Volume 13 Issue 5
Sep.  2022
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Fu Xiaona, Zhang Li, Wang Jing. Imaging manifestations of central nervous system complications after heart transplantation[J]. ORGAN TRANSPLANTATION, 2022, 13(5): 672-677. doi: 10.3969/j.issn.1674-7445.2022.05.019
Citation: Fu Xiaona, Zhang Li, Wang Jing. Imaging manifestations of central nervous system complications after heart transplantation[J]. ORGAN TRANSPLANTATION, 2022, 13(5): 672-677. doi: 10.3969/j.issn.1674-7445.2022.05.019

Imaging manifestations of central nervous system complications after heart transplantation

doi: 10.3969/j.issn.1674-7445.2022.05.019
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  • Corresponding author: Wang Jing, Email: xhwangjing@hust.edu.cn
  • Received Date: 2022-04-23
    Available Online: 2022-09-14
  • Publish Date: 2022-09-15
  • Heart transplantation is the main treatment of end-stage heart failure. With the advancement of heart transplantation and rational use of postoperative immunosuppressants, the survival rate of recipients has been gradually enhanced. However, a variety of central nervous system complications may still occur following heart transplantation, including immunosuppressant-associated neurotoxicity, epilepsy, stroke, encephalopathy, central nervous system infection and de novo malignant tumors in the central nervous system. These complications will severely affect the quality of life of heart transplant recipients. Consequently, prompt imaging diagnosis plays a significant role in the prevention and treatment of central nervous system complications. In this article, main imaging manifestations of central nervous system complications after heart transplantation were reviewed, aiming to provide reference for prompt diagnosis and differential diagnosis of complications, guide clinical treatment and management, and improve the long-term prognosis of the recipients.

     

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  • [1]
    顾敏, 廖中凯, 石丽, 等. 心脏移植术后神经系统并发症研究进展[J/CD]. 中华移植杂志(电子版), 2020, 14(4): 255-257. DOI: 10.3877/cma.j.issn.1674-3903.2020.04.014.

    GU M, LIAO ZK, SHI L, et al. Research progress of neurologic complications after heart transplantation[J/CD]. Chin J Transplant(Electr Edit), 2020, 14(4): 255-257. DOI: 10.3877/cma.j.issn.1674-3903.2020.04.014.
    [2]
    中华医学会器官移植学分会. 器官移植免疫抑制剂临床应用技术规范(2019版)[J]. 器官移植, 2019, 10(3): 213-226. DOI: 10.3969/j.issn.1674-7445.2019.03.001.

