Volume 13 Issue 5
Sep.  2022
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Transplantation Immunology Committee of Branch of Organ Transplantation Physician of Chinese Medical Doctor Association, Organ Transplant Rehabilitation Committee of China Association Rehabilitation Medicine, Branch of Organ Transplantation Physician of Guangdong Medical Doctor Association. Expert consensus on liver transplantation perioperative evaluation and rehabilitation for acute-on-chronic liver failure[J]. ORGAN TRANSPLANTATION, 2022, 13(5): 543-554. doi: 10.3969/j.issn.1674-7445.2022.05.001
Citation: Transplantation Immunology Committee of Branch of Organ Transplantation Physician of Chinese Medical Doctor Association, Organ Transplant Rehabilitation Committee of China Association Rehabilitation Medicine, Branch of Organ Transplantation Physician of Guangdong Medical Doctor Association. Expert consensus on liver transplantation perioperative evaluation and rehabilitation for acute-on-chronic liver failure[J]. ORGAN TRANSPLANTATION, 2022, 13(5): 543-554. doi: 10.3969/j.issn.1674-7445.2022.05.001
shu

Expert consensus on liver transplantation perioperative evaluation and rehabilitation for acute-on-chronic liver failure

doi: 10.3969/j.issn.1674-7445.2022.05.001

  • Surgical Intensive Care Unit, Intensive Care Unit of Organ Transplantation, the Third Affiliated Hospital of Sun Yat-sen University, Guangzhou 510630, China

  • Received Date: 2022-07-18
    Available Online: 2022-09-14
  • Publish Date: 2022-09-15
    Abstract
  • Acute-on-chronic liver failure (ACLF) can be cured by liver transplantation; however, perioperative complications still affect posttransplant outcomes. In recent years, early rehabilitation for critical illness, liver disease, and surgery have significantly improved organ reserve function, surgery tolerance, and postoperative quality of life. They could also be applied in the perioperative period of liver transplantation in patients with ACLF. Therefore, the Transplantation Immunology Committee of Branch of Organ Transplantation Physician of Chinese Medical Doctor Association, the Organ Transplant Rehabilitation Committee of China Association Rehabilitation Medicine, and the Branch of Organ Transplantation Physician of Guangdong Medical Doctor Association conducted a comprehensive review of rehabilitation in end-stage liver disease, critical illness and surgical patients by summarizing current evidence and best clinical practices and proposed a practice consensus on evaluation of cardiopulmonary and physical function, rehabilitation or physiotherapies, as well as the safety concerns in perioperative liver transplant recipients. It will be a valuable resource for hepatologists, transplant surgeons, and intensivists as they care for ACLF patients during transplantation.

     

    • Corresponding authors: Yi Huimin, Email: ylhmin@hotmail.com
    Yang Yang, Email: yysysu@163.com
    Hu Xiquan, Email: huxiquan@mail.sysu.edu.cn
    Chen Guihua, Email: chgh1955@263.net
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  • [1]
    BRUSTIA R, MONSEL A, SKURZAK S, et al. Guidelines for perioperative care for liver transplantation: enhanced recovery after surgery (ERAS) recommendations[J]. Transplantation, 2022, 106(3): 552-561. DOI: 10.1097/TP.0000000000003808.
    [2]
    MELLOUL E, HÜBNER M, SCOTT M, et al. Guidelines for perioperative care for liver surgery: enhanced recovery after surgery (ERAS) society recommendations[J]. World J Surg, 2016, 40(10): 2425-2440. DOI: 10.1007/s00268-016-3700-1.
    [3]
    KRASNOFF JB, VINTRO AQ, ASCHER NL, et al. A randomized trial of exercise and dietary counseling after liver transplantation[J]. Am J Transplant, 2006, 6(8): 1896-1905. DOI: 10.1111/j.1600-6143.2006.01391.x.
    [4]
    TOMÁS MT, SANTA-CLARA H, BRUNO PM, et al. The impact of exercise training on liver transplanted familial amyloidotic polyneuropathy (FAP) patients[J]. Transplantation, 2013, 95(2): 372-377. DOI: 10.1097/TP.0b013e31827220e7.
    [5]
    MAFFEI P, WIRAMUS S, BENSOUSSAN L, et al. Intensive early rehabilitation in the intensive care unit for liver transplant recipients: a randomized controlled trial[J]. Arch Phys Med Rehabi, 2017, 98(8): 1518-1525. DOI: 10.1016/j.apmr.2017.01.028.
