Research progress on anhepatic phase in rat liver transplantation

Han Tian; Zhang Li; Chang Qingyao; Li Xiang; He Xiaopeng; Yan Zhening; Gao Lin; Xu Jun

doi:10.3969/j.issn.1674-7445.2023.01.019

Volume 14 Issue 1

Jan. 2023

Turn off MathJax

Article Contents

Article Navigation > ORGAN TRANSPLANTATION > 2023 > 14(1): 142-146

Han Tian, Zhang Li, Chang Qingyao, et al. Research progress on anhepatic phase in rat liver transplantation[J]. ORGAN TRANSPLANTATION, 2023, 14(1): 142-146. doi: 10.3969/j.issn.1674-7445.2023.01.019

Citation:

Han Tian, Zhang Li, Chang Qingyao, et al. Research progress on anhepatic phase in rat liver transplantation[J]. ORGAN TRANSPLANTATION, 2023, 14(1): 142-146. doi: 10.3969/j.issn.1674-7445.2023.01.019

Citation:

Han Tian, Zhang Li, Chang Qingyao, et al. Research progress on anhepatic phase in rat liver transplantation[J]. ORGAN TRANSPLANTATION, 2023, 14(1): 142-146. doi: 10.3969/j.issn.1674-7445.2023.01.019

PDF( 1353 KB)

Research progress on anhepatic phase in rat liver transplantation

doi: 10.3969/j.issn.1674-7445.2023.01.019

Department of Hepatobiliary and Pancreatic Surgery, Liver Transplantation Center, the First Hospital of Shanxi Medical University, Taiyuan 030001, China

More Information

Corresponding author: Xu Jun, Email: junxuty@163.com
Received Date: 2022-09-11
Available Online: 2023-01-17
Publish Date: 2023-01-15

Abstract

Abstract

With persistent advancement of surgical instruments, methods and techniques, clinical efficacy of liver transplantation has been steadily enhanced. However, the length of anhepatic phase is still an important factor affecting the efficacy of liver transplantation. Rat is one of the major animal models for liver transplantation-related basic research. In this article, multiple approaches for prolonging the anhepatic phase and shortening the operation time during anhepatic phase in rat liver transplantation were reviewed, which consisted of sevoflurane inhalation anesthesia, intravenous infusion via jugular vein indwelling needle, clamping of the abdominal aorta before anhepatic phase, injection of normal saline into portal vein before anhepatic phase, subcutaneous transposition of the spleen, electrocoagulation of hepatic esophageal artery, magnetic ring anastomosis of the superior and inferior hepatic vena cava, cannula anastomosis of the superior and inferior hepatic vena cava, stent anastomosis of the superior and inferior hepatic vena cava, rapid connection device and cannula of portal vein, and ring-shaped cannula of hepatic tissue-preserving inferior hepatic vena cava, aiming to add evidence for prolonging the duration of anhepatic phase, improving the operation efficiency during anhepatic phase and elevating the success rate of rat liver transplantation.
- Rat,
- Liver transplantation,
- Anhepatic phase,
- Inferior vena cava,
- Portal vein,
- Fluid infusion,
- Magnetic ring anastomosis,
- Stent anastomosis,
- Cannula anastomosis

FullText(HTML)

References(34)

