Toll样受体2在器官移植中的研究进展

陈继承; 蔡志明; 牟丽莎

doi:10.3969/j.issn.1674-7445.2018.03.015

Toll样受体2在器官移植中的研究进展

doi: 10.3969/j.issn.1674-7445.2018.03.015

510275 广东深圳，深圳市第二人民医院

基金项目:

国家重点研发计划 2017YFC1103704

深圳市科创委学科布局项目 JCYJ20170306092047810

深圳市高水平医学学科建设专项基金 2016031638

深圳市医疗卫生三名工程 SZSM201412020

深圳市科技计划 JCJY20160229204849975

深圳市科技计划 GJHZ20170314171357556

深圳市卫生计生系统科研项目 SZXJ2017021

中国博士后科学基金面上项目 2016M602584

详细信息

作者简介:
陈继承，男，1986年生，博士后，研究方向为免疫学，Email：751761270@qq.com

通讯作者:
牟丽莎，女，1983年生，博士，副研究员，研究方向为异种胰岛移植，Email：molly_molly@163.com

中图分类号: R617
计量
- 文章访问数: 148
- HTML全文浏览量: 98
- PDF下载量: 7
- 被引次数: 0
出版历程
- 收稿日期: 2018-02-15
- 网络出版日期: 2021-01-19
- 刊出日期: 2018-05-15

摘要

摘要: Toll样受体（TLR）2在先天性免疫和适应性免疫中都起着重要作用，近年来，越来越多的文献报道TLR2与移植排斥反应密切相关，针对TLR2信号系统的相关免疫抑制靶点研发的免疫抑制剂可能会减轻器官移植术后的排斥反应。本文综述了TLR2在缺血-再灌注损伤、同种器官移植以及异种器官移植中的近期研究进展。
- 器官移植 /
- Toll样受体2 /
- 免疫排斥反应 /
- 免疫抑制剂 /
- 异种器官移植 /
- 缺血-再灌注损伤 /
- 同种器官移植

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参考文献(25)

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