婴幼儿公民逝世后器官捐献成人双肾移植的临床效果(附2例报告)

丁汉东; 廖贵益; 钟金彪; 赵飞

doi:10.3969/j.issn.1674-7445.2017.04.008

婴幼儿公民逝世后器官捐献成人双肾移植的临床效果(附2例报告)

doi: 10.3969/j.issn.1674-7445.2017.04.008

230022 合肥, 安徽医科大学第一附属医院泌尿外科

基金项目:

安徽省自然科学基金 1508085SMH226

详细信息

通讯作者:
廖贵益, Email: liaoguiyi2@sina.com

中图分类号: R617
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- 被引次数: 0
出版历程
- 收稿日期: 2017-04-15
- 网络出版日期: 2021-01-19
- 刊出日期: 2017-07-15

Clinical efficacy of en-bloc kidney transplantation from infantile donor organs to adult recipients: report of two cases

Department of Urology, the First Affiliated Hospital of Anhui Medical University, Hefei 230022, China

More Information

Corresponding author: Liao Guiyi, Email: liaoguiyi2@sina.com

摘要

摘要: 目的探讨婴幼儿公民逝世后器官捐献成人肾移植的临床效果。方法回顾性分析2例婴幼儿供肾成人肾移植的临床资料、手术方式、免疫抑制剂应用和随访情况并复习相关文献。结果 1例男性受者原发病为慢性肾脏病变、肾衰竭, 术后移植肾功能恢复良好, 移植肾体积逐渐增大, 末次随访时（术后10个月）血清肌酐为84 μmol/L。另1例女性受者原发病为肾衰竭尿毒症期, 术后23 d死于心力衰竭合并严重肺部感染。2例受者均未发生血管并发症。结论婴幼儿捐献成人肾移植术后早期临床效果良好, 移植肾增长迅速。术中精细操作, 有利于预防供肾动脉血栓栓塞等并发症的发生。
- 肾移植 /
- 婴幼儿 /
- 公民逝世后器官捐献 /
- 存活率 /
- 双肾整体移植 /
- 代偿性增生 /
- 代偿率 /
- 血管吻合
Abstract: Objective To evaluate the clinical efficacy of en-bloc kidney transplantation from infantile organ donation after citizen's death to adult recipients. Methods Clinical data, surgical approach, use of immunosuppressive agents and follow-up of two adults undergoing kidney transplantation from infantile donor organs were retrospectively analyzed. Relevant literature review was performed. Results One male recipient was diagnosed with primary diseases of chronic renal lesions and renal failure. After kidney transplantation, the recipient obtained favorable recovery of kidney function. The grafted kidney was gradually increased in size. During the final follow-up (10 months after surgery), the serum creatinine level was measured as 84 μmol/L. The other female recipient was diagnosed with renal failure accompanied with uremia. The recipient died from heart failure complicated with severe pulmonary infection at postoperative 23 d. No vascular complications occurred in either recipient. Conclusions Kidney transplantation from infantile donor organs to adult recipients yields favorable clinical efficacy and the grafted kidney is significantly increased in size during the early stage. Precise intraoperative manipulation contributes to preventing the incidence of arterial embolism of the donor kidney and other postoperative complications.
- Kidney transplantation /
- Infant /
- Organ donation after citizen's death /
- Survival rate /
- En-bloc kidney transplantation /
- Compensatory hyperplasia /
- Compensation rate /
- Vascular anastomosis

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参考文献(18)

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