References

[1]	CHENG Y, LAN H, CHEN Y, et al. Protective effect of retrograde reperfusion against hepatic autophagy impairment in rat liver transplantation[J]. Transplant Proc, 2021, 53(1): 443-449. DOI: 10.1016/j.transproceed.2020.10.010.
[2]	VANDERMEULEN M, ERPICUM P, BLETARD N, et al. Effect of the combination of everolimus and mesenchymal stromal cells on regulatory T cells levels and in a liver transplant rejection model in rats[J]. Front Immunol, 2022, 13: 877953. DOI: 10.3389/fimmu.2022.877953.
[3]	YUAN M, LIN L, CAO H, et al. Intestinal microbiota participates in the protective effect of HO-1/BMMSCs on liver transplantation with steatotic liver grafts in rats[J]. Front Microbiol, 2022, 13: 905567. DOI: 10.3389/fmicb.2022.905567.
[4]	WU W, WANG M, LI C, et al. LncRNA Snhg1 plays an important role via sequestering rno-miR-139-5p to function as a ceRNA in acute rejection after rat liver transplantation based on the bioinformatics analysis[J]. Front Genet, 2022, 13: 827193. DOI: 10.3389/fgene.2022.827193.
[5]	张继翔, 闫宏宪, 轩娟娟, 等. 门脉优先反向吻合快速建立肝移植大鼠模型[J]. 中国组织工程研究, 2022, 26(17): 2696-2701. https://www.cnki.com.cn/Article/CJFDTOTAL-XDKF202217013.htm ZHANG JX, YAN HX, XUAN JJ, et al. Rapid establishment of rat liver transplantation model by portal vein preferential reverse anastomosis[J]. Chin J Tissue Eng Res, 2022, 26(17): 2696-2701. https://www.cnki.com.cn/Article/CJFDTOTAL-XDKF202217013.htm
[6]	沃琪, 任咪, 李蕾, 等. 大鼠肝移植肝上下腔静脉不同缝合方式及手术体会[J]. 现代生物医学进展, 2021, 21(4): 609-613. DOI: 10.13241/j.cnki.pmb.2021.04.002. WO Q, REN M, LI L, et al. Different suture technique of suprahepatic vena cava and corresponding surgical experience in rat liver transplantation[J]. Prog Mod Biomed, 2021, 21(4): 609-613. DOI: 10.13241/j.cnki.pmb.2021.04.002.
[7]	李蕾, 李善宝, 汪涛, 等. 单人直视下大鼠肝移植模型供肝获取不同灌注方式比较[J]. 器官移植, 2020, 11(3): 356-361. DOI: 10.3969/j.issn.1674-7445.2020.03.006. LI L, LI SB, WANG T, et al. Comparison between different perfusion methods for donor liver acquisition in rat liver transplantation model under direct vision of single operator[J]. Organ Transplant, 2020, 11(3): 356-361. DOI: 10.3969/j.issn.1674-7445.2020.03.006.
[8]	QU B, YU F, SHENG GN, et al. Protective effect of a novel technique for liver transplantation in the rat[J]. Transplant Proc, 2018, 50(1): 267-273. DOI: 10.1016/j.transproceed.2017.12.020.
[9]	YUAN Y, CHEN MH, HUANG J, et al. Organ ischemia-reperfusion injury by simulating hemodynamic changes in rat liver transplant model[J]. J Vis Exp, 2021(169): e61779. DOI: 10.3791/61779.
[10]	HORI T, NGUYEN JH, ZHAO X, et al. Comprehensive and innovative techniques for liver transplantation in rats: a surgical guide[J]. World J Gastroenterol, 2010, 16(25): 3120-3132. DOI: 10.3748/wjg.v16.i25.3120.
[11]	OLDANI G, LACOTTE S, MOREL P, et al. Orthotopic liver transplantation in rats[J]. J Vis Exp, 2012(65): 4143. DOI: 10.3791/4143.
[12]	ROMERO-ÁVILA P, MÁRQUEZ-ESPINÓS C, CABRERA AFONSO JR. Historical development of the anesthetic machine: from Morton to the integration of the mechanical ventilator[J]. Braz J Anesthesiol, 2021, 71(2): 148-161. DOI: 10.1016/j.bjane.2021.02.017.
[13]	ZHANG K, XU X, HU L. Sevoflurane attenuates hepatic ischemia reperfusion injury by the miR-122/Nrf2 pathway[J]. Ann Transl Med, 2022, 10(6): 350. DOI: 10.21037/atm-22-115.
[14]	CHEN JL, CHEN YL, QI B, et al. Impact of intraoperative norepinephrine support on living donor liver transplantation outcomes: a retrospective cohort study of 430 children[J]. Front Pharmacol, 2020, 11: 1254. DOI: 10.3389/fphar.2020.01254.
[15]	XU HS, ROSENLOF LK, PRUETT TL, et al. Prostaglandin E1 increases survival with extended anhepatic phase during liver transplantation[J]. Ann Surg, 1994, 220(1): 53-58. DOI: 10.1097/00000658-199407000-00009.
[16]	TOURKY MS, SALMAN AA, SALMAN MA, et al. Intraoperative factors associated with early recipient death after adult-to-adult living donor liver transplant[J]. Exp Clin Transplant, 2021, 19(8): 817-825. DOI: 10.6002/ect.2021.0084.
[17]	YOSHIDA K, KUWANA K, HONDA J, et al. Administration of sodium bicarbonate in pediatric liver transplantation can also confirm intravenous position of catheters[J]. Paediatr Anaesth, 2022, 32(12): 1374-1375. DOI: 10.1111/pan.14542.
[18]	JIANG H, LIU J, XU Z, et al. Efficacy of different fluid resuscitation methods on coagulation function of rats with traumatic hemorrhagic shock[J]. J Surg Res, 2021, 260: 259-266. DOI: 10.1016/j.jss.2020.11.014.