    [6]
    Transplantation Immunology Committee of Branch of Organ Transplantation Physician of Chinese Medical Doctor Association, Enhanced Recovery of Liver Transplantation Group of Enhanced Recovery after Surgery Committee of Chinese Research Hospital Society. Expert consensus on perioperative management of liver transplantation in adults with acute-on-chronic liver failure[J]. Liver Res, 2021, 5(2): 37-44. DOI: 10.1016/j.livres.2021.03.002.
    [7]
    HARBOUR R, MILLER J. A new system for grading recommendations in evidence based guidelines[J]. BMJ, 2001, 323(7308): 334-336. DOI: 10.1136/bmj.323.7308.334.
    [8]
    BRUSTIA R, BOLESLAWSKI E, MONSEL A, et al. Definition and prospective assessment of functional recovery after liver transplantation: a new objective consensus-based metric for safe discharge[J]. Liver Transpl, 2020, 26(10): 1241-1253. DOI: 10.1002/lt.25841.
    [9]
    DUNN MA, ROGAL SS, DUARTE-ROJO A, et al. Physical function, physical activity, and quality of life after liver transplantation[J]. Liver Transpl, 2020, 26(5): 702-708. DOI: 10.1002/lt.25742.
    [10]
    MARTIN P, DIMARTINI A, FENG S, et al. Evaluation for liver transplantation in adults: 2013 practice guideline by the American Association for the Study of Liver Diseases and the American Society of Transplantation[J]. Hepatology, 2014, 59(3): 1144-1165. DOI: 10.1002/hep.26972.
    [11]
    YAO EH, KONG BC, HSUE GL, et al. Pulmonary function changes in cirrhosis of the liver[J]. Am J Gastroenterol, 1987, 82(4): 352-324.
    [12]
    YIGIT IP, HACIEVLIYAGIL SS, SECKIN Y, et al. The relationship between severity of liver cirrhosis and pulmonary function tests[J]. Dig Dis Sci, 2008, 53(7): 1951-1956. DOI: 10.1007/s10620-007-0100-2.
    [13]
    CARDOSO FS, KARVELLAS CJ. Respiratory complications before and after liver transplant[J]. J Intensive Care Med, 2019, 34(5): 355-363. DOI: 10.1177/0885066618781526.
    [14]
    FELTRACCO P, CAROLLO C, BARBIERI S, et al. Early respiratory complications after liver transplantation[J]. World J Gastroenterol, 2013, 19(48): 9271-9281. DOI: 10.3748/wjg.v19.i48.9271.
    [15]
    RAZAVI-KHORASANI N, MOAZZAMI B, DOOGHAIE MOGHADAM A, et al. Pulmonary complications in candidates for liver transplantation[J]. Middle East J Dig Dis, 2020, 12(3): 145-153. DOI: 10.34172/mejdd.2020.176.
    [16]
    AVOLIO AW, GASPARI R, TEOFILI L, et al. Postoperative respiratory failure in liver transplantation: risk factors and effect on prognosis[J]. PLoS One, 2019, 14(2): e0211678. DOI: 10.1371/journal.pone.0211678.
    [17]
    KROWKA MJ, WIESNER RH, HEIMBACH JK. Pulmonary contraindications, indications and MELD exceptions for liver transplantation: a contemporary view and look forward[J]. J Hepatol, 2013, 59(2): 367-374. DOI: 10.1016/j.jhep.2013.03.026.
    [18]
    CORDOBA J, VENTURA-COTS M, SIMÓN-TALERO M, et al. Characteristics, risk factors, and mortality of cirrhotic patients hospitalized for hepatic encephalopathy with and without acute-on-chronic liver failure (ACLF)[J]. J Hepatol, 2014, 60(2): 275-281. DOI: 10.1016/j.jhep.2013.10.004.
    [19]
    LEISE MD, POTERUCHA JJ, KAMATH PS, et al. Management of hepatic encephalopathy in the hospital[J]. Mayo Clin Proc, 2014, 89(2): 241-253. DOI: 10.1016/j.mayocp.2013.11.009.
    [20]
    RAHIMI RS, ROCKEY DC. Overuse of head computed tomography in cirrhosis with altered mental status[J]. Am J Med Sci, 2016, 351(4): 459-466. DOI: 10.1016/j.amjms.2016.02.022.
    [21]
    HANNA A, GILL I, IMAM Z, et al. Low yield of head CT in cirrhotic patients presenting with hepatic encephalopathy[J]. BMJ Open Gastroenterol, 2021, 8(1): e000609. DOI: 10.1136/bmjgast-2021-000609.
