Volume 7 Issue 3
May  2016
Turn off MathJax
Article Contents
Article Navigation >  ORGAN TRANSPLANTATION  > 2016  >  7(3): 215-218
Fu Binsheng, Yi Shuhong, Tang Hui, et al. Experience of quality evaluation and function maintenance of donor liver from organ donation after citizen's death[J]. ORGAN TRANSPLANTATION, 2016, 7(3): 215-218. doi: 10.3969/j.issn.1674-7445.2016.03.011
Citation: Fu Binsheng, Yi Shuhong, Tang Hui, et al. Experience of quality evaluation and function maintenance of donor liver from organ donation after citizen's death[J]. ORGAN TRANSPLANTATION, 2016, 7(3): 215-218. doi: 10.3969/j.issn.1674-7445.2016.03.011
shu

Experience of quality evaluation and function maintenance of donor liver from organ donation after citizen's death

doi: 10.3969/j.issn.1674-7445.2016.03.011

  • Department of Hepatic Surgery, Organ Transplantation Center, the Third Affiliated Hospital of Sun Yat-sen University, Organ Transplantation Research Center of Guangdong Province, Transplantation Research Institute of Sun Yat-sen University, Guangzhou 510630, China

More Information
  • Corresponding author: Chen Guihua, Email:chgh1955@263.net
  • Received Date: 2016-03-02
    Available Online: 2021-01-19
  • Publish Date: 2016-05-15
    Abstract
  •   Objective  To summarize the experience of quality evaluation and function maintenance of donor liver from organ donation after citizen's death.  Methods  Clinical data of 93 donors and 87 patients undergoing liver transplantation in the Third Affiliated Hospital of Sun Yat-sen University form July 2012 to June 2015 were retrospectively analyzed. The experience of quality evaluation and function maintenance of donor liver was briefly introduced. The procurement and utilization of donor organs and the recovery of recipients undergoing donor liver transplantation were summarized.  Results  The mean warm ischemia time of donor organ was 8 min (1-12 min). The organ procurement surgery was successfully performed with an average duration of 32 min (20-52 min). In total, 93 donor livers were obtained, 87 utilized for liver transplantation and 6 discarded (3 cases of severe fatty liver disease, 2 of hepatic fibrosis and 1 of hepatic tearing injury). Two patients underwent combined liver and kidney transplantation. The function of liver graft recovered well. Merely 1 case presented with primary liver graft non-function.  Conclusions  Early and accurate evaluation and maintenance of donor livers from organ donation after citizen's death can enhance the quality of organ graft and improve the transplantation efficacy.

     

    • FullText(HTML)
  • loading
    • References(17)
  • [1]
    Watts RP, Thom O, Fraser JF. Inflammatory signalling associated with brain dead organ donation: from brain injury to brain stem death and posttransplant ischaemia reperfusion injury[J]. J Transplant, 2013:521369. http://cn.bing.com/academic/profile?id=1977853109&encoded=0&v=paper_preview&mkt=zh-cn
    [2]
    Mathur AK, Heimbach J, Steffick DE, et al. Donation after cardiac death liver transplantation: predictors of outcome[J]. Am J Transplant, 2010, 10(11):2512-2519. doi: 10.1111/ajt.2010.10.issue-11
    [3]
    蓝柳根, 秦科, 董建辉, 等.公民逝世后器官捐献供肝移植31例临床效果分析[J].器官移植, 2015, 6(5):316-321. http://www.organtranspl.com/CN/article/downloadArticleFile.do?attachType=PDF&id=8849

    Lan LG, Qin K, Dong JH, et al. Clinical effect analysis of liver transplantation from donation after citizen's death in 31 cases[J]. Organ Transplant, 2015, 6(5):316-321. http://www.organtranspl.com/CN/article/downloadArticleFile.do?attachType=PDF&id=8849
    [4]
    邓斐文, 陈焕伟, 甄作均, 等.高MELD评分终末期肝病患者接受中国公民逝世后器官捐献供肝肝移植的近期疗效评价[J].器官移植, 2015, 6(2):86-92. http://www.organtranspl.com/Public/Uploads/Wall/2016-01-11/20160111074831.pdf

    Deng FW, Chen HW, Zhen ZJ, et al. Short-term clinical efficacy of liver transplantation with organs from donation after Chinese citizens' death in patients with high model for end-stage liver disease score[J]. Organ Transplant, 2015, 6(2):86-92. http://www.organtranspl.com/Public/Uploads/Wall/2016-01-11/20160111074831.pdf
    [5]
    傅斌生, 易慧敏, 易述红, 等.公民逝世后器官捐献肝移植单中心临床疗效分析及初步经验[J/CD].中华肝脏外科手术学电子杂志, 2015, 4(2):88-91. http://www.docin.com/p-1243408187.html

