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Zhang Yinsheng, Peng Xingtong, Yang Tingkai, et al. Recurrence of IgA nephropathy after kidney transplantation[J]. ORGAN TRANSPLANTATION, 2022, 13(5): 583-590. doi: 10.3969/j.issn.1674-7445.2022.05.006
Citation: Zhang Yinsheng, Peng Xingtong, Yang Tingkai, et al. Recurrence of IgA nephropathy after kidney transplantation[J]. ORGAN TRANSPLANTATION, 2022, 13(5): 583-590. doi: 10.3969/j.issn.1674-7445.2022.05.006
shu

Recurrence of IgA nephropathy after kidney transplantation

doi: 10.3969/j.issn.1674-7445.2022.05.006

  • Department of Urology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing 100730, China

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  • Corresponding author: Wen Jin, Email: wjpumch@163.com; Ji Zhigang, Email: jzgjxmc@163.com
  • Received Date: 2022-04-22
    Available Online: 2022-09-14
  • Publish Date: 2022-09-15
    Abstract
  • IgA nephropathy (IgAN) is one of the common primary glomerulonephritis, which is also an important risk factor for end-stage renal disease. Kidney transplantation is the optimal treatment for end-stage renal disease induced by IgAN, whereas there is still a risk of recurrence of IgAN after kidney transplantation. At present, research progress upon IgAN recurrence after kidney transplantation is relatively lacking. The pathogenesis of IgAN recurrence remains elusive, and its pathological manifestations are not specific. The diagnosis of IgAN recurrence still depends on renal biopsy. Besides, no effective prevention and treatment are available for recurrent IgAN. In this article, research progress on IgAN recurrence after kidney transplantation was illustrated from the perspectives of pathogenesis, diagnosis, risk factors and treatment, aiming to provide reference for clinical prevention and treatment of IgAN recurrence after kidney transplantation and improve clinical prognosis of kidney transplant recipients.

     

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