    Branch of Organ Transplantation of Chinese Medical Association. Technical specification for clinical application of immunosuppressive agents in organ transplantation (2019 edition)[J]. Organ Transplant, 2019, 10(3): 213-226. DOI: 10.3969/j.issn.1674-7445.2019.03.001.
    [3]
    GEWIRTZ AN, GAO V, PARAUDA SC, et al. Posterior reversible encephalopathy syndrome[J]. Curr Pain Headache Rep, 2021, 25(3): 19. DOI: 10.1007/s11916-020-00932-1.
    [4]
    RAMIREZ R, MUSKULA PR, EVERLEY MP. Posterior reversible encephalopathy syndrome after orthotopic heart transplantation: a case report[J]. Am J Case Rep, 2017, 18: 487-490. DOI: 10.12659/ajcr.903403.
    [5]
    PARASHER A, JHAMB R. Posterior reversible encephalopathy syndrome (PRES): presentation, diagnosis and treatment[J]. Postgrad Med J, 2020, 96(1140): 623-628. DOI: 10.1136/postgradmedj-2020-137706.
    [6]
    LIN P, TIAN X, WANG X. Seizures after transplantation[J]. Seizure, 2018, 61: 177-185. DOI: 10.1016/j.seizure.2018.08.010.
    [7]
    BRAVO P, VADDIPARTI A, HIRSCH LJ. Pharmacotherapy for nonconvulsive seizures and nonconvulsive status epilepticus[J]. Drugs, 2021, 81(7): 749-770. DOI: 10.1007/s40265-021-01502-4.
    [8]
    QUBTY W, IRWIN SL, FOX CK. Review on the diagnosis and treatment of reversible cerebral vasoconstriction syndrome in children and adolescents[J]. Semin Neurol, 2020, 40(3): 294-302. DOI: 10.1055/s-0040-1702942.
    [9]
    RINDLER RS, ALLEN JW, BARROW JW, et al. Neuroimaging of intracerebral hemorrhage[J]. Neurosurgery, 2020, 86(5): E414-E423. DOI: 10.1093/neuros/nyaa029.
    [10]
    MERKLER AE, CHEN ML, PARIKH NS, et al. Association between heart transplantation and subsequent risk of stroke among patients with heart failure[J]. Stroke, 2019, 50(3): 583-587. DOI: 10.1161/STROKEAHA.118.023622.
    [11]
    ACAMPA M, LAZZERINI PE, GUIDERI F, et al. Ischemic stroke after heart transplantation[J]. J Stroke, 2016, 18(2): 157-168. DOI: 10.5853/jos.2015.01599.
    [12]
    WU X, ZOU Y, YOU S, et al. Distribution of risk factors of ischemic stroke in Chinese young adults and its correlation with prognosis[J]. BMC Neurol, 2022, 22(1): 26. DOI: 10.1186/s12883-022-02552-1.
    [13]
    JADHAV AP, DESAI SM, LIEBESKIND DS, et al. Neuroimaging of acute stroke[J]. Neurol Clin, 2020, 38(1): 185-199. DOI: 10.1016/j.ncl.2019.09.004.
    [14]
    黄光. 心源性卒中的病因和风险[J]. 中国卒中杂志, 2019, 14(5): 410-413. DOI: 10.3969/j.issn.1673-5765.2019.05.002.

    HUANG G. Causes and risks of cardic stroke[J]. Chin J Stroke, 2019, 14(5): 410-413. DOI: 10.3969/j.issn.1673-5765.2019.05.002.
    [15]
    唐铁钰, 刘一辉, 蔡玉建, 等. 分水岭脑梗死的临床和影像学特点[J/CD]. 中华临床医师杂志(电子版), 2013, 7(2): 829-831. DOI: 10.3877/cma.j.issn.1674-0785.2013.02.070.