    Fu BS, Yi HM, Yi SH, et al. Single-center analysis on curative effect of liver transplantation from organ donation by citizens after death and initial experience[J/CD]. Chin J Hepatic Surg (Electr Edit), 2015, 4(2):88-91. http://www.docin.com/p-1243408187.html
    [6]
    Ledinh H, Meurisse N, Delbouille MH, et al. Contribution of donors after cardiac death to the deceased donor pool: 2002 to 2009 University of Liege experience[J]. Transplant Proc, 2010, 42(10):4369-4372. doi: 10.1016/j.transproceed.2010.07.018
    [7]
    Elias-Miro M, Massip-Salcedo M, Jimenez-Castro M, et al. Does adiponectin benefit steatotic liver transplantation?[J]. Liver Transpl, 2011, 17(9):993-1004. http://cn.bing.com/academic/profile?id=2035414701&encoded=0&v=paper_preview&mkt=zh-cn
    [8]
    Perera MT, Bramhall SR. Current status and recent advances of liver transplantation from donation after cardiac death[J]. World J Gastrointest Surg, 2011, 3(11):167-176. doi: 10.4240/wjgs.v3.i11.167
    [9]
    Lee KW, Simpkins CE, Montgomery RA, et al. Factors affecting graft survival after liver transplantation from donation after cardiac death donors[J]. Transplantation, 2006, 82(12):1683-1688. doi: 10.1097/01.tp.0000250936.73034.98
    [10]
    O'Neill S, Roebuck A, Khoo E, et al. A meta-analysis and meta-regression of outcomes including biliary complications in donation after cardiac death liver transplantation[J]. Transpl Int, 2014, 27(11):1159-1174. doi: 10.1111/tri.2014.27.issue-11
    [11]
    Nguyen JH, Bonatti H, Dickson RC, et al. Long-term outcomes of donation after cardiac death liver allografts from a single center[J]. Clin Transplant, 2009, 23(2):168-173. doi: 10.1111/ctr.2009.23.issue-2
    [12]
    Frongillo F, Lirosi MC, Sganga G, et al. Graft steatosis as a risk factor of ischemic-type biliary lesions in liver transplantation[J]. Transplant Proc, 2014, 46(7):2293-2294. doi: 10.1016/j.transproceed.2014.07.057
    [13]
    Karpeta E, Czerwiński J, Wasiak D, et al. Risk factors in cadaveric donors of livers procured for elective and urgent recipients[J]. Transplant Proc, 2012, 44(7):2250-2252. doi: 10.1016/j.transproceed.2012.07.115
    [14]
    Goldaracena N, Quiñonez E, Méndez P, et al. Extremely marginal liver grafts from deceased donors have outcome similar to ideal grafts[J]. Transplant Proc, 2012, 44(7):2219-2222. doi: 10.1016/j.transproceed.2012.07.113
    [15]
    Loggi E, Micco L, Ercolani G, et al. Liver transplantation from hepatitis B surface antigen positive donors: a safe way to expand the donor pool[J]. J Hepatol, 2012, 56(3):579-585. doi: 10.1016/j.jhep.2011.09.016
    [16]
    Monbaliu D, Pirenne J, Talbot D. Liver transplantation using donation after cardiac death donors[J]. J Hepatol, 2012, 56(2):474-485. doi: 10.1016/j.jhep.2011.07.004
    [17]
    Le Dinh H, de Roover A, Kaba A, et al. Donation after cardio-circulatory death liver transplantation[J]. World J Gastroenterol, 2012, 18(33):4491-4506. doi: 10.3748/wjg.v18.i33.4491
    • Relative Articles
    • Supplements(0)
    • Cited By
  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索
    Get Citation
    PDF
    XML

    Article Metrics

    Article views (179) PDF downloads(9) Cited by()
    Proportional views
    Related

    WeChat Subscription Account

    Wechat Service Account

    Contact Us
    • Tel：020-38736410
    • Email: organtranspl@163.com
    • Address：The Third Affiliated Hospital of Sun Yat-sen University, No. 600, Tianhe Road, Tianhe District, Guangzhou
    • Editorial Office of Organ Transplantation  粤ICP备2021030844号
    Links

    Supported by: Beijing Renhe Information Technology Co. Ltd    

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return