-
摘要: 肾移植供肾短缺日益凸显, 各类非标准供肾的选择对移植肾的保存技术提出了更高要求, 机械灌注保存肾脏相关研究重新兴起。Lifeport作为一款移植肾的机械灌注仪器应用较为广泛, 本文从Lifeport简介、临床研究和基础研究, 不同机械灌注仪器的比较等方面, 对Lifeport在肾移植中的应用研究进展进行综述。
-
[1] Dove A. Nifty transport device doubles durability of donor organs[J]. Nat Med, 2007, 13(4):390. [2] Moers C, Smits JM, Maathuis MH, et al. Machine perfusion or cold storage in deceased-donor kidney transplantation[J]. N Engl J Med, 2009, 360(1):7-19. doi: 10.1056/NEJMoa0802289 [3] Jochmans I, Moers C, Smits JM, et al. Machine perfusion versus cold storage for the preservation of kidneys donated after cardiac death:a multicenter, randomized, controlled trial[J]. Ann Surg, 2010, 252(5):756-764. doi: 10.1097/SLA.0b013e3181ffc256 [4] Treckmann J, Moers C, Smits JM, et al. Machine perfusion versus cold storage for preservation of kidneys from expanded criteria donors after brain death[J]. Transpl Int, 2011, 24(6):548-554. doi: 10.1111/tri.2011.24.issue-6 [5] Forde JC, Shields WP, Azhar M, et al. Single centre experience of hypothermic machine perfusion of kidneys from extended criteria deceased heart-beating donors:a comparative study[J]. Ir J Med Sci, 2014, DOI: 10.1007/s11845-014-1235-8[Epub ahead of print]. [6] Watson CJ, Wells AC, Roberts RJ, et al. Cold machine perfusion versus static cold storage of kidneys donated after cardiac death:a UK multicenter randomized controlled trial[J]. Am J Transplant, 2010, 10(9):1991-1999. doi: 10.1111/j.1600-6143.2010.03165.x [7] Chen G, Ko D, Wang C, et al. Impact of machine perfusion on outcomes of kidney transplantation from donation after cardiac death:a prospective randomized controlled trial[J]. Am J Transplant, 2014, 14(3S):S267. http://www.mendeley.com/research/impact-machine-perfusion-outcomes-kidney-transplantation-donation-after-cardiac-death-prospective-ra/ [8] 潘晓鸣, 薛武军, 刘林娟, 等.西北地区开展公民心脏死亡后捐献肾脏移植的报告[J].南方医科大学学报, 2014, (3):414-418, 433. http://www.cnki.com.cn/Article/CJFDTOTAL-DYJD201403027.htmPan X, Xue W, Liu L, et al. Donations after cardiac death kidney transplantation in northwest China[J]. J South Med Univ, 2014, 34(3):414-418, 433. http://www.cnki.com.cn/Article/CJFDTOTAL-DYJD201403027.htm [9] O'callaghan JM, Morgan RD, Knight SR, et al. Systematic review and meta-analysis of hypothermic machine perfusion versus static cold storage of kidney allografts on transplant outcomes[J]. Br J Surg, 2013, 100(8):991-1001. doi: 10.1002/bjs.9169 [10] Deng R, Gu G, Wang D, et al. Machine perfusion versus cold storage of kidneys derived from donation after cardiac death:a meta-analysis[J]. PLoS One, 2013, 8(3):e56368. doi: 10.1371/journal.pone.0056368 [11] Jiao B, Liu S, Liu H, et al. Hypothermic machine perfusion reduces delayed graft function and improves one-year graft survival of kidneys from expanded criteria donors:a meta-analysis[J]. PLoS One, 2013, 8(12):e81826. doi: 10.1371/journal.pone.0081826 [12] Matas AJ, Smith JM, Skeans MA, et al. OPTN/SRTR 2011 annual data report:kidney[J]. Am J Transplant, 2013, 13(Suppl 1):11-46. https://www.ncbi.nlm.nih.gov/pubmed/23237695 [13] Matas AJ, Smith JM, Skeans MA, et al. OPTN/SRTR 2013 annual data report:kidney[J]. Am J Transplant, 2015, 15(Suppl 2):1-34. https://www.ncbi.nlm.nih.gov/pubmed/25626344 [14] Dare AJ, Pettigrew GJ, Saeb-Parsy K. Preoperative assessment of the deceased-donor kidney:from macroscopic appearance to molecular biomarkers[J]. Transplantation, 2014, 97(8):797-807. doi: 10.1097/01.TP.0000441361.34103.53 [15] Carter JT, Chan S, Roberts JP, et al. Expanded criteria donor kidney allocation:marked decrease in cold ischemia and delayed graft function at a single center[J]. Am J Transplant, 2005, 5(11):2745-2753. doi: 10.1111/ajt.2005.5.issue-11 [16] Yushkov YY, Stern J, Ying A, et al. Identifying risk factors in renal allografts before transplant:machine-measured renal resistance and posttransplant allograft survival[J]. Prog Transplant, 2012, 22(2):175-182. doi: 10.7182/pit2012968 [17] Jochmans I, Moers C, Smits JM, et al. The prognostic value of renal resistance during hypothermic machine perfusion of deceased