    [22]
    LIOTTA EM, ROMANOVA AL, LIZZA BD, et al. Osmotic shifts, cerebral edema, and neurologic deterioration in severe hepatic encephalopathy[J]. Crit Care Med, 2018, 46(2): 280-289. DOI: 10.1097/CCM.0000000000002831.
    [23]
    KUMAR S, MODI R, BHANDARI BM, et al. A head CT is unnecessary in the initial evaluation of a cirrhotic patient with recurrent hepatic encephalopathy[J]. Ann Hepatol, 2018, 17(5): 810-814. DOI: 10.5604/01.3001.0012.3141.
    [24]
    DA SILVA GUIMARÃES B, DE SOUZA LC, CORDEIRO HF, et al. Inspiratory muscle training with an electronic resistive loading device improves prolonged weaning outcomes in a randomized controlled trial[J]. Crit Care Med, 2021, 49(4): 589-597. DOI: 10.1097/CCM.0000000000004787.
    [25]
    BISSETT BM, LEDITSCHKE IA, NEEMAN T, et al. Inspiratory muscle training to enhance recovery from mechanical ventilation: a randomised trial[J]. Thorax, 2016, 71(9): 812-819. DOI: 10.1136/thoraxjnl-2016-208279.
    [26]
    宋德婧, 巴文天, 段军, 等. 机械通气患者咳嗽能力的评价及临床意义[J]. 中华医学杂志, 2018, 98(26): 2128-2130. DOI: 10.3760/cma.j.issn.0376-2491.2018.26.015.

    SONG DJ, BA WT, DUAN J, et al. Evaluation and clinical significance of cough ability in patients with mechanical ventilation[J]. Natl Med J China, 2018, 98(26): 2128-2130. DOI: 10.3760/cma.j.issn.0376-2491.2018.26.015.
    [27]
    JANG MH, SHIN MJ, SHIN YB. Pulmonary and physical rehabilitation in critically ill patients[J]. Acute Crit Care, 2019, 34(1): 1-13. DOI: 10.4266/acc.2019.00444.
    [28]
    LLAMAS-ÁLVAREZ AM, TENZA-LOZANO EM, LATOUR-PÉREZ J. Diaphragm and lung ultrasound to predict weaning outcome: systematic review and Meta-analysis[J]. Chest, 2017, 152(6): 1140-1150. DOI: 10.1016/j.chest.2017.08.028.
    [29]
    KIA L, CUTTICA MJ, YANG A, et al. The utility of pulmonary function testing in predicting outcomes following liver transplantation[J]. Liver Transpl, 2016, 22(6): 805-811. DOI: 10.1002/lt.24426.
    [30]
    BHANJI RA, WATT KD. Physiologic reserve assessment and application in clinical and research settings in liver transplantation[J]. Liver Transpl, 2021, 27(7): 1041-1053. DOI: 10.1002/lt.26052.
    [31]
    MAGALHÃES CBA, NOGUEIRA IC, MARINHO LS, et al. Exercise capacity impairment can predict postoperative pulmonary complications after liver transplantation[J]. Respiration, 2017, 94(3): 272-278. DOI: 10.1159/000479008.
    [32]
    VANWAGNER LB, LAPIN B, LEVITSKY J, et al. High early cardiovascular mortality after liver transplantation[J]. Liver Transpl, 2014, 20(11): 1306-1316. DOI: 10.1002/lt.23950.
    [33]
    KOSHY AN, GOW PJ, HAN HC, et al. Cardiovascular mortality following liver transplantation: predictors and temporal trends over 30 years[J]. Eur Heart J Qual Care Clin Outcomes, 2020, 6(4): 243-253. DOI: 10.1093/ehjqcco/qcaa009.
    [34]
    BARBERAN-GARCIA A, UBRÉ M, ROCA J, et al. Personalised prehabilitation in high-risk patients undergoing elective major abdominal surgery: a randomized blinded controlled trial[J]. Ann Surg, 2018, 267(1): 50-56. DOI: 10.1097/SLA.0000000000002293.
    [35]
    BRUSTIA R, SAVIER E, SCATTON O. Physical exercise in cirrhotic patients: towards prehabilitation on waiting list for liver transplantation. a systematic review and meta-analysis[J]. Clin Res Hepatol Gastroenterol, 2018, 42(3): 205-215. DOI: 10.1016/j.clinre.2017.09.005.
