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米克热衣·艾孜买提, 热衣汉·西里甫, 刘健, 等. 活体肾移植供者安全性的随访观察[J]. 器官移植, 2014, 5(6): 364-367. doi: 10.3969/j.issn.1674-7445.2014.06.008
引用本文: 米克热衣·艾孜买提, 热衣汉·西里甫, 刘健, 等. 活体肾移植供者安全性的随访观察[J]. 器官移植, 2014, 5(6): 364-367. doi: 10.3969/j.issn.1674-7445.2014.06.008
, , Liu Jian, et al. Follow-up observation on the safety of donors for living donor renal transplantation[J]. ORGAN TRANSPLANTATION, 2014, 5(6): 364-367. doi: 10.3969/j.issn.1674-7445.2014.06.008
Citation: , , Liu Jian, et al. Follow-up observation on the safety of donors for living donor renal transplantation[J]. ORGAN TRANSPLANTATION, 2014, 5(6): 364-367. doi: 10.3969/j.issn.1674-7445.2014.06.008

活体肾移植供者安全性的随访观察

doi: 10.3969/j.issn.1674-7445.2014.06.008
基金项目: 

国家自然科学基金 811160095

详细信息
    通讯作者:

    桑晓红, Email:1213850212@qq.com

  • 中图分类号: R617

Follow-up observation on the safety of donors for living donor renal transplantation

More Information
  • 摘要:   目的  探讨活体肾移植对供者安全性的影响。  方法   研究对象为2003年4月至2007年4月在新疆医科大学第一附属医院完成活体供肾肾移植的62例供者。记录供者手术时间和住院时间, 观察术后并发症发生情况和预后情况。术后随访, 随访内容包括血清肌酐(Scr)、血尿素氮(BUN)、肾小球滤过率(GFR)、血浆白蛋白、血红蛋白及血压等指标, 同时调查供肾对生活工作的影响。  结果   62例供者供肾手术均获成功。供者中1例开放取肾术中发生气胸, 1例发生切口脂肪液化坏死, 经对症治疗后痊愈。2 例术后并发肺部感染, 选用敏感抗生素及雾化吸入治疗后治愈, 其余术后均恢复顺利。62例供者平均术后住院时间(8.2±2.6)d, 随访时间为(3.2±1.1)年。所有供者均存活, 家庭生活和日常工作也未受到明显影响。62例供者术前及术后7 d、3个月、1年、3年、5年的Scr、BUN、GFR、血浆白蛋白、血红蛋白及血压变化情况比较, 差异无统计学意义(均为P>0.05)。  结论   活体供肾肾切除手术安全可行。严格完善术前检查, 术中仔细操作及术后严密随访对于保障供者的安全有十分重要的意义。

     

  • 表  1  62例活体肾移植供者手术前后各指标变化情况

    Table  1.   Changes of each index of 62 donors with living donor renal transplantation before and after operation(x±s)

    时间nScr(μmol/L)BUN(mmol/L)GFR(ml/min)白蛋白(g/L)血红蛋白(g/L)收缩压(mmHg)舒张压(mmHg)
    术前6278.4±2.25.1±0.1101.8±0.742.7±0.6135.8±2.9114.6±1.173.9±0.9
    术后7 d6294.9±2.45.7±0.6102.0±0.741.5±0.6131.5±2.2120.3±0.680.4±0.6
    术后3个月6284.8±1.65.2±0.1100.8±0.644.0±0.4124.7±2.1119.4±0.779.5±0.5
    术后1年6093.7±1.85.3±0.1100.4±0.744.3±0.8121.5±1.5121.1±0.679.4±0.6
    术后3年5592.2±1.45.2±0.1101.0±0.744.9±0.4108.9±2.0120.6±0.580.1±0.6
    术后5年4689.3±1.55.2±0.1101.2±0.745.2±0.4112.2±1.5120.7±0.579.3±0.6
    注:10 mmHg=1.33 kPa
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出版历程
  • 收稿日期:  2014-07-18
  • 网络出版日期:  2021-01-19
  • 刊出日期:  2014-11-15

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