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肾移植术后局灶节段性肾小球硬化复发的研究进展

刘莉莉 孙启全

刘莉莉, 孙启全. 肾移植术后局灶节段性肾小球硬化复发的研究进展[J]. 器官移植, 2018, 9(4): 322-324. doi: 10.3969/j.issn.1674-7445.2018.04.015
引用本文: 刘莉莉, 孙启全. 肾移植术后局灶节段性肾小球硬化复发的研究进展[J]. 器官移植, 2018, 9(4): 322-324. doi: 10.3969/j.issn.1674-7445.2018.04.015

肾移植术后局灶节段性肾小球硬化复发的研究进展

doi: 10.3969/j.issn.1674-7445.2018.04.015
基金项目: 

国家自然科学青年基金 81200523

首都临床特色应用研究项目 Z151100004015083

国家科技重大新药创制专项 2017ZX09304026

北京医院121工程项目 121-2016008

详细信息
    作者简介:

    刘莉莉,女,1981年生,博士,研究方向为肾小球疾病,Email:lll_9536@163.com

    通讯作者:

    孙启全,男,1973年生,博士,主任医师,研究方向为肾移植相关疾病,Email:sunqiq@mail.sysu.edu

  • 中图分类号: R617

  • 摘要: 局灶节段性肾小球硬化(FSGS)患者肾移植术后容易复发,是导致移植肾失功的重要原因之一。从循环因子学说到近年对足细胞靶抗原的认识,移植后FSGS复发的机制研究越来越深入,而针对足细胞抗原的靶向治疗也显示出广泛的应用前景。本文就肾移植术后FSGS的临床分型及危险因素、FSGS复发的机制、FSGS复发的预防和治疗进行综述。

     

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出版历程
  • 收稿日期:  2018-05-16
  • 网络出版日期:  2021-01-19
  • 刊出日期:  2018-07-15

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