donor kidneys[J]. Am J Transplant, 2011, 11(10):2214-2220. doi: 10.1111/ajt.2011.11.issue-10 [18] De Vries EE, Hoogland ER, Winkens B, et al. Renovascular resistance of machine-perfused DCD kidneys is associated with primary nonfunction[J]. Am J Transplant, 2011, 11(12):2685-2691. doi: 10.1111/j.1600-6143.2011.03755.x [19] Patel SK, Pankewycz OG, Weber-Shrikant E, et al. Effect of increased pressure during pulsatile pump perfusion of deceased donor kidneys in transplantation[J]. Transplant Proc, 2012, 44(7):2202-2206. doi: 10.1016/j.transproceed.2012.07.109 [20] Patel SK, Pankewycz OG, Nader ND, et al. Prognostic utility of hypothermic machine perfusion in deceased donor renal transplantation[J]. Transplant Proc, 2012, 44(7):2207-2212. doi: 10.1016/j.transproceed.2012.07.129 [21] Moers C, Varnav OC, Van Heurn E, et al. The value of machine perfusion perfusate biomarkers for predicting kidney transplant outcome[J]. Transplantation, 2010, 90(9):966-973. doi: 10.1097/TP.0b013e3181f5c40c [22] Hoogland ER, De Vries EE, Christiaans MH, et al. The value of machine perfusion biomarker concentration in DCD kidney transplantations[J]. Transplantation, 2013, 95(4):603-610. doi: 10.1097/TP.0b013e31827908e6 [23] Bhangoo RS, Hall IE, Reese PP, et al. Deceased-donor kidney perfusate and urine biomarkers for kidney allograft outcomes:a systematic review[J]. Nephrol Dial Transplant, 2012, 27(8):3305-3314. doi: 10.1093/ndt/gfr806 [24] Nagelschmidt M, Minor T, Gallinat A, et al. Lipid peroxidation products in machine perfusion of older donor kidneys[J]. J Surg Res, 2013, 180(2):337-342. doi: 10.1016/j.jss.2012.04.071 [25] Guy AJ, Nath J, Cobbold M, et al. Metabolomic analysis of perfusate during hypothermic machine perfusion of human cadaveric kidneys[J]. Transplantation, 2015, 99(4):754-759. doi: 10.1097/TP.0000000000000398 [26] Nath J, Guy A, Smith TB, et al. Metabolomic perfusate analysis during kidney machine perfusion:the pig provides an appropriate model for human studies[J]. PLoS One, 2014, 9(12):e114818. doi: 10.1371/journal.pone.0114818 [27] Hosgood SA, Yang B, Bagul A, et al. A comparison of hypothermic machine perfusion versus static cold storage in an experimental model of renal ischemia reperfusion injury[J]. Transplantation, 2010, 89(7):830-837. doi: 10.1097/TP.0b013e3181cfa1d2 [28] Chatauret N, Coudroy R, Delpech PO, et al. Mechanistic analysis of nonoxygenated hypothermic machine perfusion's protection on warm ischemic kidney uncovers greater eNOS phosphorylation and vasodilation[J]. Am J Transplant, 2014, 14(11):2500-2514. doi: 10.1111/ajt.12904 [29] Sedigh A, Larsson R, Brannstrom J, et al. Modifying the vessel walls in porcine kidneys during machine perfusion[J]. J Surg Res, 2014, 191(2):455-462. doi: 10.1016/j.jss.2014.04.006 [30] Codas R, Thuillier R, Delpech PO, et al. The final showdown:preclinic comparison between perfusion machines ORS Lifeport and Waters RM3[J]. Transplant Int, 2012, 25:15-16. https://www.researchgate.net/publication/296756151_THE_FINAL_SHOWDOWN_PRECLINICAL_COMPARISON_BETWEEN_PERFUSION_MACHINES_ORS_LIFEPORT_AND_WATERS_RM3 [31] Wszola M, Domagala P, Diuwe P, et al. One-year transplantation results of kidneys preserved by machine perfusion:lifeport kidney transporter versus Waters RM3-prospective study[J]. Am J Transplant, 2012, 12(3S):S221. [32] Lindell SL, Muir H, Brassil J, et al. Hypothermic machine perfusion preservation of the DCD kidney:machine effects[J]. J Transplant, 2013:802618. https://www.ncbi.nlm.nih.gov/pubmed/24222842 [33] Wszola M, Kwiatkowski A, Latek M, et al. Long term medical and economical benefit of machine perfusion (MP) kidney storage in comparison to cold storage (CS)[J]. Ann Transplant, 2009, 14(2):24-29. https://www.ncbi.nlm.nih.gov/pubmed/19487790 [34] Groen H, Moers C, Smits JM, et al. Cost-effectiveness of hypothermic machine preservation versus static cold storage in renal transplantation[J]. Am J Transplant, 2012, 12(7):1824-1830. doi: 10.1111/j.1600-6143.2012.04030.x
点击查看大图
计量
- 文章访问数: 182
- HTML全文浏览量: 44
- PDF下载量: 13
- 被引次数: 0