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摘要: 局灶节段性肾小球硬化(FSGS)患者肾移植术后容易复发,是导致移植肾失功的重要原因之一。从循环因子学说到近年对足细胞靶抗原的认识,移植后FSGS复发的机制研究越来越深入,而针对足细胞抗原的靶向治疗也显示出广泛的应用前景。本文就肾移植术后FSGS的临床分型及危险因素、FSGS复发的机制、FSGS复发的预防和治疗进行综述。
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