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炎症生物标志物对肝癌肝移植预后的预测作用

牛义善 曾强

牛义善, 曾强. 炎症生物标志物对肝癌肝移植预后的预测作用[J]. 器官移植, 2022, 13(1): 49-54. doi: 10.3969/j.issn.1674-7445.2022.01.008
引用本文: 牛义善, 曾强. 炎症生物标志物对肝癌肝移植预后的预测作用[J]. 器官移植, 2022, 13(1): 49-54. doi: 10.3969/j.issn.1674-7445.2022.01.008
Niu Yishan, Zeng Qiang. Predictive effect of inflammatory biomarkers on prognosis of liver transplantation for hepatocellular carcinoma[J]. ORGAN TRANSPLANTATION, 2022, 13(1): 49-54. doi: 10.3969/j.issn.1674-7445.2022.01.008
Citation: Niu Yishan, Zeng Qiang. Predictive effect of inflammatory biomarkers on prognosis of liver transplantation for hepatocellular carcinoma[J]. ORGAN TRANSPLANTATION, 2022, 13(1): 49-54. doi: 10.3969/j.issn.1674-7445.2022.01.008

炎症生物标志物对肝癌肝移植预后的预测作用

doi: 10.3969/j.issn.1674-7445.2022.01.008
基金项目: 

河北省2020年度引进留学人员资助项目 C20200346

详细信息
    作者简介:

    牛义善,男,1997年生,硕士研究生,研究方向为肝移植,Email:1749193537@qq.com

    曾强,博士研究生导师。河北医科大学第三医院肝胆外科副主任医师、副教授。美国MD Anderson Cancer Center访问学者。长期从事肝胆外科及肝移植工作,并开展了肝移植术后管理及免疫耐受方面的科学研究。兼任中华医学会器官移植学分会青年委员、中国医疗保健交流促进会肝脏移植分会代谢管理学组委员、中国抗癌学会腔镜与机器人外科学分会委员、中国微循环学会肝脏微循环专业委员会委员、《器官移植》杂志通讯编委。主持参与多项肝移植方面的研究课题,并荣获河北省卫生厅科技进步一等奖,发表中华系列论文及SCI论文十余篇

    通讯作者:

    曾强,Email:zengqiang457@qq.com

  • 中图分类号: R617, R364.5

Predictive effect of inflammatory biomarkers on prognosis of liver transplantation for hepatocellular carcinoma

More Information
  • 摘要: 肝细胞癌(肝癌)肝移植术后肿瘤复发是影响受者远期生存的主要问题。术前精确评估和合理选择移植受者是影响肝癌移植受者远期预后的关键因素。中性粒细胞、淋巴细胞、C-反应蛋白、血小板、纤维蛋白原(FIB)等是提示机体炎症反应的生物学指标,多项研究发现此类生物学指标不仅可以代表炎症反应,也可将其整合以用于预测肝癌肝移植术后肿瘤复发和受者长期生存率,这其中主要包括中性粒细胞/淋巴细胞比值(NLR)、格拉斯哥预后评分(GPS)、FIB、血小板/淋巴细胞比值(PLR)、预后营养指数(PNI)等。本文就炎症生物标志物对肝癌肝移植预后的预测作用的研究进展做一综述。

     

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出版历程
  • 收稿日期:  2021-08-24
  • 网络出版日期:  2022-01-12
  • 刊出日期:  2022-01-15

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