Effect of the ratio of living related donor renal volume to recipient body surface area on early function of transplanted kidney

  Objective   To investigate the relationship between the ratio of living related donor renal volume (RV) to recipient body surface area (BSA) (RV/BSA) and early postoperative function of transplanted kidney.

  Methods   Clinical data of 120 pairs of donors and recipients undergoing living related renal transplantation were retrospectively analyzed. According to the RV/BSA ratio, the recipients were divided into group A (RV/BSA < 65.33 mL/m²), group B (RV/BSA 65.33~76.49 mL/m²), group C (RV/BSA 76.50~96.96 mL/m²) and group D (RV/BSA > 96.96 mL/m²). The postoperative estimated glomerular filtration rate (eGFR) of recipients was compared among 4 groups. The correlation between the RV/BSA and eGFR of recipients at postoperative 6 and 12 months was analyzed.

  Results   The eGFR at postoperative 6 month in group A was significantly lower than that in groups B, C and D (t=2.313, 2.947, 5.903; all P < 0.05). The eGFR at postoperative 12 month in group A was also significantly lower than that in groups B, C and D (t=2.189, 2.433, 2.909; all P < 0.05). The RV/BSA was significantly correlated with the eGFR of recipients at postoperative 6 and 12 months (all P < 0.05).

  Conclusions  RV/BSA is intimately correlated with the early function of transplanted kidney after living related renal transplantation.