肾移植术后BK病毒相关性肾病合并环孢素中毒1例报告

解俊杰; 范宇; 柏宏伟; 李钢; 刘路鹏; 钱叶勇

doi:10.3969/j.issn.1674-7445.2014.06.011

肾移植术后BK病毒相关性肾病合并环孢素中毒1例报告

doi: 10.3969/j.issn.1674-7445.2014.06.011

100091 北京, 解放军第309医院器官移植研究所泌尿二科

基金项目:

首都临床特色应用研究 Z131107002213139

详细信息

通讯作者:
钱叶勇, Email:qianyy@medmail.com.cn

中图分类号: R617
计量
- 文章访问数: 93
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- PDF下载量: 13
- 被引次数: 0
出版历程
- 收稿日期: 2014-08-26
- 网络出版日期: 2021-01-19
- 刊出日期: 2014-11-15

摘要

- 肾移植 /
- BK病毒相关性肾病 /
- 环孢素 /
- 药物中毒

HTML全文

图 1 肾移植术后BK病毒相关性肾病合并环孢素中毒患者的移植肾组织病理表现

注：A图为发病时表现(免疫组织化学染色，×400) ，可见肾小球系膜基质节段性轻微增生，细小动脉分支基本正常，肾小管上皮细胞水肿、变性及细胞核消失，极少数肾小管坏死并脱落于管腔；C4d(－)；BKV T抗原染色(+)，即提示BKV(+)。B图为治疗后4个月表现(免疫组织化学染色，×800) ，BKV(－)

Figure 1. Pathological features of renal allograft tissue of patients with BK virus associated nephropathy combined with cyclosporine toxicity after renal transplantation

下载: 全尺寸图片幻灯片

参考文献(12)

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[9]	Geddes CC, Gunson R, Mazonakis E, et al. BK viremia surveillance after kidney transplant: single-center experience during a change from cyclosporine-tolower-dose tacrolimus-based primary immunosuppression regimen[J]. Transpl Infect Dis, 2011, 13(2): 109-116. doi: 10.1111/tid.2011.13.issue-2
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[12]	解俊杰, 钱叶勇, 石炳毅, 等. 抢救性治疗对肾移植后BK病毒感染及其相关性肾病的临床效果[J]. 中华器官移植杂志, 2013, 34(2): 105-109. Xie JJ, Qian YY, Shi BY, et al. Clinical observation of BK viremia and BK virus-associated nephropathy with rescuing therapy in renal transplant recipients[J]. Chin J Organ Transplant, 2013, 34(2): 105-109.