肺移植全球发展概况与展望

焦国慧; 王梓涛; 陈静瑜

doi:10.3969/j.issn.1674-7445.2022.04.002

肺移植全球发展概况与展望

doi: 10.3969/j.issn.1674-7445.2022.04.002

214000 江苏无锡，南京医科大学附属无锡人民医院江苏省肺移植中心无锡市器官移植研究院

基金项目:

国家自然科学基金面上项目 82070059

详细信息

作者简介:

通讯作者:
陈静瑜，Email：chenjy@wuxiph.com

中图分类号: R617, R563
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出版历程
- 收稿日期: 2022-04-14
- 网络出版日期: 2022-07-14
- 刊出日期: 2022-07-15

Current status and prospect of global development of lung transplantation

The Affiliated Wuxi People's Hospital of Nanjing Medical University, Jiangsu Lung Transplant Center, Wuxi Lung Transplant Center, Wuxi 214000, China

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Corresponding author: Chen Jingyu, Email: chenjy@wuxiph.com

摘要

摘要: 在2020年至2021年新型冠状病毒肺炎（新冠肺炎）疫情流行期间，全球肺移植进入新发展阶段。全球范围内，上报国际心肺移植学会（ISHLT）的肺移植数据已经超过70 000例。肺移植供者和受者特征、儿童肺移植受者的适应证随着时间和医疗技术的发展，发生了巨大的变化。肺移植在新冠肺炎相关急性呼吸窘迫综合征（ARDS）患者中的治疗也受到全球瞩目。肺移植外科技术不断发展，也将与更多的新技术融合，在人工肺脏和异种移植领域获得新的突破。本文总结了全球肺移植供、受者特征研究的最新进展，并进一步展望未来发展的趋势，以期终末期肺病患者能够从肺移植技术发展中得到更多获益。
- 肺移植 /
- 新型冠状病毒肺炎 /
- 急性呼吸窘迫综合征(ARDS) /
- 心脏死亡器官捐献(DCD) /
- 离体肺灌注(EVLP) /
- 肺源分配评分(LAS) /
- 体外膜肺氧合(ECMO) /
- 异种器官移植
Abstract: During the novel coronavirus pneumonia (COVID-19) pandemic from 2020 to 2021, lung transplantation entered a new stage of development worldwide. Globally, more than 70 000 cases of lung transplantation have been reported to the International Society for Heart and Lung Transplantation (ISHLT). With the development of medical techniques over time, the characteristics of lung transplant donors and recipients and the indications of pediatric lung transplantation recipients have undergone significant changes. Application of lung transplantation in the treatment of COVID-19-related acute respiratory distress syndrome (ARDS) has also captivated worldwide attention. Along with persistent development of lung transplantation, it will be integrated with more novel techniques to make breakthroughs in the fields of artificial lung and xenotransplantation. In this article, research progresses on the characteristics of lung transplant donors and recipients around the world were reviewed and the development trend was predicted, enabling patients with end-stage lung disease to obtain more benefits from the development of lung transplantation technique.
- Lung transplantation /
- Novel coronavirus pneumonia /
- Acute respiratory distress syndrome (ARDS) /
- Donation after cardiac death (DCD) /
- Ex vivo lung perfusion (EVLP) /
- Lung allocation score (LAS) /
- Extracorporeal membrane oxygenation (ECMO) /
- Xenotransplantation

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