation by regulating mitochondrial stress[J]. Cell Death Differ, 2018, 25(2): 229-240. DOI: 10.1038/cdd.2017.144.
|
[13] |
TAO R, VASSILOPOULOS A, PARISIADOU L, et al. Regulation of MnSOD enzymatic activity by Sirt3 connects the mitochondrial acetylome signaling networks to aging and carcinogenesis[J]. Antioxid Redox Signal, 2014, 20(10): 1646-1654. DOI: 10.1089/ars.2013.5482.
|
[14] |
QIU X, BROWN K, HIRSCHEY MD, et al. Calorie restriction reduces oxidative stress by Sirt3-mediated SOD2 activation[J]. Cell Metab, 2010, 12(6): 662-667. DOI: 10.1016/j.cmet.2010.11.015.
|
[15] |
ZHU M, HE J, XU Y, et al. AMPK activation coupling SENP1-Sirt3 axis protects against acute kidney injury[J]. Mol Ther, 2023, 31(10): 3052-3066. DOI: 10.1016/j.ymthe.2023.08.014.
|
[16] |
ELEFTHERIADIS T, PISSAS G, FILIPPIDIS G, et al. The role of indoleamine 2, 3-dioxygenase in renal tubular epithelial cells senescence under anoxia or reoxygenation[J]. Biomolecules, 2021, 11(10): 1522. DOI: 10.3390/biom11101522.
|
[17] |
LUO C, ZHOU S, ZHOU Z, et al. Wnt9a promotes renal fibrosis by accelerating cellular senescence in tubular epithelial cells[J]. J Am Soc Nephrol, 2018, 29(4): 1238-1256. DOI: 10.1681/ASN.2017050574.
|
[18] |
VALENTIJN FA, KNOPPERT SN, MARQUEZ-EXPOSITO L, et al. Cellular communication network 2 (connective tissue growth factor) aggravates acute DNA damage and subsequent DNA damage response-senescence-fibrosis following kidney ischemia reperfusion injury[J]. Kidney Int, 2022, 102(6): 1305-1319. DOI: 10.1016/j.kint.2022.06.030.
|
[19] |
CHEN J, LU H, WANG X, et al. VNN1 contributes to the acute kidney injury-chronic kidney disease transition by promoting cellular senescence via affecting RB1 expression[J]. FASEB J, 2022, 36(9): e22472. DOI: 10.1096/fj.202200496RR.
|
[20] |
LI C, SHEN Y, HUANG L, et al. Senolytic therapy ameliorates renal fibrosis postacute kidney injury by alleviating renal senescence[J]. FASEB J, 2021, 35(1): e21229. DOI: 10.1096/fj.202001855RR.
|
[21] |
ZHANG J, ZHANG J, NI H, et al. Downregulation of XBP1 protects kidney against ischemia-reperfusion injury via suppressing HRD1-mediated NRF2 ubiquitylation[J]. Cell Death Discov, 2021, 7(1): 44. DOI: 10.1038/s41420-021-00425-z.
|
[22] |
ZHANG J, XIANG H, LIU J, et al. Mitochondrial sirtuin 3: new emerging biological function and therapeutic target[J]. Theranostics, 2020, 10(18): 8315-8342. DOI: 10.7150/thno.45922.
|
[23] |
WANG D, CAO L, ZHOU X, et al. Mitigation of honokiol on fluoride-induced mitochondrial oxidative stress, mitochondrial dysfunction, and cognitive deficits through activating AMPK/PGC-1α/Sirt3[J]. J Hazard Mater, 2022, 437: 129381. DOI: 10.1016/j.jhazmat.2022.129381.
|
[24] |
XIAO L, FANG Z, WANG Q, et al. Curcumin ameliorates age-induced tight junction impaired in porcine sertoli cells by inactivating the NLRP3 inflammasome through the AMPK/Sirt3/SOD2/mtROS signaling pathway[J]. Oxid Med Cell Longev, 2023: 1708251. DOI: 10.1155/2023/1708251.
|
[25] |
ELEFTHERIADIS T, PISSAS G, GOLFINOPOULOS S, et al. Inhibition of malate dehydrogenase-2 protects renal tubular epithelial cells from anoxia-reoxygenation-induced death or senescence[J]. Biomolecules, 2022, 12(10): 1415. DOI: 10.3390/biom12101415.
