Research progress on strategies of reducing perioperative blood transfusion in liver transplantation

Zhang Li; Yang Jian; Jiang Wentao

doi:10.3969/j.issn.1674-7445.2021.01.018

Volume 12 Issue 1

Jan. 2021

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Zhang Li, Yang Jian, Jiang Wentao. Research progress on strategies of reducing perioperative blood transfusion in liver transplantation[J]. ORGAN TRANSPLANTATION, 2021, 12(1): 115-119. doi: 10.3969/j.issn.1674-7445.2021.01.018

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Research progress on strategies of reducing perioperative blood transfusion in liver transplantation

doi: 10.3969/j.issn.1674-7445.2021.01.018

Department of Liver Transplantation, Tianjin First Center Hospital, Key Laboratory of Critical Care Emergency Medicine of National Health Commission of China, Key Laboratory of Organ Transplantation in Tianjin, Key Laboratory of Transplantation Medicine of Chinese Academy of Medical Science, Tianjin 300192, China

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Corresponding author: Jiang Wentao, E-mail:jiangwentao@vip.163.com
Received Date: 2020-10-25
Available Online: 2021-01-19
Publish Date: 2021-01-19

Abstract

Abstract

Massive blood loss and blood transfusion constantly occur in liver transplantation. Over the past two decades, the amount of blood transfusion during the perioperative period has been decreased dramatically along with the continual maturity of liver transplantation techniques. The goal of liver transplantation without blood transfusion has been achieved. Since bleeding and blood transfusion are correlated with poor prognosis after liver transplantation, reducing bleeding and unnecessary blood transfusion has become the key objective during perioperative period of liver transplantation. In this article, adverse effects of allogeneic blood transfusion during perioperative period of liver transplantation, coagulation function monitoring of patients with end-stage liver disease, blood transfusion management of liver transplant recipients and the strategies of reducing perioperative blood transfusion in liver transplantation were summarized, aiming to provide reference for reducing the requirement of blood transfusion during perioperative period of liver transplantation.

