肝移植术后免疫耐受生物学标志的研究进展

李心鑫; 曾强; 窦剑

doi:10.3969/j.issn.1674-7445.2014.02.015

肝移植术后免疫耐受生物学标志的研究进展

doi: 10.3969/j.issn.1674-7445.2014.02.015

050051 石家庄, 河北医科大学第三医院肝胆外科

详细信息

通讯作者:
窦剑,Email:2423978344@qq.com

中图分类号: R617
计量
- 文章访问数: 89
- HTML全文浏览量: 29
- PDF下载量: 10
- 被引次数: 0
出版历程
- 收稿日期: 2013-12-26
- 网络出版日期: 2021-01-26
- 刊出日期: 2014-03-15

摘要

- 肝移植 /
- 生物学标志 /
- 免疫耐受

HTML全文

参考文献(30)

[1]	Martínez-Llordella M, Puig-Pey I, Orlando G, et al. Multiparameter immune profiling of operational tolerance in liver transplantation[J]. Am J Transplant,2007,7(2):309-319. doi: 10.1111/ajt.2007.7.issue-2
[2]	Benseler V, McCaughan GW, Schlitt HJ, et al. The liver: a special case in transplantation tolerance[J]. Semin Liver Dis,2007,27(2):194-213. doi: 10.1055/s-2007-979471
[3]	Starzl TE, Murase N, Abu-Elmagd K, et al. Tolerogenic immunosuppression for organ transplantation[J]. Lancet,2003,361(9368):1502-1510. doi: 10.1016/S0140-6736(03)13175-3
[4]	Musat AI, Agni RM, Wai PY, et al. The significance of donor-specific HLA antibodies in rejection and ductopenia development in ABO compatible liver transplantation[J]. Am J Transplant,2011,11(3):500-510. doi: 10.1111/j.1600-6143.2010.03414.x
[5]	Demetris AJ, Lunz JG 3rd, Randhawa P, et al. Monitoring of human liver and kidney allograft tolerance: a tissue/histopathology perspective[J]. Transpl Int,2009,22(1):120-141. doi: 10.1111/tri.2008.22.issue-1
[6]	黎介寿,郑树森. 肝移植[M]. 2版. 北京:人民卫生出版社,2012. Li JS, Zheng SS. Liver Transplantation[M]. 2ed. Beijing: People's Medical Publishing House, 2012.
[7]	罗柳平,郑琳,陈丽红,等.联合输注受者Treg细胞和供者未成熟DC延长肝移植大鼠的存活时间[J].中华器官移植杂志,2012,33(10):619-623. Luo LP, Zheng L, Chen LH, et al. Inducement of rat liver transplantation tolerance by Treg cells and imDCs[J]. Chin J Organ Transplant,2012,33(10):619-623.
[8]	刘宝阳,张磊,戈海泽,等.大鼠肝移植术后肝脏T淋巴细胞凋亡与免疫耐受的关系[J].器官移植,2012,3(4):213-218. http://www.organtranspl.com/browse/detail/qkid/59/id/611.html Liu BY, Zhang L, Ge HZ, et al. Relationship between immune tolerance and hepatic T lymphocytes apoptosis after liver transplantation in rats[J].Organ Transplant, 2012,3(4):213-218. http://www.organtranspl.com/browse/detail/qkid/59/id/611.html
[9]	Feng S, Ekong UD, Lobritto SJ, et al. Complete immunosuppression withdrawal and subsequent allograft function among pediatric recipients of parental living donor liver transplants[J]. JAMA,2012,307(3):283-293. http://cn.bing.com/academic/profile?id=2117600377&encoded=0&v=paper_preview&mkt=zh-cn
[10]	Tisone G, Orlando G, Cardillo A, et al. Complete weaning off immunosuppression in HCV liver transplant recipients is feasible and favourably impacts on the progression of disease recurrence[J]. J Hepatol,2006,44(4):702-709. doi: 10.1016/j.jhep.2005.11.047
[11]	Donckier V, Craciun L, Miqueu P, et al. Expansion of memory-type CD8⁺ T cells correlates with the failure of early immunosuppression withdrawal after cadaver liver transplantation using high-dose ATG induction and rapamycin[J]. Transplantation,2013,96(3):306-315. doi: 10.1097/TP.0b013e3182985414
[12]	Golshayan D, Wyss JC, Abulker CW, et al. Transplantation tolerance induced by regulatory T cells: in vivo mechanisms and sites of action[J]. Int Immunopharmacol,2009,9(6):683-688. doi: 10.1016/j.intimp.2008.12.006
[13]	Xufré C, Costa M, Roura-Mir C, et al. Low frequency of GITR⁺ T cells in ex vivo and in vitro expanded Treg cells from type 1 diabetic patients[J]. Int Immunol,2013,25(10):563-574. doi: 10.1093/intimm/dxt020
[14]	Gill RG. An orchestrated dance between differing regulatory T cell phenotypes in allograft tolerance[J]. Am J Transplant,2013,13(8):1945-1946. doi: 10.1111/ajt.12336