|
[26] |
QIN Z, WANG H, DOU Q, et al. Protective effect of fluoxetine against oxidative stress induced by renal ischemia-reperfusion injury via the regulation of miR-450b-5p/Nrf2 axis[J]. Aging (Albany NY), 2022,DOI: 10.18632/aging.204289[Epub ahead of print
|
[27] |
CABRAL-MIRANDA F, TAMBURINI G, MARTINEZ G, et al. Unfolded protein response IRE1/XBP1 signaling is required for healthy mammalian brain aging[J]. EMBO J, 2022, 41(22): e111952. DOI: 10.15252/embj.2022111952.
|
[28] |
HUANG C, WU S, JI H, et al. Identification of XBP1-u as a novel regulator of the MDM2/p53 axis using an shRNA library[J]. Sci Adv, 2017, 3(10): e1701383. DOI: 10.1126/sciadv.1701383.
|
[29] |
WU QJ, ZHANG TN, CHEN HH, et al. The sirtuin family in health and disease[J]. Signal Transduct Target Ther, 2022, 7(1): 402. DOI: 10.1038/s41392-022-01257-8.
|
[30] |
白玉杰, 王建辉, 吴东颖. 烟酰胺腺嘌呤二核苷酸和Sirtuins在衰老和疾病中的作用[J]. 中国生物化学与分子生物学报, 2022, 38(10): 1294-1303. DOI: 10.13865/j.cnki.cjbmb.2022.04.1562.
BAI YJ, WANG JH, WU DY. Roles of NAD+ and sirtuins in aging and disease[J]. Chin J Biochem Mol Biol, 2022, 38(10): 1294-1303. DOI: 10.13865/j.cnki.cjbmb.2022.04.1562.
|
[31] |
SUNG JY, KIM SG, KANG YJ, et al. Metformin mitigates stress-induced premature senescence by upregulating AMPKα at Ser485 phosphorylation induced Sirt3 expression and inactivating mitochondrial oxidants[J]. Mech Ageing Dev, 2022, 206: 111708. DOI: 10.1016/j.mad.2022.111708.
|
[32] |
MIAO HH, LIU Q, WANG N, et al. The effect of Sirt3/Ac-SOD2 mediated oxidative stress and HCN1 channel activity on anesthesia/surgery induced anxiety-like behavior in mice[J]. Front Med (Lausanne), 2022, 9: 783931. DOI: 10.3389/fmed.2022.783931.
|
[33] |
刘恋, 夏中元, 李冰玉, 等. Sirt3过表达对高糖小鼠海马神经元缺氧复氧损伤的影响: 与SOD2的关系[J]. 中华麻醉学杂志, 2021, 41(5): 621-624. DOI: 10.3760/cma.j.cn131073.20210312.00526.
LIU L, XIA ZY, LI BY, et al. Effect of Sirt3 overexpression on hypoxia-reoxygenation injury to hippocampal neurons of mice exposed to high glucose: relationship with SOD2[J]. Chin J Anesthesiol, 2021, 41(5): 621-624. DOI: 10.3760/cma.j.cn131073.20210312.00526.
|
[34] |
MA LL, KONG FJ, DONG Z, et al. Hypertrophic preconditioning attenuates myocardial ischaemia-reperfusion injury by modulating Sirt3-SOD2-mROS-dependent autophagy[J]. Cell Prolif, 2021, 54(7): e13051. DOI: 10.1111/cpr.13051.
|
[35] |
NING L, RUI X, GUORUI L, et al. A novel mechanism for the protection against acute lung injury by melatonin: mitochondrial quality control of lung epithelial cells is preserved through Sirt3-dependent deacetylation of SOD2[J]. Cell Mol Life Sci, 2022, 79(12): 610. DOI: 10.1007/s00018-022-04628-0.
|
[36] |
CHEN ML, ZHU XH, RAN L, et al. Trimethylamine-N-oxide induces vascular inflammation by activating the NLRP3 inflammasome through the Sirt3-SOD2-mtROS signaling pathway[J]. J Am Heart Assoc, 2017, 6(9): e006347. DOI: 10.1161/JAHA.117.006347.
|
[37] |
PI H, XU S, REITER RJ, et al. Sirt3-SOD2-mROS-dependent autophagy in cadmium-induced hepatotoxicity and salvage by melatonin[J]. Autophagy, 2015, 11(7): 1037-1051. DOI: 10.1080/15548627.2015.1052208.
|
[38] |
LI Q, LIAO J, CHEN W, et al. NAC alleviative ferroptosis in diabetic nephropathy via maintaining mitochondrial redox homeostasis through activating Sirt3-SOD2/Gpx4 pathway[J]. Free Radic Biol Med, 2022, 187: 158-170. DOI: 10.1016/j.freeradbiomed.2022.05.024.
|