    TANG TY, LIU YH, CAI YJ, et al. Clinical and imaging features of watershed cerebral infarction[J/CD]. Chin J Clin(Electr Edit), 2013, 7(2): 829-831. DOI: 10.3877/cma.j.issn.1674-0785.2013.02.070.
    [16]
    ACAMPA M, LAZZERINI PE, GUIDERI F, et al. Homocysteine and P wave dispersion in patients with heart transplantation[J]. Clin Transplant, 2011, 25(1): 119-125. DOI: 10.1111/j.1399-0012.2009.01126.x.
    [17]
    CHAI S, SHENG Z, XIE W, et al. Assessment of apparent internal carotid tandem occlusion on high-resolution vessel wall imaging: comparison with digital subtraction angiography[J]. AJNR Am J Neuroradiol, 2020, 41(4): 693-699. DOI: 10.3174/ajnr.A6452.
    [18]
    GONG Y, CAO C, GUO Y, et al. Quantification of intracranial arterial stenotic degree evaluated by high-resolution vessel wall imaging and time-of-flight MR angiography: reproducibility, and diagnostic agreement with DSA[J]. Eur Radiol, 2021, 31(8): 5479-5489. DOI: 10.1007/s00330-021-07719-x.
    [19]
    SHI Z, TIAN X, TIAN B, et al. Identification of high risk clinical and imaging features for intracranial artery dissection using high-resolution cardiovascular magnetic resonance[J]. J Cardiovasc Magn Reson, 2021, 23(1): 74. DOI: 10.1186/s12968-021-00766-9.
    [20]
    SAKUSIC A, RABINSTEIN AA. Neurological complications in patients with heart transplantation[J]. Semin Neurol, 2021, 41(4): 447-452. DOI: 10.1055/s-0041-1726285.
    [21]
    PILATO F, DISTEFANO M, CALANDRELLI R. Posterior reversible encephalopathy syndrome and reversible cerebral vasoconstriction syndrome: clinical and radiological considerations[J]. Front Neurol, 2020, 11: 34. DOI: 10.3389/fneur.2020.00034.
    [22]
    BALDASSARI LE, WATTJES MP, CORTESE I, et al. The neuroradiology of progressive multifocal leukoencephalopathy: a clinical trial perspective[J]. Brain, 2022, 145(2): 426-440. DOI: 10.1093/brain/awab419.
    [23]
    LV X, HONG Q, LIN X, et al. Osmotic demyelination syndrome: clinical, neuroimaging characteristics, and outcomes in a series of 18 cases[J]. Biomed Res Int, 2021, 2021: 9944632. DOI: 10.1155/2021/9944632.
    [24]
    SENZOLO M, FERRONATO C, BURRA P. Neurologic complications after solid organ transplantation[J]. Transpl Int, 2009, 22(3): 269-278. DOI: 10.1111/j.1432-2277.2008.00780.x.
    [25]
    CHEN F, ZHAO Y, SHEN C, et al. Next generation sequencing for diagnosis of central nervous system aspergillosis in liver transplant recipients[J]. Ann Transl Med, 2021, 9(13): 1071. DOI: 10.21037/atm-21-92.
    [26]
    ARSLAN F, ERTAN G, EMECEN AN, et al. Clinical presentation and cranial MRI findings of listeria monocytogenes encephalitis: a literature review of case series[J]. Neurologist, 2018, 23(6): 198-203. DOI: 10.1097/NRL.0000000000000212.
    [27]
    SMITH JD, STOWELL JT, MARTÍNEZ-JIMÉNEZ S, et al. Evaluation after orthotopic heart transplant: what the radiologist should know[J]. Radiographics, 2019, 39(2): 321-343. DOI: 10.1148/rg.2019180141.
    [28]
    WHITE ML, MOORE DW, ZHANG Y, et al. Primary central nervous system post-transplant lymphoproliferative disorders: the spectrum of imaging appearances and differential[J]. Insights Imaging, 2019, 10(1): 46. DOI: 10.1186/s13244-019-0726-6.
    [29]
    YOUN JC, STEHLIK J, WILK AR, et al. Temporal trends of de novo malignancy development after heart transplantation[J]. J Am Coll Cardiol, 2018, 71(1): 40-49. DOI: 10.1016/j.jacc.2017.10.077.
    [30]
    STEHLIK J, KOBASHIGAWA J, HUNT SA, et al. Honoring 50 years of clinical heart transplantation in circulation: in-depth state-of-the-art review[J]. Circulation, 2018, 137(1): 71-87. DOI: 10.1161/CIRCULATIONAHA.117.029753.
    [31]
    ASLEH R, ALNSASRA H, HABERMANN TM, et al. Post-transplant lymphoproliferative disorder following cardiac transplantation[J]. Front Cardiovasc Med, 2022, 9: 787975. DOI: 10.3389/fcvm.2022.787975.
    [32]
    TAN AC, ASHLEY DM, LÓPEZ GY, et al. Management of glioblastoma: state of the art and future directions[J]. CA Cancer J Clin, 2020, 70(4): 299-312. DOI: 10.3322/caac.21613.
    [33]
    张君, 马林. 重视高分辨率MRI新技术对颅内血管壁病变的研究[J]. 中华放射学杂志, 2020, 54(4): 269-270. DOI: 10.3760/cma.j.cn112149-20200207-00109.

    ZHANG J, MA L. Attaching importance to the research of vessel wall MRI in cerebrovascular disorders[J]. Chin J Radiol, 2020, 54(4): 269-270. DOI: 10.3760/cma.j.cn112149-20200207-00109.
    [34]
    中华医学会器官移植学分会. 中国心脏移植术后随访技术规范(2019版)[J/CD]. 中华移植杂志(电子版), 2019, 13(1): 24-27. DOI: 10.3877/cma.j.issn1674-3903.2019.01.006.

    Branch of Organ Transplantation of Chinese Medical Association. Technical specifications for follow-up after heart transplantation in China (2019 edition)[J/CD]. Chin J Transplant(Electr Edit), 2019, 13(1): 24-27. DOI: 10.3877/cma.j.issn1674-3903.2019.01.006.
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