Research progress on carbapenem-resistant <i>Klebsiella pneumoniae</i> infection in organ transplantation

Liu Weiwang; Wang Xiao; Li Chuanchang

doi:10.3969/j.issn.1674-7445.2020.03.015

Volume 11 Issue 3

May 2020

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Liu Weiwang, Wang Xiao, Li Chuanchang. Research progress on carbapenem-resistant Klebsiella pneumoniae infection in organ transplantation[J]. ORGAN TRANSPLANTATION, 2020, 11(3): 405-412. doi: 10.3969/j.issn.1674-7445.2020.03.015

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Liu Weiwang, Wang Xiao, Li Chuanchang. Research progress on carbapenem-resistant Klebsiella pneumoniae infection in organ transplantation[J]. ORGAN TRANSPLANTATION, 2020, 11(3): 405-412. doi: 10.3969/j.issn.1674-7445.2020.03.015

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Research progress on carbapenem-resistant Klebsiella pneumoniae infection in organ transplantation

doi: 10.3969/j.issn.1674-7445.2020.03.015

Department of Geriatrics, Xiangya Hospital of Central South University, Changsha 410008, China

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Corresponding author: Li Chuanchang E-mail:lichuanchang@csu.edu.cn
Received Date: 2020-02-22
Available Online: 2021-01-19
Publish Date: 2020-05-15

Abstract

Abstract

Klebsiella pneumoniae (KP) is a common conditional pathogen, and also one of the common pathogens causing infection in immunocompromised patients, with its infection rate increasing year by year. Carbapenem antibiotics are effective drugs to control KP infection. But with the widespread use of carbapenem antibiotics, carbapenemresistant Klebsiella pneumoniae (CRKP) appears and increases year by year. Organ transplant recipients are at high risk of CRKP infection due to the suppressed immune system. Once drug-resistant bacteria infection occurs, it is often difficult to control and the survival rate of transplant organs is reduced, which brings great challenges to clinical treatment. In this article, the current status and treatment progress of CRKP infection in organ transplantation are summarized.
- Organ transplantation,
- Carbapenem-resistant Klebsiella pneumoniae,
- Infection,
- Donation after cardiac death,
- Delayed graft function,
- Intensive care unit,
- Ceftazidime-avibactam,
- Phage

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References

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Research progress on carbapenem-resistant Klebsiella pneumoniae infection in organ transplantation

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