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肾移植组织配型及免疫监测技术操作规范(2019版)

中华医学会器官移植学分会

中华医学会器官移植学分会. 肾移植组织配型及免疫监测技术操作规范(2019版)[J]. 器官移植, 2019, 10(5): 513-520. doi: 10.3969/j.issn.1674-7445.2019.05.009
引用本文: 中华医学会器官移植学分会. 肾移植组织配型及免疫监测技术操作规范(2019版)[J]. 器官移植, 2019, 10(5): 513-520. doi: 10.3969/j.issn.1674-7445.2019.05.009
Branch of Organ Transplantation of Chinese Medical Association. Technical operation specification for tissue matching and immune monitoring techniques in renal transplantation (2019 edition)[J]. ORGAN TRANSPLANTATION, 2019, 10(5): 513-520. doi: 10.3969/j.issn.1674-7445.2019.05.009
Citation: Branch of Organ Transplantation of Chinese Medical Association. Technical operation specification for tissue matching and immune monitoring techniques in renal transplantation (2019 edition)[J]. ORGAN TRANSPLANTATION, 2019, 10(5): 513-520. doi: 10.3969/j.issn.1674-7445.2019.05.009

肾移植组织配型及免疫监测技术操作规范(2019版)

doi: 10.3969/j.issn.1674-7445.2019.05.009
基金项目: 

国家自然科学基金 81570680

国家自然科学基金 81571555

详细信息
    通讯作者:

    肖漓, 女, 1972年生, 博士, 主任技师, 研究方向为移植免疫学, Email:xiaolilab309@163.com

  • 中图分类号: R617, R392.4

Technical operation specification for tissue matching and immune monitoring techniques in renal transplantation (2019 edition)

  • 摘要: 为了进一步规范肾移植组织配型及免疫监测技术操作, 中华医学会器官移植学分会组织器官移植学专家从组织配型基本技术、配型方法、群体反应性抗体、供体特异性抗体、受者免疫监测等方面, 制订本规范。

     

  • 表  1  HLA Ⅰ类抗原氨基酸残基配型标准

    Table  1.   The matching standard type of amino acid residues of HLA Ⅰ antigen

    Res M分组 抗原特异性
    A1(R114) A1, A3, A11, A29, A36
    A2(K127) A2, A23, A24, A68, A69
    A10/A19(Q114) A25, A26, A34, A66, A19(A31, A32, A33, A74), A43
    B5/B8(F67) B5(B51), B35, B53, B78, B8, B57
    B7(A71-D74) B7, B22(B54, B55, B56), B27, B42, B46, B67
    B8(T69-S77) B8, B14(B64, B65), B16(B39), B78
    B12(T41) B12(B44, B45), B13, B21(B49, B50), B40(B60, B61), B41, B47
    B17/B63(S70) B17(B57, 58), B63, B59
    Bw4(R83) A9(A23, A24), A25, A32, B5(B51, B52), B12, B13, B17(B57, B58), B21(B49), B27, B37, B38, B47, B53, B59, B63, B77
    Bw6(N80) A11, B7, B8, B18, B14(B64, B65), B15(B62, B75, B76, B78), B16(B39), B22(B54, B55, B56), B35, B40(B60, B61, B48, B4005), B41, B42, B45, B46, B50, B67, B70, B71, B72
    下载: 导出CSV

    表  2  HLA Ⅱ类抗原氨基酸残基配型标准

    Table  2.   The matching standard type of amino acid residues of HLA Ⅱ antigen

    Res M分组 抗原特异性
    DQ1 DR1(DR10), DR2(DR15, DR16), DR6(DR13, DR14)
    DQ2 DR3(DR17, DR18), DR7
    DQ3 DR4, DR5(DR11, DR12), DR9, DR14
    DQ4 DR8, DR18
    DRB3 DR3(DR17, DR18), DR5(DR11, DR12)DR6(DR13, DR14)
    DRB4 DR4, DR7, DR9
    DRB5 DR1(DR10), DR2(DR15, DR16)
    下载: 导出CSV
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出版历程
  • 收稿日期:  2019-06-16
  • 网络出版日期:  2021-01-19
  • 刊出日期:  2019-09-15

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