Retinoid X receptor signaling pathway in leukemia

Lu Xiaoxi; Ma Zhigui; Gao Ju; Zhu Yiping

doi:10.3969/j.issn.1674-7445.2014.06.013

Volume 5 Issue 6

Nov. 2014

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Lu Xiaoxi, Ma Zhigui, Gao Ju, et al. Retinoid X receptor signaling pathway in leukemia[J]. ORGAN TRANSPLANTATION, 2014, 5(6): 383-388. doi: 10.3969/j.issn.1674-7445.2014.06.013

Citation:

Lu Xiaoxi, Ma Zhigui, Gao Ju, et al. Retinoid X receptor signaling pathway in leukemia[J]. ORGAN TRANSPLANTATION, 2014, 5(6): 383-388. doi: 10.3969/j.issn.1674-7445.2014.06.013

Citation:

Lu Xiaoxi, Ma Zhigui, Gao Ju, et al. Retinoid X receptor signaling pathway in leukemia[J]. ORGAN TRANSPLANTATION, 2014, 5(6): 383-388. doi: 10.3969/j.issn.1674-7445.2014.06.013

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Retinoid X receptor signaling pathway in leukemia

doi: 10.3969/j.issn.1674-7445.2014.06.013

Department of Pediatric Hematology and Oncology, West China Second University Hospital of Sichuan University, Chengdu 610041, China

Funds:

National Natural Science Foundation 81000215

The technology bureau of Chengdu 11DXYB086JH-027

More Information

Corresponding author: Zhu Yiping, Email: yipingzhu918@qq.com
Received Date: 2014-07-20
Available Online: 2021-01-19
Publish Date: 2014-11-15

Abstract

Abstract

Retinoid X receptor (RXR) acts as ligand-dependent transcription factors playing an important role in regulating a serial of physiological processes, such as embryo development and organ homeostasis. At the molecular level, RXRs exert their functions by inter-activating with multiple signal pathways to regulate target gene expression which control cell growth, differentiation, survival and death. The interference in the network of RXR and other signal pathways has turned RXR into an attractive drug target.
- Retinoid X receptor,
- Signal pathway,
- Leukemia,
- Bone marrow transplantation

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References(38)

References

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Retinoid X receptor signaling pathway in leukemia

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