Rh-positive patients receiving kidney grafts from Rh-negative cadaver donor: a report of two cases and literature review
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摘要:
目的 探讨Rh阳性患者接受Rh阴性尸体供肾肾移植的安全性。 方法 2013年11月29日,第四军医大学西京医院泌尿外科为两例Rh阳性患者实施Rh阴性尸体供肾肾移植术。回顾性分析两例患者的临床资料并复习相关文献。 结果 两例患者手术成功,术后均未出现超急性排斥反应或急性排斥反应。随访12个月,移植肾存活良好,患者无明显不适。 结论 通过术前加强免疫抑制,充分灌注及严密术后监测,Rh阳性患者接受Rh阴性尸体供肾肾移植是安全的。 Abstract:Objective To discuss the safety of Rh-positive patients receiving kidney grafts from Rh-negative cadaver donor. Methods On November 29th 2013, two Rh-positive patients received renal transplantation with kidney grafts from Rh-negative cadaver donor at the Department of Urinary Surgery of Xijing Hospital, the Fourth Military Medical University. The clinical data of the two patients were analyzed retrospectively and the relevant literatures were reviewed. Results The two patients underwent renal transplantation successfully and no hyperacute rejection or acute rejection occured after the surgery. The two patients were followed up for 12 months. The kidney grafts survived well and the patients had no obvious discomfort. Conclusions Through enhanced immunosuppression before operation, sufficient perfusion and close postoperative monitoring, it is safe for Rh-positive patients receiving kidney grafts from Rh-negative cadaver donor. -
表 1 肾移植患者(例2)术后检测指标及其处理措施
Table 1. Indicators and treatments of the renal transplant patient after operation(case 2)
时 间 血红蛋白(g/L) Scr(μmol/L) 总胆红素(μmol/L) 尿胆原 处理措施 手术当日 - 565 - - - 术后第1日 70 463 - - 给予B型Rh阳性少白红细胞悬液2 U静脉输注 术后第2日 66 245 25.4 阳性 患者无明显不适,复查腹部超声见移植肾血流良好,给予B型Rh阳性少白红细胞悬液4 U静脉输注 术后第3日 90 184 22.4 阳性 给予B型Rh阳性少白红细胞悬液3 U静脉输注 术后第4日 115 - - - - 术后第10日 118 122 - - 无明显不适,康复出院 -
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