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活体肾移植供肾肾小球滤过率对术后移植肾功能恢复的影响

苏子庭 李珍 曾仲 刘涛 段键 黄汉飞 林杰

苏子庭, 李珍, 曾仲, 等. 活体肾移植供肾肾小球滤过率对术后移植肾功能恢复的影响[J]. 器官移植, 2015, 6(5): 331-334, 339. doi: 10.3969/j.issn.1674-7445.2015.05.011
引用本文: 苏子庭, 李珍, 曾仲, 等. 活体肾移植供肾肾小球滤过率对术后移植肾功能恢复的影响[J]. 器官移植, 2015, 6(5): 331-334, 339. doi: 10.3969/j.issn.1674-7445.2015.05.011
Su Ziting, Li Zhen, Zeng Zhong, et al. Influence of glomerular filtration rate of living donor on recovery of graft function after transplantation[J]. ORGAN TRANSPLANTATION, 2015, 6(5): 331-334, 339. doi: 10.3969/j.issn.1674-7445.2015.05.011
Citation: Su Ziting, Li Zhen, Zeng Zhong, et al. Influence of glomerular filtration rate of living donor on recovery of graft function after transplantation[J]. ORGAN TRANSPLANTATION, 2015, 6(5): 331-334, 339. doi: 10.3969/j.issn.1674-7445.2015.05.011

活体肾移植供肾肾小球滤过率对术后移植肾功能恢复的影响

doi: 10.3969/j.issn.1674-7445.2015.05.011
基金项目: 

云南省教育厅科学研究基金项目 2014Y150

云南省卫生科技计划项目 2012ws0019

云南省教育厅科学研究基金项目 2013C245

详细信息
    通讯作者:

    李珍, Email:24225695@qq.com

  • 中图分类号: R617

Influence of glomerular filtration rate of living donor on recovery of graft function after transplantation

More Information
  • 摘要:   目的  探讨活体肾移植供肾肾小球滤过率(GFR)对术后移植肾功能恢复的影响。  方法  回顾性分析2009年至2013年在昆明医科大学第一附属医院器官移植中心接受活体供肾移植的108对供受者的临床资料。按供肾GFR数值大小将研究对象分为G1组(GFR < 40 ml/min)、G2组(GFR 40~45 ml/min)、G3组(GFR 46~50 ml/min)及G4组(GFR > 50 ml/min)。比较各组受者术后1周、2周、3周、1个月、3个月、6个月及1年的血清肌酐(Scr)的变化情况, 以及术后1年的人及肾存活情况。  结果  与G1组比较, G2、G3、G4组术后2周、3周、1个月的Scr值较低, 差异有统计学意义(均为P < 0.05), 术后1年内人、肾存活情况, G1组超急性排斥反应致移植肾失功1例、重症肺部感染死亡1例; G2组因急性排斥反应导致移植肾失功1例; G3组死于重症肺部感染者1例; G4组1例死于重症肺部感染; 其余患者在随访期间人、肾均存活。  结论  活体肾移植供肾GFR值低对术后移植肾早期(1个月内)肾功能恢复有一定影响。

     

  • 表  1  4组受者肾移植术后血清肌酐值的比较

    Table  1.   Comparison of serum creatinine values of recipients among 4 groups(μmol/L, x±s)

    组别 n Scr
    术后1周 术后2周 术后3周 术后1个月 术后3个月 术后6个月 术后1年
    G1组 23 105±33 112±47 120±50 127±58 123±56 120±42 116±41
    G2组 28 92±24 91±23a 96±25a 99±28a 111±44 109±31 107±30
    G3组 16 114±49 111±51a 109±48a 105±27a 106±40 99±46 105±39
    G4组 41 106±30 99±34a 106±34a 107±32a 105±25 110±36 105±28
      注:与G1组比较,aP < 0.05
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出版历程
  • 收稿日期:  2015-06-01
  • 网络出版日期:  2021-04-29
  • 刊出日期:  2015-09-01

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