留言板

尊敬的读者、作者、审稿人, 关于本刊的投稿、审稿、编辑和出版的任何问题, 您可以本页添加留言。我们将尽快给您答复。谢谢您的支持!

姓名
邮箱
手机号码
标题
留言内容
验证码

调节性T细胞在器官移植免疫耐受中的研究进展

唐韵成 曾强 窦剑

唐韵成, 曾强, 窦剑. 调节性T细胞在器官移植免疫耐受中的研究进展[J]. 器官移植, 2014, 5(1): 54-56. doi: 10.3969/j.issn.1674-7445.2014.01.014
引用本文: 唐韵成, 曾强, 窦剑. 调节性T细胞在器官移植免疫耐受中的研究进展[J]. 器官移植, 2014, 5(1): 54-56. doi: 10.3969/j.issn.1674-7445.2014.01.014

调节性T细胞在器官移植免疫耐受中的研究进展

doi: 10.3969/j.issn.1674-7445.2014.01.014
基金项目: 

河北省医学科学重点课题计划项目 20130220

详细信息
    通讯作者:

    窦剑,Email:j-douchina1114@yahoo.com

  • 中图分类号: R617

  • [1] Lamb KE, Lodhi S, Meier-Kriesche HU. Long-term renal allograft survival in the United States: a critical reappraisal[J]. Am J Transplant,2011,11(3):450-462. doi: 10.1111/j.1600-6143.2010.03283.x
    [2] Sakaguchi S, Sakaguchi N, Asano M, et al. Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25): breakdown of a single mechanism of self-tolerance causes various autoimmune diseases[J]. J Immunol,1995,155(3):1151-1164. http://cn.bing.com/academic/profile?id=1567420244&encoded=0&v=paper_preview&mkt=zh-cn
    [3] Baecher-Allan C, Brown JA, Freeman GJ, et al. CD4+ CD25high regulatory cells in human peripheral blood[J]. J Immunol,2001,167(3):1245-1253. doi: 10.4049/jimmunol.167.3.1245
    [4] Khan MA, Moeez S, Akhtar S. T-regulatory cell-mediated immune tolerance as a potential immunotherapeutic strategy to facilitate graft survival[J]. Blood Transfus,2013,11(3):357-363. http://cn.bing.com/academic/profile?id=2201462157&encoded=0&v=paper_preview&mkt=zh-cn
    [5] Lehtimäki S, Lahesmaa R. Regulatory T cells control immune responses through their non-redundant tissue specific features[J]. Front Immunol,2013,4:294. http://cn.bing.com/academic/profile?id=2074088449&encoded=0&v=paper_preview&mkt=zh-cn
    [6] Roncador G, Brown PJ, Maestre L, et al. Analysis of FOXP3 protein expression in human CD4+ CD25+ regulatory T cells at the single-cell level[J]. Eur J Immunol,2005,35(6):1681-1691. doi: 10.1002/(ISSN)1521-4141
    [7] Fontenot JD, Gavin MA, Rudensky AY. Foxp3 programs the development and function of CD4+ CD25+ regulatory T cells[J]. Nat Immunol,2003,4(4):330-336. doi: 10.1038/ni904
    [8] Ohkura N, Kitagawa Y, Sakaguchi S. Development and maintenance of regulatory T cells[J]. Immunity,2013,38(3):414-423. doi: 10.1016/j.immuni.2013.03.002
    [9] Liu W, Putnam AL, Xu-Yu Z, et al. CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells[J]. J Exp Med,2006,203(7):1701-1711. doi: 10.1084/jem.20060772
    [10] Seddiki N, Santner-Nanan B, Martinson J, et al. Expression of interleukin (IL)-2 and IL-7 receptors discriminates between human regulatory and activated T cells[J]. J Exp Med,2006,203(7):1693-1700. doi: 10.1084/jem.20060468
    [11] Kleinewietfeld M, Starke M, Di Mitri D, et al. CD49d provides access to "untouched" human Foxp3+ Treg free of contaminating effector cells[J]. Blood,2009,113(4):827-836. doi: 10.1182/blood-2008-04-150524
    [12] Kachapati K, Adams DE, Wu Y, et al. The B10 Idd9.3 locus mediates accumulation of functionally superior CD137(+) regulatory T cells in the nonobese diabetic type 1 diabetes model[J]. J Immunol,2012,189(10):5001-5015. doi: 10.4049/jimmunol.1101013
    [13] Kataoka H, Takahashi S, Takase K, et al. CD25(+)CD4(+) regulatory T cells exert in vitro suppressive activity independent of CTLA-4[J]. Int Immunol,2005,17(4):421-427. doi: 10.1093/intimm/dxh221
    [14] Miyara M, Yoshioka Y, Kitoh A, et al. Functional delineation and differentiation dynamics of human CD4+ T cells expressing the FoxP3 transcription factor[J]. Immunity,2009,30(6):899-911. doi: 10.1016/j.immuni.2009.03.019
