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索非布韦联合利巴韦林治疗肝移植术后丙型病毒性肝炎复发:附1例报告

张静 张胥丰 刘学民 刘正稳 吕毅

张静, 张胥丰, 刘学民, 等. 索非布韦联合利巴韦林治疗肝移植术后丙型病毒性肝炎复发:附1例报告[J]. 器官移植, 2016, 7(1): 61-63. doi: 10.3969/j.issn.1674-7445.2016.01.012
引用本文: 张静, 张胥丰, 刘学民, 等. 索非布韦联合利巴韦林治疗肝移植术后丙型病毒性肝炎复发:附1例报告[J]. 器官移植, 2016, 7(1): 61-63. doi: 10.3969/j.issn.1674-7445.2016.01.012

索非布韦联合利巴韦林治疗肝移植术后丙型病毒性肝炎复发:附1例报告

doi: 10.3969/j.issn.1674-7445.2016.01.012
基金项目: 

国家自然科学基金 81470896

详细信息
    通讯作者:

    吕毅, Email:luyi169@126.com

  • 中图分类号: R617;R512.6+3

  • 摘要: 报道1例通过自行服用索非布韦+利巴韦林成功治疗肝移植术后丙型病毒性肝炎(丙肝)复发的个案, 为肝移植术后丙肝复发的治疗提供参考, 以延长移植肝的存活时间, 改善患者的预后。索非布韦+利巴韦林方案能快速有效地降低肝移植术后血清丙型肝炎病毒(HCV)RNA定量, 消除病毒对移植肝损伤, 因此可作为肝移植术后丙肝复发的有效治疗手段, 但仍需密切观察白细胞减低等不良反应的发生情况。

     

  • 图  1  本例患者HCV RNA定量的变化

    Figure  1.  Change of HCV RNA quantification of the patient

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出版历程
  • 收稿日期:  2015-10-11
  • 网络出版日期:  2021-01-19
  • 刊出日期:  2016-01-15

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