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References

[1]	BISMUTH H, CASTAING D, ERICZON BG, et al. Hepatic transplantation in Europe. first report of the European Liver Transplant Registry[J]. Lancet, 1987, 2(8560):674-676. DOI: 10.1016/s0140-6736(87)92453-6.
[2]	CLEVENGER B, MALLETT SV. Transfusion and coagulation management in liver transplantation[J]. World J Gastroenterol, 2014, 20(20):6146-6158. DOI: 10.3748/wjg.v20.i20.6146.
[3]	HANNAMAN MJ, HEVESI ZG. Anesthesia care for liver transplantation[J]. Transplant Rev (Orlando), 2011, 25(1):36-43. DOI: 10.1016/j.trre.2010.10.004.
[4]	SCHUMACHER C, EISMANN H, SIEG L, et al. Preoperative recipient parameters allow early estimation of postoperative outcome and intraoperative transfusion requirements in liver transplantation[J]. Prog Transplant, 2018, 28(2):116-123. DOI: 10.1177/1526924818765805.
[5]	SHETH M, KULKARNI S, DHANIREDDY K, et al. Blood conservation strategies and liver transplantation transfusion-free techniques derived from Jehovah's Witness surgical cohorts[J]. Mo Med, 2015, 112(5):389-392.
[6]	MASSICOTTE L, THIBEAULT L, ROY A. Classical notions of coagulation revisited in relation with blood losses, transfusion rate for 700 consecutive liver transplantations[J]. Semin Thromb Hemost, 2015, 41(5):538-546. DOI: 10.1055/s-0035-1550428.
[7]	SANER FH, ABEYSUNDARA L, HARTMANN M, et al. Rational approach to transfusion in liver transplantation[J]. Minerva Anestesiol, 2018, 84(3):378-388. DOI: 10.23736/S0375-9393.17.12231-5.
[8]	DONOHUE CI, MALLETT SV. Reducing transfusion requirements in liver transplantation[J]. World J Transplant, 2015, 5(4):165-182. DOI: 10.5500/wjt.v5.i4.165.
[9]	CYWINSKI JB, ALSTER JM, MILLER C, et al. Prediction of intraoperative transfusion requirements during orthotopic liver transplantation and the influence on postoperative patient survival[J]. Anesth Analg, 2014, 118(2):428-437. DOI: 10.1213/ANE.0b013e3182a76f19.
[10]	HENDRIKS HG, VAN DER MEER J, DE WOLF JT, et al. Intraoperative blood transfusion requirement is the main determinant of early surgical re-intervention after orthotopic liver transplantation[J]. Transpl Int, 2005, 17(11):673-679. DOI: 10.1007/s00147-004-0793-5.
[11]	DAI WC, CHOK KSH, SIN SL, et al. Impact of intraoperative blood transfusion on long-term outcomes of liver transplantation for hepatocellular carcinoma[J]. ANZ J Surg, 2018, 88(5):E418-E423. DOI: 10.1111/ans.13815.
[12]	EGHBAL MH, SAMADI K, KHOSRAVI MB, et al. The impact of preoperative variables on intraoperative blood loss and transfusion requirements during orthotopic liver transplant[J]. Exp Clin Transplant, 2019, 17(4):507-512. DOI: 10.6002/ect.2016.0325.
[13]	YOELI D, ACKAH RL, SIGIREDDI RR, et al. Reoperative complications following pediatric liver transplantation[J]. J Pediatr Surg, 2018, 53(11):2240-2244. DOI: 10.1016/j.jpedsurg.2018.04.001.
[14]	BOYD SD, STENARD F, LEE DK, et al. Alloimmunization to red blood cell antigens affects clinical outcomes in liver transplant patients[J]. Liver Transpl, 2007, 13(12):1654-1661. DOI: 10.1002/lt.21241.
[15]	SANER FH, KIRCHNER C. Monitoring and treatment of coagulation disorders in end-stage liver disease[J]. Visc Med, 2016, 32(4):241-248. DOI: 10.1159/000446304.
[16]	NORTHUP P, REUTEMANN B. Management of coagulation and anticoagulation in liver transplantation candidates[J]. Liver Transpl, 2018, 24(8):1119-1132. DOI: 10.1002/lt.25198.
[17]	SOLLAZZI L, PERILLI V. End stage liver disease: a delicate balance of bleeding and thrombosis[J]. Minerva Anestesiol, 2019, 85(7):712-714. DOI: 10.23736/S0375-9393.19.13859-X.
[18]	PIETRI L, MONTALTI R, BOLONDI G, et al. Intraoperative thromboelastography as a tool to predict postoperative thrombosis during liver transplantation[J]. World J Transplant, 2020, 10(11):345-355. DOI: 10.5500/wjt.v10.i11.345.
[19]	KAMEL Y, HASSANIN A, AHMED AR, et al. Perioperative thromboelastometry for adult living donor liver transplant recipients with a tendency to hypercoagulability: a prospective observational cohort study[J]. Transfus Med Hemother, 2018, 45(6):404-412. DOI: 10.1159/000489605.
[20]	FAYED N, MOURAD W, YASSEN K, et al. Preoperative thromboelastometry as a predictor of transfusion requirements during adult living donor liver transplantation[J]. Transfus Med Hemother, 2015, 42(2): 99-108. DOI: 10.1159/000381733.
[21]	DUCHÉ M, DUCOT B, ACKERMANN O, et al. Portal hypertension in children: high-risk varices, primary prophylaxis and consequences of bleeding[J]. J Hepatol, 2017, 66(2):320-327. DOI: 10.1016/j.jhep.2016.09.006.
[22]	KOZEK-LANGENECKER SA, AHMED AB, AFSHARI A, et al. Management of severe perioperative bleeding: guidelines from the European Society of Anaesthesiology: first update 2016[J]. Eur J Anaesthesiol, 2017, 34(6):332-395. DOI: 10.1097/EJA.0000000000000630.
[23]	DETRY O, DEROOVER A, DELWAIDE J, et al. Avoiding blood products during liver transplantation[J]. Transplant Proc, 2005, 37(6):2869-2870. DOI: 10.1016/j.transproceed.2005.05.014.
[24]	AYDOGAN MS, ERDOGAN MA, YUCEL A, et al. Effects of preoperative iron deficiency on transfusion requirements in liver transplantation recipients: a prospective observational study[J]. Transplant Proc, 2013, 45(6):2277-2282. DOI: 10.1016/j.transproceed.2012.11.001.
[25]	SPAHN DR, SPAHN GH, STEIN P. Evidence base for restrictive transfusion triggers in high-risk patients[J]. Transfus Med Hemother, 2015, 42(2):110-114. DOI: 10.1159/000381509.
[26]	FORKIN KT, COLQUHOUN DA, NEMERGUT EC, et al. The coagulation profile of end-stage liver disease and considerations for intraoperative management[J]. Anesth Analg, 2018, 126(1):46-61. DOI: 10.1213/ANE. 0000000000002394.
[27]	PARK C, HUH M, STEADMAN RH, et al. Extended criteria donor and severe intraoperative glucose variability: association with reoperation for hemorrhage in liver transplantation[J]. Transplant Proc, 2010, 42(5):1738-1743. DOI: 10.1016/j.transproceed.2009.12.066.
[28]	BARBAS AS, LEVY J, MULVIHILL MS, et al. Liver transplantation without venovenous bypass: does surgical approach matter?[J]. Transplant Direct, 2018, 4(5):e348. DOI: 10.1097/TXD.0000000000000776.
[29]	PRATSCHKE S, RAUCH A, ALBERTSMEIER M, et al. Temporary intraoperative porto-caval shunts in piggy-back liver transplantation reduce intraoperative blood loss and improve postoperative transaminases and renal function: a Meta-analysis[J]. World J Surg, 2016, 40(12):2988-2998. DOI: 10.1007/s00268-016-3656-1.
[30]	DE BOER MT, MOLENAAR IQ, HENDRIKS HG, et al. Minimizing blood loss in liver transplantation: progress through research and evolution of techniques[J]. Dig Surg, 2005, 22(4):265-275. DOI: 10.1159/000088056.
[31]	SCHUMANN R, MANDELL MS, MERCALDO N, et al. Anesthesia for liver transplantation in United States academic centers: intraoperative practice[J]. J Clin Anesth, 2013, 25(7):542-550. DOI: 10.1016/j.jclinane.2013.04.017.
[32]	BREZEANU LN, BREZEANU RC, DICULESCU M, et al. Anaesthesia for liver transplantation: an update[J]. J Crit Care Med (Targu Mures), 2020, 6(2):91-100. DOI: 10.2478/jccm-2020-0011.
[33]	JAWAN B, WANG CH, CHEN CL, et al. Review of anesthesia in liver transplantation[J]. Acta Anaesthesiol Taiwan, 2014, 52(4):185-196. DOI: 10.1016/j.aat.2014.09. 004.
[34]	ADELMANN D, KRONISH K, RAMSAY MA. Anesthesia for liver transplantation[J]. Anesthesiol Clin, 2017, 35(3):491-508. DOI: 10.1016/j.anclin.2017.04.006.

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Research progress on strategies of reducing perioperative blood transfusion in liver transplantation

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