Pancreatic islet cells derived from pluripotent stem cells and their application in the treatment of diabetes
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摘要: 干细胞体外定向分化技术的发展使体外再造可用于移植的胰岛细胞或组织成为可能,同时基于包囊等技术的辅助免疫调控方式为解决移植后的免疫排斥反应提供了方案,这些新技术的高速发展为糖尿病的细胞治疗奠定了基础。本文着重探讨人类胰腺发育过程与干细胞定向分化的关系、干细胞体外胰向分化系统的建立以及免疫调控技术在多能干细胞(PSC)胰岛移植中的应用。
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