    [36]
    MINA DS, TANDON P, KOW AWC, et al. The role of acute in-patient rehabilitation on short-term outcomes after liver transplantation - a systematic review of the literature and expert panel recommendations. [J] Clin Transplant, 2022, DOI: 10.1111/ctr.14706[Epub ahead of print].
    [37]
    KALAITZAKIS E, ROSENGREN A, SKOMMEVIK T, et al. Coronary artery disease in patients with liver cirrhosis[J]. Dig Dis Sci, 2010, 55(2): 467-475. DOI: 10.1007/s10620-009-0738-z.
    [38]
    AN J, SHIM JH, KIM SO, et al. Prevalence and prediction of coronary artery disease in patients with liver cirrhosis: a registry-based matched case-control study[J]. Circulation, 2014, 130(16): 1353-1362. DOI: 10.1161/CIRCULATIONAHA.114.009278.
    [39]
    CHAYANUPATKUL M, LIANGPUNSAKUL S. Cirrhotic cardiomyopathy: review of pathophysiology and treatment[J]. Hepatol Int, 2014, 8(3): 308-315. DOI: 10.1007/s12072-014-9531-y.
    [40]
    IZZY M, VANWAGNER LB, LIN G, et al. Redefining cirrhotic cardiomyopathy for the modern era[J]. Hepatology, 2020, 71(1): 334-345. DOI: 10.1002/hep.30875.
    [41]
    LYSSY LA, SOOS MP. Cirrhotic cardiomyopathy[M]. Treasure Island (FL): StatPearls Publishing, 2022.
    [42]
    KHADERI S, KHAN R, SAFDAR Z, et al. Long-term follow-up of portopulmonary hypertension patients after liver transplantation[J]. Liver Transpl. 2014, 20(6): 724-727. DOI: 10.1002/lt.23870.
    [43]
    NANCHAL R, SUBRAMANIAN R, KARVELLAS CJ, et al. Guidelines for the management of adult acute and acute-on-chronic liver failure in the ICU: cardiovascular, endocrine, hematologic, pulmonary, and renal considerations[J]. Crit Care Med, 2020, 48(3): e173-e191. DOI: 10.1097/CCM.0000000000004192.
    [44]
    XU H, CHENG B, WANG R, et al. Portopulmonary hypertension: current developments and future perspectives[J]. Liver Res, 2022, 6 (1): 10-20. DOI: 10.1016/j.livres.2022.02.002.
    [45]
    GALIÈ N, HUMBERT M, VACHIERY JL, et al. 2015 ESC/ERS guidelines for the diagnosis and treatment of pulmonary hypertension: The Joint Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS): Endorsed by: Association for European Paediatric and Congenital Cardiology (AEPC), International Society for Heart and Lung Transplantation (ISHLT)[J]. Eur Heart J. 2016;37(1): 67-119. DOI: 10.1093/eurheartj/ehv317.
    [46]
    NEWSOME PN, ALLISON ME, ANDREWS PA, et al. Guidelines for liver transplantation for patients with non-alcoholic steatohepatitis[J]. Gut, 2012, 61(4): 484-500. DOI: 10.1136/gutjnl-2011-300886.
    [47]
    BERNAL W, MARTIN-MATEOS R, LIPCSEY M, et al. Aerobic capacity during cardiopulmonary exercise testing and survival with and without liver transplantation for patients with chronic liver disease[J]. Liver Transpl, 2014, 20(1): 54-62. DOI: 10.1002/lt.23766.
    [48]
    GALANT LH, FORGIARINI JUNIOR LA, DIAS AS, et al. Maximum oxygen consumption predicts mortality in patients with alcoholic cirrhosis[J]. Hepatogastroenterology, 2013, 60(125): 1127-1130. DOI: 10.5754/hge12640.
    [49]
    PRENTIS JM, MANAS DM, TRENELL MI, et al. Submaximal cardiopulmonary exercise testing predicts 90-day survival after liver transplantation[J]. Liver Transpl, 2012, 18(2): 152-159. DOI: 10.1002/lt.22426.
    [50]
    CAREY EJ, STEIDLEY DE, AQEL BA, et al. Six-minute walk distance predicts mortality in liver transplant candidates[J]. Liver Transpl, 2010, 16(12): 1373-1378. DOI: 10.1002/lt.22167.
    [51]
    TANDON P, ISMOND KP, RIESS K, et al. Exercise in cirrhosis: translating evidence and experience to practice[J]. J Hepatol, 2018, 69(5): 1164-1177. DOI: 10.1016/j.jhep.2018.06.017.