[15]	Golshayan D, Jiang S, Tsang J, et al. In vitro-expanded donor alloantigen-specific CD4⁺ CD25⁺ regulatory T cells promote experimental transplantation tolerance[J]. Blood,2007,109(2):827-835. doi: 10.1182/blood-2006-05-025460
[16]	Sagoo P, Lombardi G, Lechler RI. Relevance of regulatory T cell promotion of donor-specific tolerance in solid organ transplantation[J]. Front Immunol,2012,3:184. http://cn.bing.com/academic/profile?id=2118836795&encoded=0&v=paper_preview&mkt=zh-cn
[17]	Mazariegos GV, Zahorchak AF, Reyes J, et al. Dendritic cell subset ratio in tolerant, weaning and non-tolerant liver recipients is not affected by extent of immunosuppression[J]. Am J Transplant,2005,5(2):314-322. doi: 10.1111/ajt.2005.5.issue-2
[18]	Tokita D, Mazariegos GV, Zahorchak AF, et al. High PD-L1/CD86 ratio on plasmacytoid dendritic cells correlates with elevated T-regulatory cells in liver transplant tolerance[J]. Transplantation,2008,85(3):369-377. doi: 10.1097/TP.0b013e3181612ded
[19]	Li Y, Koshiba T, Yoshizawa A, et al. Analyses of peripheral blood mononuclear cells in operational tolerance after pediatric living donor liver transplantation[J]. Am J Transplant,2004,4(12):2118-2125. doi: 10.1111/ajt.2004.4.issue-12
[20]	Pham B, Piard-Ruster K, Silva R, et al. Changes in natural killer cell subsets in pediatric liver transplant recipients[J]. Pediatr Transplant,2012,16(2):176-182. doi: 10.1111/petr.2012.16.issue-2
[21]	Martínez-Llordella M, Lozano JJ, Puig-Pey I, et al. Using transcriptional profiling to develop a diagnostic test of operational tolerance in liver transplant recipients[J]. J Clin Invest,2008,118(8):2845-2857. http://cn.bing.com/academic/profile?id=2108024885&encoded=0&v=paper_preview&mkt=zh-cn
[22]	Chen Y, Liu Z, Liang S, et al. Role of Kupffer cells in the induction of tolerance of orthotopic liver transplantation in rats[J]. Liver Transpl,2008,14(6):823-836. doi: 10.1002/(ISSN)1527-6473
[23]	Castellaneta A, Mazariegos GV, Nayyar N, et al. HLA-G level on monocytoid dendritic cells correlates with regulatory T-cell Foxp3 expression in liver transplant tolerance[J]. Transplantation,2011,91(10):1132-1140. doi: 10.1097/TP.0b013e31821414c9
[24]	Deschaseaux F, Delgado D, Pistoia V, et al. HLA-G in organ transplantation: towards clinical applications[J]. Cell Mol Life Sci,2011,68(3):397-404. doi: 10.1007/s00018-010-0581-6
[25]	杨扬,张英才. 肝移植术后免疫抑制剂撤退的研究进展[J]. 器官移植,2013,4(6):320-324. http://www.organtranspl.com/browse/detail/qkid/67/id/251.html Yang Y, Zhang YC. Research progress of immunosuppressant withdrawing after liver transplantation[J]. Organ Transplant,2013,4(6):320-324. http://www.organtranspl.com/browse/detail/qkid/67/id/251.html
[26]	Charles R, Chou HS, Wang L, et al. Human hepatic stellate cells inhibit T-cell response through B7-H1 pathway[J]. Transplantation,2013,96(1):17-24. doi: 10.1097/TP.0b013e318294caae
[27]	Wood KJ, Goto R. Mechanisms of rejection: current perspectives[J]. Transplantation,2012,93(1):1-10. doi: 10.1097/TP.0b013e31823cab44
[28]	Bohne F, Martínez-Llordella M, Lozano JJ, et al. Intra-graft expression of genes involved in iron homeostasis predicts the development of operational tolerance in human liver transplantation[J]. J Clin Invest,2012,122(1):368-382. doi: 10.1172/JCI59411
[29]	Feng S, Ekong UD, Lobritto SJ, et al. Complete immunosuppression withdrawal and subsequent allograft function among pediatric recipients of parental living donor liver transplants[J]. JAMA,2012,307(3):283-293. http://cn.bing.com/academic/profile?id=2117600377&encoded=0&v=paper_preview&mkt=zh-cn
[30]	Heidt S, San Segundo D, Shankar S, et al. Peripheral blood sampling for the detection of allograft rejection: biomarker identification and validation[J]. Transplantation,2011,92(1):1-9. doi: 10.1097/TP.0b013e318218e978