[19]	XU L, LI L, ZU J, et al. Effects of different types of early restrictive fluid resuscitation on immune function and multiorgan damage on hemorrhagic shock rat model in a hypothermic environment[J]. Comput Math Methods Med, 2022: 4982047. DOI: 10.1155/2022/4982047.
[20]	TING WT, CHANG RW, WANG CH, et al. Comparison of the trometamol-balanced solution with two other crystalloid solutions for fluid resuscitation of a rat hemorrhagic model[J]. J Vet Sci, 2020, 21(1): e6. DOI: 10.4142/jvs.2020.21.e6.
[21]	LIU C, TSAI HL, CHIN T, et al. Clamping the supra-celiac aorta can effectively increase the success rate of orthotopic rat liver transplantation by increasing the tolerable time of the anhepatic phase[J]. J Surg Res, 2006, 136(1): 116-119. DOI: 10.1016/j.jss.2006.05.011.
[22]	ELCHANINOV A, VISHNYAKOVA P, SUKHIKH G, et al. Spleen: reparative regeneration and influence on liver[J]. Life (Basel), 2022, 12(5): 626. DOI: 10.3390/life12050626.
[23]	BENGMARK S, BÖRJESSON B, OLIN T. Development of portasystemic shunts after subcutaneous transposition of the spleen in the rat[J]. Am J Surg, 1973, 125(6): 757-762. DOI: 10.1016/0002-9610(73)90179-7.
[24]	USHIMARU Y, ODAGIRI K, AKEO K, et al. Efficacy of electrocoagulation hemostasis: a study on the optimal usage of the very-low-voltage mode[J]. Surg Endosc, 2022, 36(11): 8592-8599. DOI: 10.1007/s00464-022-09492-4.
[25]	OLASEHINDE O, OWOJUYIGBE A, ADEYEMO A, et al. Use of energy device in general surgical operations: impact on peri-operative outcomes[J]. BMC Surg, 2022, 22(1): 90. DOI: 10.1186/s12893-022-01540-z.
[26]	YANG L, LU J, WANG Y, et al. A rat model of orthotopic liver transplantation using a novel magnetic anastomosis technique for suprahepatic vena cava reconstruction[J]. J Vis Exp, 2018(133): 56933. DOI: 10.3791/56933.
[27]	SHI Y, ZHANG W, DENG YL, et al. Magnetic ring anastomosis of suprahepatic vena cava: novel technique for liver transplantation in rat[J]. Transpl Int, 2015, 28(1): 89-94. DOI: 10.1111/tri.12418.
[28]	MIYATA M, FISCHER JH, FUHS M, et al. A simple method for orthotopic liver transplantation in the rat. cuff technique for three vascular anastomoses[J]. Transplantation, 1980, 30(5): 335-338. DOI: 10.1097/00007890-198011000-00005.
[29]	SETTAF A, GUGENHEIM J, HOUSSIN D, et al. Cuff technique for orthotopic liver transplantation in the rat. a simplified method for the suprahepatic vena cava anastomosis[J]. Transplantation, 1986, 42(3): 330-331. doi: 10.1097/00007890-198609000-00027
[30]	TSUCHIMOTO S, KUSUMOTO K, NAKAJIMA Y, et al. Orthotopic liver transplantation in the rat. a simplified technique using the cuff method for suprahepatic vena cava anastomosis[J]. Transplantation, 1988, 45(6): 1153-1155. doi: 10.1097/00007890-198806000-00036
[31]	HARIHARA Y, SANJO K, IDEZUKI Y. A modified cuff technique for suprahepatic vena cava anastomosis in rat liver transplantation[J]. Transplantation, 1992, 53(3): 707-709.
[32]	OLDANI G, MAESTRI M, GASPARI A, et al. A novel technique for rat liver transplantation using Quick Linker system: a preliminary result[J]. J Surg Res, 2008, 149(2): 303-309. DOI: 10.1016/j.jss.2007.12.779.
[33]	TAN F, CHEN Z, ZHAO Y, et al. Novel technique for suprahepatic vena cava reconstruction in rat orthotopic liver transplantation[J]. Microsurgery, 2005, 25(7): 556-560. DOI: 10.1002/micr.20161.
[34]	WANG H, LI C, HU J, et al. Effect of different suprahepatic vena cava reconstruction methods on the hemodynamics of rats after liver transplantation[J]. PLoS One, 2013, 8(9): e72695. DOI: 10.1371/journal.pone.0072695.

Relative Articles

Supplements(0)

Cited By

Proportional views

Proportional views

通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142

Figures(1)

Get Citation

PDF

XML

Article Metrics

Article views (236) PDF downloads(76)

Research progress on anhepatic phase in rat liver transplantation

doi: 10.3969/j.issn.1674-7445.2023.01.019

Abstract

References

Proportional views

Catalog

通讯作者: 陈斌, bchen63@163.com

Article Metrics

Proportional views

Related

Research progress on anhepatic phase in rat liver transplantation

doi: 10.3969/j.issn.1674-7445.2023.01.019

Abstract

References

Proportional views

Catalog

通讯作者: 陈斌, bchen63@163.com

Article Metrics

Proportional views

Related

Export File

Citation

Format

Content