    [52]
    MERLI M, GIUSTO M, GENTILI F, et al. Nutritional status: its influence on the outcome of patients undergoing liver transplantation[J]. Liver Int, 2010, 30(2): 208-214. DOI: 10.1111/j.1478-3231.2009.02135.x.
    [53]
    MORGAN MY, MADDEN AM, SOULSBY CT, et al. Derivation and validation of a new global method for assessing nutritional status in patients with cirrhosis[J]. Hepatology, 2006, 44(4): 823-835. DOI: 10.1002/hep.21358.
    [54]
    European Association for the Study of the Liver. EASL clinical practice guidelines on nutrition in chronic liver disease[J]. J Hepatol, 2019, 70(1): 172-193. DOI: 10.1016/j.jhep.2018.06.024.
    [55]
    ENGLESBE MJ, PATEL SP, HE K, et al. Sarcopenia and mortality after liver transplantation[J]. J Am Coll Surg, 2010, 211(2): 271-278. DOI: 10.1016/j.jamcollsurg.2010.03.039.
    [56]
    KRELL RW, KAUL DR, MARTIN AR, et al. Association between sarcopenia and the risk of serious infection among adults undergoing liver transplantation[J]. Liver Transpl, 2013, 19(12): 1396-1402. DOI: 10.1002/lt.23752.
    [57]
    HEGYI PJ, SOóS A, HEGYI P, et al. Pre-transplant sarcopenic obesity worsens the survival after liver transplantation: a Meta-analysis and a systematic review[J]. Front Med (Lausanne), 2020, 7: 599434. DOI: 10.3389/fmed.2020.599434.
    [58]
    CHEN LK, WOO J, ASSANTACHAI P, et al. Asian Working Group for Sarcopenia: 2019 consensus update on sarcopenia diagnosis and treatment[J]. J Am Med Dir Assoc, 2020, 21(3): 300-307. DOI: 10.1016/j.jamda.2019.12.012.
    [59]
    HOUGH CL, LIEU BK, CALDWELL ES. Manual muscle strength testing of critically ill patients: feasibility and interobserver agreement[J]. Crit Care, 2011, 15(1): R43. DOI: 10.1186/cc10005.
    [60]
    DANG TT, EBADI M, ABRALDES JG, et al. The 6-minute walk test distance predicts mortality in cirrhosis: a cohort of 694 patients awaiting liver transplantation[J]. Liver Transpl, 2021, 27(10): 1490-1492. DOI: 10.1002/lt.26087.
    [61]
    WANG CW, COVINSKY KE, FENG S, et al. Functional impairment in older liver transplantation candidates: from the functional assessment in liver transplantation study[J]. Liver Transpl, 2015, 21(12): 1465-1470. DOI: 10.1002/lt.24334.
    [62]
    KARDASHIAN A, GE J, MCCULLOCH CE, et al. Identifying an optimal liver frailty index cutoff to predict waitlist mortality in liver transplant candidates[J]. Hepatology, 2021, 73(3): 1132-1139. DOI: 10.1002/hep.31406.
    [63]
    KLEIN CG, MALAMUTMANN E, LATUSKE J, et al. Frailty as a predictive factor for survival after liver transplantation, especially for patients with MELD≤15-a prospective study[J]. Langenbecks Arch Surg, 2021, 406(6): 1963-1969. DOI: 10.1007/s00423-021-02109-9.
    [64]
    LAI JC, SONNENDAY CJ, TAPPER EB, et al. Frailty in liver transplantation: an expert opinion statement from the American Society of Transplantation Liver and Intestinal Community of Practice[J]. Am J Transplant, 2019, 19(7): 1896-1906. DOI: 10.1111/ajt.15392.
    [65]
    TINGUELY P, MORARE N, RAMIREZ-DEL VAL A, et al. Enhanced recovery after surgery programs improve short-term outcomes after liver transplantation-a systematic review and Meta-analysis[J]. Clin Transplant, 2021, 35(11): e14453. DOI: 10.1111/ctr.14453.
    [66]
    EL FAIZY MW. Impact of early pulmonary rehabilitation on post liver transplantation[J]. J Adv Pharm Edu Res, 2019, 9(2): 7-12.
    [67]
    CELLI BR. Perioperative respiratory care of the patient undergoing upper abdominal surgery[J]. Clin Chest Med, 1993, 14(2): 253-261. doi: 10.1016/S0272-5231(21)00889-3
    [68]
    TAITO S, SHIME N, OTA K, et al. Early mobilization of mechanically ventilated patients in the intensive care unit[J]. J Intensive Care, 2016, 4: 50. DOI: 10.1186/s40560-016-0179-7.
