Research progress on biomarkers of rejection risk in organ transplantation

Shi Bingyi; Chen Wen; Liu Zhijia

doi:10.3969/j.issn.1674-7445.2020.02.003

Volume 11 Issue 2

Mar. 2020

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Shi Bingyi, Chen Wen, Liu Zhijia. Research progress on biomarkers of rejection risk in organ transplantation[J]. ORGAN TRANSPLANTATION, 2020, 11(2): 194-198. doi: 10.3969/j.issn.1674-7445.2020.02.003

Citation:

Shi Bingyi, Chen Wen, Liu Zhijia. Research progress on biomarkers of rejection risk in organ transplantation[J]. ORGAN TRANSPLANTATION, 2020, 11(2): 194-198. doi: 10.3969/j.issn.1674-7445.2020.02.003

Citation:

Shi Bingyi, Chen Wen, Liu Zhijia. Research progress on biomarkers of rejection risk in organ transplantation[J]. ORGAN TRANSPLANTATION, 2020, 11(2): 194-198. doi: 10.3969/j.issn.1674-7445.2020.02.003

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Research progress on biomarkers of rejection risk in organ transplantation

doi: 10.3969/j.issn.1674-7445.2020.02.003

Organ Transplantation Institute of the 8th Medical Center of Chinese PLA General Hospital, Beijing 100091, China

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Corresponding author: Shi Bingyi, Email: shibingyi666@126.com
Received Date: 2020-02-04
Available Online: 2021-01-19
Publish Date: 2020-03-15

Abstract

Abstract

Rejection is the main cause of transplantation failure. Currently, the specificity and sensitivity of clinical parameters are relatively poor, which cannot accurately prompt the exact cause of rejection. It is of great clinical significance to explore novel biomarkers for monitoring the rejection. In this article, the latest research progress on the biomarkers of rejection risk in organ transplantation were summarized from the perspectives of transplantation pathology, immune cells and regulatory immune cells, non-human leukocyte antigen antibodies, exosomes, cell-free DNA and combination gene prediction, aiming to provide reference for early warning and treatment of rejection in organ transplantation.
- Organ transplantation,
- Transplantation immunity,
- Rejection,
- Transplantation pathology,
- Immune cell,
- Non-human leukocyte antigen antibody,
- Exosomes,
- Cell-free DNA(cfDNA),
- Combination gene prediction

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References(24)

References

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Research progress on biomarkers of rejection risk in organ transplantation

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