Volume 11 Issue 4
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Zhuang Jinyang, Liu Dong, Deng Gengguo, et al. Klotho: a potential protective protein for renal graft[J]. ORGAN TRANSPLANTATION, 2020, 11(4): 508-515. doi: 10.3969/j.issn.1674-7445.2020.04.015
Citation: Zhuang Jinyang, Liu Dong, Deng Gengguo, et al. Klotho: a potential protective protein for renal graft[J]. ORGAN TRANSPLANTATION, 2020, 11(4): 508-515. doi: 10.3969/j.issn.1674-7445.2020.04.015
shu

Klotho: a potential protective protein for renal graft

doi: 10.3969/j.issn.1674-7445.2020.04.015

  • Guangdong Medical University, Zhanjiang 524002, China

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  • Corresponding author: Liu Dong, Email:ld177@163.com
  • Received Date: 2020-04-24
    Available Online: 2021-01-19
  • Publish Date: 2020-07-15
    Abstract
  • Klotho gene is an anti-aging gene that is highly expressed in the kidney. Its encoding product Klotho protein can inhibit inflammation, oxidative stress injury, and apoptosis in renal tissue. It is regarded as a renal protective protein and expected to be a new target for the treatment of renal diseases. This article reviewed the biological characteristics of Klotho and the protective effect of Klotho on renal graft function.

     

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