    [69]
    DRES M, DE ABREU MG, MERDJI H, et al. Randomized clinical study of temporary transvenous phrenic nerve stimulation in difficult-to-wean patients[J]. Am J Respir Crit Care Med, 2022;205(10): 1169-1178. DOI: 10.1164/rccm.202107-1709OC.
    [70]
    LIMONGI V, DOS SANTOS DC, DE OLIVEIRA DA SILVA AM, et al. Exercise manual for liver disease patients[J]. World J Transplant, 2016, 6(2): 429-436. DOI: 10.5500/wjt.v6.i2.429.
    [71]
    ENNIS S, LOBLEY G, WORRALL S, et al. Early initiation of post-sternotomy cardiac rehabilitation exercise training (SCAR): study protocol for a randomised controlled trial and economic evaluation[J]. BMJ Open, 2018, 8(3): e019748. DOI: 10.1136/bmjopen-2017-019748.
    [72]
    SZYLIŃSKA A, LISTEWNIK M, ROTTER I, RYŁ A, et al. The efficacy of inpatient vs. home-based physiotherapy following coronary artery bypass grafting[J]. Int J Environ Res Public Health, 2018, 15(11): 2572. DOI: 10.3390/ijerph15112572.
    [73]
    KOTHARI AN, YAU RM, BLACKWELL RH, et al. Inpatient rehabilitation after liver transplantation decreases risk and severity of 30-day readmissions[J]. J Am Coll Surg, 2016, 223(1): 164-171. DOI: 10.1016/j.jamcollsurg.2016.01.061.
    [74]
    PATCAI JT, DISOTTO-MONASTERO MP, GOMEZ M, et al. Inpatient rehabilitation outcomes in solid organ transplantation: results of a unique partnership between the rehabilitation hospital and the multi-organ transplant unit in an acute hospital[J]. Open J Ther Rehabil, 2013, 1(2): 52-61. doi: 10.4236/ojtr.2013.12009
    [75]
    WALLEN MP, SKINNER TL, PAVEY TG, et al. Safety, adherence and efficacy of exercise training in solid-organ transplant candidates: a systematic review[J]. Transplant Rev (Orlando), 2016, 30(4): 218-226. DOI: 10.1016/j.trre.2016.07.004.
    [76]
    NYDAHL P, SRICHAROENCHAI T, CHANDRA S, et al. Safety of patient mobilization and rehabilitation in the intensive care unit. systematic review with Meta-analysis[J]. Ann Am Thorac Soc, 2017, 14(5): 766-777. DOI: 10.1513/AnnalsATS.201611-843SR.
    [77]
    MOYA-NÁJERA D, BORREANI S, MOYA-HERRAIZ Á, et al. Is physical exercise harmful to liver transplantation recipients? review of literature[J]. Cir Esp, 2016, 94(1): 4-10. DOI: 10.1016/j.ciresp.2015.07.002.
    [78]
    BARBERAN-GARCIA A, UBRÉ M, ROCA J, et al. Personalised prehabilitation in high-risk patients undergoing elective major abdominal surgery: a randomized blinded controlled trial[J]. Ann Surg, 2018, 267(1): 50-56. DOI: 10.1097/SLA.0000000000002293.
    [79]
    MANDELL MS, STONER TJ, BARNETT R, et al. A multicenter evaluation of safety of early extubation in liver transplant recipients[J]. Liver Transpl, 2007, 13(11): 1557-1563. DOI: 10.1002/lt.21263.
    [80]
    MAFFEI P, WIRAMUS S, BENSOUSSAN L, et al. Intensive early rehabilitation in the intensive care unit for liver transplant recipients: a randomized controlled trial[J]. Arch Phys Med Rehabil, 2017, 98(8): 1518-1525. DOI: 10.1016/j.apmr.2017.01.028.
    [81]
    TOMÁS MT, SANTA-CLARA H, BRUNO PM, et al. The impact of exercise training on liver transplanted familial amyloidotic polyneuropathy (FAP) patients[J]. Transplantation, 2013, 95(2): 372-377. DOI: 10.1097/TP.0b013e31827220e7.
    [82]
    KRASNOFF JB, VINTRO AQ, ASCHER NL, et al. A randomized trial of exercise and dietary counseling after liver transplantation[J]. Am J Transplant, 2006, 6(8): 1896-1905. DOI: 10.1111/j.1600-6143.2006.01391.x.
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