    [15] Bluestone JA, Abbas AK. Natural versus adaptive regulatory T cells[J]. Nat Rev Immunol,2003,3(3):253-257. doi: 10.1038/nri1032
    [16] Steger U, Kingsley CI, Karim M, et al. CD25+CD4+ regulatory T cells develop in mice not only during spontaneous acceptance of liver allografts but also after acute allograft rejection[J]. Transplantation,2006,82(9):1202-1209. doi: 10.1097/01.tp.0000235913.58337.b4
    [17] Veronese F, Rotman S, Smith RN, et al. Pathological and clinical correlates of FOXP3+ cells in renal allografts during acute rejection[J]. Am J Transplant,2007,7(4):914-922. doi: 10.1111/ajt.2007.7.issue-4
    [18] Dijke IE, Velthuis JH, Caliskan K, et al. Intragraft FOXP3 mRNA expression reflects antidonor immune reactivity in cardiac allograft patients[J]. Transplantation,2007,83(11):1477-1484. doi: 10.1097/01.tp.0000264997.53153.8b
    [19] Aquino-Dias EC, Joelsons G, da Silva DM, et al. Non-invasive diagnosis of acute rejection in kidney transplants with delayed graft function[J]. Kidney Int,2008,73(7):877-884. doi: 10.1038/sj.ki.5002795
    [20] Pesenacker AM, Bending D, Ursu S, et al. CD161 defines the subset of FoxP3+ T cells capable of producing proinflammatory cytokines[J]. Blood,2013,121(14):2647-2658. doi: 10.1182/blood-2012-08-443473
    [21] Demirkiran A, Kok A, Kwekkeboom J, et al. Low circulating regulatory T-cell levels after acute rejection in liver transplantation[J]. Liver Transpl,2006,12(2):277-284. doi: 10.1002/(ISSN)1527-6473
    [22] Segundo DS, Ruiz JC, Izquierdo M, et al. Calcineurin inhibitors, but not rapamycin, reduce percentages of CD4+ CD25+FOXP3+ regulatory T cells in renal transplant recipients[J]. Transplantation,2006,82(4):550-557. doi: 10.1097/01.tp.0000229473.95202.50
    [23] Akimova T, Kamath BM, Goebel JW, et al. Differing effects of rapamycin or calcineurin inhibitor on T-regulatory cells in pediatric liver and kidney transplant recipients[J]. Am J Transplant,2012,12(12):3449-3461. doi: 10.1111/ajt.2012.12.issue-12
    [24] Hall BM, Jelbart ME, Gurley KE, et al. Specific unresponsiveness in rats with prolonged cardiac allograft survival after treatment with cyclosporine. Mediation of specific suppression by T helper/inducer cells[J]. J Exp Med,1985,162(5):1683-1694. doi: 10.1084/jem.162.5.1683
    [25] Joffre O, Santolaria T, Calise D, et al. Prevention of acute and chronic allograft rejection with CD4+ CD25+Foxp3+ regulatory T lymphocytes[J]. Nat Med,2008,14(1):88-92. doi: 10.1038/nm1688
    [26] Trzonkowski P, Bieniaszewska M, Juścińska J, et al. First-in-man clinical results of the treatment of patients with graft versus host disease with human ex vivo expanded CD4+ CD25+ CD127- T regulatory cells[J]. Clin Immunol,2009,133(1):22-26. doi: 10.1016/j.clim.2009.06.001
    [27] Brunstein CG, Miller JS, Cao Q, et al. Infusion of ex vivo expanded T regulatory cells in adults transplanted with umbilical cord blood: safety profile and detection kinetics[J]. Blood,2011,117(3):1061-1070. doi: 10.1182/blood-2010-07-293795
    [28] Di Ianni M, Falzetti F, Carotti A, et al. Tregs prevent GVHD and promote immune reconstitution in HLA-haploidentical transplantation[J]. Blood,2011,117(14):3921-3928. doi: 10.1182/blood-2010-10-311894
  • 加载中
计量
  • 文章访问数:  89
  • HTML全文浏览量:  45
  • PDF下载量:  12
  • 被引次数: 0
出版历程
  • 收稿日期:  2013-11-09
  • 网络出版日期:  2021-01-19
  • 刊出日期:  2014-01-15

目录

    /

    返回文章
    返回