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公民逝世后器官捐献供肝肝移植单中心经验总结

邓斐文 陈焕伟 甄作均

邓斐文, 陈焕伟, 甄作均. 公民逝世后器官捐献供肝肝移植单中心经验总结[J]. 器官移植, 2017, 8(6): 435-439. doi: 10.3969/j.issn.1674-7445.2017.06.005
引用本文: 邓斐文, 陈焕伟, 甄作均. 公民逝世后器官捐献供肝肝移植单中心经验总结[J]. 器官移植, 2017, 8(6): 435-439. doi: 10.3969/j.issn.1674-7445.2017.06.005
Deng Feiwen, Chen Huanwei, Zhen Zuojun. Liver transplantation from donor liver of organ donation after citizen's death: a single center experience[J]. ORGAN TRANSPLANTATION, 2017, 8(6): 435-439. doi: 10.3969/j.issn.1674-7445.2017.06.005
Citation: Deng Feiwen, Chen Huanwei, Zhen Zuojun. Liver transplantation from donor liver of organ donation after citizen's death: a single center experience[J]. ORGAN TRANSPLANTATION, 2017, 8(6): 435-439. doi: 10.3969/j.issn.1674-7445.2017.06.005

公民逝世后器官捐献供肝肝移植单中心经验总结

doi: 10.3969/j.issn.1674-7445.2017.06.005
基金项目: 

广东省医学科研基金 A2014697

佛山市医学类科技攻关项目 2014AB00263

佛山市卫生局医学科研基金 2014029

详细信息
    通讯作者:

    陈焕伟, Email: chwei_fsyyy@163.com

  • 中图分类号: R617

Liver transplantation from donor liver of organ donation after citizen's death: a single center experience

More Information
  • 摘要:   目的  探讨公民逝世后器官捐献(器官捐献)供肝在临床肝移植中的应用效果。  方法  回顾性分析2011年10月至2016年12月在佛山市第一人民医院进行75例器官捐献肝移植的供、受者临床资料,对供者情况进行严格评估。总结肝移植受者的预后情况和并发症发生情况。  结果  75例肝移植受者1年累积存活率为88%,3年累积存活率为78%。9例受者死亡原因分别为移植术后肝癌复发转移4例、移植物抗宿主病1例、重症肺部感染1例、乙型病毒性肝炎(乙肝)复发肝衰竭1例、术后多器官功能衰竭1例、上消化道大出血1例。13例肝移植受体发生胆道狭窄,其中1例自行缓解,1例行经皮经肝胆管引流术(PTBD)治愈,11例行内镜下逆行性胰胆管造影术(ERCP)胆道内支架置入治疗,5例治愈,2例转行胆肠吻合术治疗治愈,4例仍在临床观察中。  结论  器官捐献供肝应用在临床肝移植中可取得良好的效果。对供体进行严格评估、受者围手术期规范管理、使用无肾上腺皮质激素免疫抑制维持方案、及时有效地处理并发症、术后定期随访是保证器官捐献供肝肝移植成功和受者长期生存的重要措施。

     

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出版历程
  • 收稿日期:  2017-08-17
  • 网络出版日期:  2021-01-19
  • 刊出日期:  2017-11-15

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