Rare complication after pediatric living donor liver transplantation: right diaphragmatic hernia

Qu Wei; Zhu Zhijun; Wei Lin; Sun Liying; Zeng Zhigui; Liu Ying; Wang Jun; Tan Yule; Zhang Liang; He Enhui

doi:10.3969/j.issn.1674-7445.2020.04.006

Volume 11 Issue 4

Jul. 2020

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Qu Wei, Zhu Zhijun, Wei Lin, et al. Rare complication after pediatric living donor liver transplantation: right diaphragmatic hernia[J]. ORGAN TRANSPLANTATION, 2020, 11(4): 461-465. doi: 10.3969/j.issn.1674-7445.2020.04.006

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Rare complication after pediatric living donor liver transplantation: right diaphragmatic hernia

doi: 10.3969/j.issn.1674-7445.2020.04.006

1.
Department of General Surgery, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China

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Corresponding author: Zhu Zhijun, Email:zhu-zhijun@outlook.com
Received Date: 2020-04-16
Available Online: 2021-01-19
Publish Date: 2020-07-15

Abstract

Abstract

Objective To analyze the clinical characteristics, pathogenic causes and therapeutic experience of right diaphragmatic hernia after pediatric living donor liver transplantation. Methods Clinical data of 3 recipients with right diaphragmatic hernia after pediatric living donor liver transplantation were retrospectively analyzed. The clinical characteristics, diagnosis and treatment process and therapeutic experience were analyzed and summarized. Results The primary diseases of 3 children with diaphragmatic hernia after living donor liver transplantation were biliary atresia. The diaphragmatic hernia occurred at 4-6 months after liver transplantation. The contents of diaphragmatic hernia included the intraperitoneal and interperitoneal tissues and organs. Diaphragmatic defects were all located in the posterior medial area of the right diaphragm. The primary stage intermittently suturing repair was performed during intraoperative period. No diaphragmatic hernia recurred during long-term follow-up. Conclusions The clinical manifestations of right diaphragmatic hernia after pediatric living donor liver transplantation are diverse. The risk factors include malnutrition, low body weight, surgical trauma, chemical erosion caused by bile leakage, focal infection and pleural-peritoneal pressure gradient, etc. Surgical intervention is the preferred treatment strategy for diaphragmatic hernia after liver transplantation.
- Pediatric liver transplantation,
- Living donor liver transplantation,
- Diaphragmatic hernia,
- Biliary atresia,
- Alkaline phosphatase,
- Portal hypertension,
- Bile leakage

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Rare complication after pediatric living donor liver transplantation: right diaphragmatic hernia

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